Results 91 to 100 of about 642,316 (296)
Sequential Wnt Agonist Then Antagonist Treatment Accelerates Tissue Repair and Minimizes Fibrosis
iScience, 2020 Summary: Tissue fibrosis compromises organ function and occurs as a potential long-term outcome in response to acute tissue injuries. Currently, lack of mechanistic understanding prevents effective prevention and treatment of the progression from acute ...
Xiao-Jun Tian +7 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
The role of trehalose metabolism in plant growth and stress responses
, 2012 This thesis started with defining plant stress resilience and its societal significance in Chapter 1. We realized that not just the absolute yield matters to farmers but rather the predictability of the yield given the agricultural practices in the socio-
Sedijani, P. +2 more
core
Allicin Regulates Energy Homeostasis through Brown Adipose Tissue
iScience, 2020 Summary: Brown adipose tissue (BAT) is a promising potential therapeutic target for the treatment of obesity and related metabolic diseases. Allicin, a natural product in garlic, has multiple biological and pharmacological functions. However, the role of
Chuanhai Zhang +13 more
doaj +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Gene regulation in seeds: insights into translational dynamics
, 2016 Seeds are unique structures in the plant life cycle. The variation in the timing of seed maturation, dispersion, and the establishment of seed dormancy and longevity, increases the chances of plant survival and enlarge the distance that plants could ...
Bai, B. +2 more
core
Seed dormancy and seed longevity: from genetic variation to gene identification
, 2014 Seed dormancy and seed longevity are the most important survival traits in the soil seed bank. Both traits are induced during seed maturation and evolved to assure seed survival during environmental conditions that cannot support the regular course of ...
Nguyen, T.P. +2 more
core
L-Arabinose induces D-galactose catabolism via the Leloir pathway in Aspergillus nidulans [PDF]
, 2018 L
Németh, Zoltán +10 more
core +1 more source
Control of plant architecture by distinctive TALE homeobox gene interactions
, 2009 In eukaryotes, transcription factor (TF)-based network is a widely used mechanism to regulate fundamental developmental processes. Both animals and plants utilize three-amino-acid-loop-extension (TALE) homeodomain (HD) transcription factors to subdivide ...
Molecular Plant Physiology +2 more
core