Results 41 to 50 of about 6,842,401 (297)

TRPC1 Regulates the Activity of a Voltage-Dependent Nonselective Cation Current in Hippocampal CA1 Neurons

Cells, 2020
The cation channel subunit TRPC1 is strongly expressed in central neurons including neurons in the CA1 region of the hippocampus where it forms complexes with TRPC4 and TRPC5.
Frauke Kepura, Eva Braun, Alexander Dietrich, Tim D. Plant   +3 more
doaj   +1 more source

Effect of diet and genotype on the miRNome of mice with altered lipoprotein metabolism

iScience, 2023
Summary: The molecular mechanism by which lipid/lipoprotein biosynthesis is regulated in mammals involves a very large number of genes that are subject to multiple levels of regulation.
Marco Busnelli, Stefano Manzini, Alice Colombo, Elsa Franchi, Matteo Chiara, Gaia Zaffaroni, David Horner, Giulia Chiesa   +7 more
doaj   +1 more source

Trace Element Management in Rice

Agronomy, 2015
Trace elements (TEs) are vital for the operation of metabolic pathways that promote growth and structural integrity. Paddy soils are often prone to TE limitation due to intensive cultivation and irrigation practices.
Abin Sebastian, Majeti Narasimha Vara Prasad   +1 more
doaj   +1 more source

Ovarian tumorB1-mediated heat shock transcription factor 1 deubiquitination is critical for glycolysis and development of endometriosis

iScience, 2022
Summary: Endometriosis is a common chronic condition characterized by abnormal growth of the endometrium outside the uterus. Heat shock transcription factor 1 (HSF1) is a significant regulator of the proteotoxic stress response and plays an essential ...
Xi Ling, Jiayi Lu, Xiaoyun Wang, Lan Liu, Lu Liu, Yadi Wang, Yujun Sun, Chune Ren, Chao Lu, Zhenhai Yu   +9 more
doaj   +1 more source

NETosis: Molecular Mechanisms, Role in Physiology and Pathology

Biochemistry (Moscow), 2020
NETosis is a program for formation of neutrophil extracellular traps (NETs), which consist of modified chromatin decorated with bactericidal proteins from granules and cytoplasm.
N. Vorobjeva, B. Chernyak
semanticscholar   +1 more source

MYCT1 alters the glycogen shunt by regulating selective translation of RACK1-mediated enzymes

iScience, 2022
Summary: MYCT1 has been shown to function as a tumor suppressor in various tumors, but its role in metabolism has never been reported. Here, we showed that global inactivation of Myct1 in mice led to progressive accumulation of glycogen in the liver ...
Dong-Xue Ding, Yue Wang, Wei Yan, Wei-Neng Fu   +3 more
doaj   +1 more source

The sinusoidal hematopoietic niche is formed by Jam1a via Notch signaling in the zebrafish kidney

iScience, 2023
Summary: The zebrafish is a unique model to understand hematopoietic niches as hematopoietic stem/progenitor cells are maintained in the kidney. However, little is known about which cell types in the kidney play a role in hematopoietic niches.
Mao Kondo, Koki Kimura, Jingjing Kobayashi-Sun, Shiori Yamamori, Makoto Taniguchi, David Traver, Isao Kobayashi   +6 more
doaj   +1 more source

Gene expression plasticity in Pocillopora corals from 2 locations on the Carrizales Reef, Pacific coast of Mexico

Ciencias Marinas, 2020
The greatest threat scleractinian corals face today is accelerated climate change. Assuming that most scleractinians are incapable of genetic adaptation to rapid global changes, the alternative response would be phenotypic plasticity, which is ...
M Alejandro Delgadillo-Nuño, Marco A Liñán-Cabello, Erick Delgadillo-Nuño, Clara E Galindo-Sánchez, Eugenio de Jesús Carpizo-Ituarte   +4 more
doaj   +1 more source

Global-run on sequencing identifies Gm11967 as an Akt-dependent long noncoding RNA involved in insulin sensitivity

iScience, 2022
Summary: The insulin responsive Akt and FoxO1 signaling axis is a key regulator of the hepatic transcriptional response to nutrient intake. Here, we used global run-on sequencing (GRO-seq) to measure the nascent transcriptional response to fasting and ...
Dominic Santoleri, Hee-Woong Lim, Matthew J. Emmett, Julian Stoute, Matthew J. Gavin, Jaimarie Sostre-Colón, Kahealani Uehara, Jaclyn E. Welles, Kathy Fange Liu, Mitchell A. Lazar, Paul M. Titchenell   +10 more
doaj   +1 more source

Exploring the role of grafting in abiotic stress management: Contemporary insights and automation trends

Plant Direct
Grafting is a technique that involves attaching a rootstock to the aerial part of another genotype or species (scion), leading to improved crop performance and sustainable growth.
Kaukab Razi, Preethika Suresh, Pritam Paramguru Mahapatra, Musa Al Murad, Ajila Venkat, Michitaka Notaguchi, Dong Won Bae, Muthu Arjuna Samy Prakash, Sowbiya Muneer   +8 more
doaj   +1 more source