Results 131 to 140 of about 642,316 (296)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Relative roles of the hypothalamus, pituitary and photoperiod on fetal sheep prolactin [PDF]

, 2004
Thesis (Ph.D.)--University of Adelaide, School of Molecular and Biomedical Science, Discipline of Physiology ...
Houghton, Daniel Charles
core  

Myceliophthora thermophila Xyr1 is predominantly involved in xylan degradation and xylose catabolism

, 2019
Background Myceliophthora thermophila is a thermophilic ascomycete fungus that is used as a producer of enzyme cocktails used in plant biomass saccharification.
De Vries, Ronald P., Coconi Linares, Nancy, Visser, Jaap, Nicolau De Almeida, Maira, Meijnen, Jean-paul, Dos Santos Gomes, Ana Carolina, Battaglia, Evy, Molecular Plant Physiology, Peng, Mao, Sub Molecular Plant Physiology, de Vries, Ronald P, Falkoski, Daniel   +11 more
core   +1 more source

Molecular physiology of Arc/Arg3.1: The oligomeric state hypothesis of synaptic plasticity. [PDF]

Acta Physiol (Oxf), 2022
Eriksen MS, Bramham CR.
europepmc   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

The Arabidopsis bZIP11 transcription factor links low-energy signalling to auxin-mediated control of primary root growth

, 2017
Plants have to tightly control their energy homeostasis to ensure survival and fitness under constantly changing environmental conditions. Thus, it is stringently required that energy-consuming stress-adaptation and growth-related processes are ...
Lorenzo Pedrotti, Karin Ljung, Hanson, Johannes, Ondřej Novák (132054), Jebasingh Selvanayagam, Prathibha Muralidhara, Molecular Plant Physiology, Lorenzo Pedrotti (438471), Christoph Weiste (685748), Fröschel, Christian, Christian Fröschel (3716953), Johannes Hanson, Wolfgang Dröge-Laser, Ondřej Novák, Hanson, Johannes,, Ljung, Karin, Novák, Ondřej, Dröge-Laser, Wolfgang, Prathibha Muralidhara (3716950), Karin Ljung (259492), Sub Molecular Plant Physiology, Selvanayagam, Jebasingh, Pedrotti, Lorenzo, Christian Fröschel, Weiste, Christoph, Johannes Hanson (3716947), Wolfgang Dröge-Laser (685749), Muralidhara, Prathibha, Christoph Weiste, Jebasingh Selvanayagam (3716956)   +29 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Turning the aquatic weed Azolla into a sustainable crop

, 2017
Growing worldwide demands for food, energy and chemicals threatens natural ecosystems and global climate. Plants are crucial for food production, but may also be used to produce sustainable energy and materials.
Brouwer, P., Sub Molecular Plant Physiology   +1 more
core  

Molecular physiology regulating cold tolerance and acclimation of Caenorhabditis elegans. [PDF]

Proc Jpn Acad Ser B Phys Biol Sci, 2022
Okahata M, Motomura H, Ohta A, Kuhara A.
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source