Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Molecular and fossil evidence place the origin of cichlid fishes long after Gondwanan rifting. [PDF]
Cichlid fishes are a key model system in the study of adaptive radiation, speciation and evolutionary developmental biology. More than 1600 cichlid species inhabit freshwater and marginal marine environments across several southern landmasses.
Alex Dornburg +9 more
core +1 more source
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Background Plastid genomes (plastomes) present great potential in resolving multiscale phylogenetic relationship but few studies have focused on the influence of genetic characteristics of plastid genes, such as genetic variation and phylogenetic ...
Jian Liu, Anders J. Lindstrom, Xun Gong
doaj +1 more source
Exploring deep phylogenies using protein structure : a dissertation submitted in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Biochemistry, Institute of Natural and Mathematical Sciences, Massey University, Auckland, New Zealand [PDF]
Recent times have seen an exponential growth in protein sequence and structure data. The most popular way of characterising newly determined protein sequences is to compare them to well characterised sequences and predict the function of novel sequences ...
Malik, Ashar J
core
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
A molecular phylogenetic study of Deschampsia (Poaceae: Aveneae) inferred from nuclear ITS and plastid trnL sequence data: support for the recognition of Avenella and Vahlodea [PDF]
The circumscription and phylogeny of Deschampsia were studied for the first time by parsimony analysis of nuclear ribosomal internal transcribed spacer (ITS) and plastid trnL intron sequences.
Chiapella, Jorge Oscar
core
Testing use of mitochondrial COI sequences for the identification and phylogenetic analysis of New Zealand caddisflies (Trichoptera) [PDF]
We tested the hypothesis that cytochrome c oxidase subunit 1 (COI) sequences would successfully discriminate recognised species of New Zealand caddisflies. We further examined whether phylogenetic analyses, based on the COI locus, could recover currently
Banks, Jonathan C. +4 more
core +2 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Molecular Genetic Phylogeny of Gossypium L Specimens [PDF]
In the article, the phylogenetic tree of kinship of unique samples created at the Scientific Research Institute of Cotton Selection, Seeding and Cultivation Agrotechnologies and stored in the collection was compiled using molecular markers.
Kurbonov Abrorjon +2 more
doaj +1 more source

