Results 61 to 70 of about 4,156,910 (157)

Taurochenodeoxycholic acid ameliorates liver fibrosis by regulating gut microbiota and bile acids via hippo-YAP pathway

open access: yesiScience
Summary: Cholestatic liver disease is characterized by gut microbiota dysbiosis and excessive toxic hepatic bile acid accumulation. Regulation of gut microbiota and suppression of bile acid synthesis are potential strategies for the treatment of ...
Lisheng Zhang   +4 more
doaj   +1 more source

Sequential Wnt Agonist Then Antagonist Treatment Accelerates Tissue Repair and Minimizes Fibrosis

open access: yesiScience, 2020
Summary: Tissue fibrosis compromises organ function and occurs as a potential long-term outcome in response to acute tissue injuries. Currently, lack of mechanistic understanding prevents effective prevention and treatment of the progression from acute ...
Xiao-Jun Tian   +7 more
doaj   +1 more source

Allicin Regulates Energy Homeostasis through Brown Adipose Tissue

open access: yesiScience, 2020
Summary: Brown adipose tissue (BAT) is a promising potential therapeutic target for the treatment of obesity and related metabolic diseases. Allicin, a natural product in garlic, has multiple biological and pharmacological functions. However, the role of
Chuanhai Zhang   +13 more
doaj   +1 more source

Type III adenylyl cyclase is essential for follicular development in female mice and their reproductive lifespan

open access: yesiScience
Summary: Premature ovarian failure (POF) is a complex and heterogeneous disease that causes infertility and subfertility. However, the molecular mechanism of POF has not been fully elucidated.
Baofang Zheng   +8 more
doaj   +1 more source

Dissecting semi-specialist and specialist plant biomass utilization strategies using the fungi Trichoderma reesei and Podospora anserina [PDF]

open access: yes, 2018
Fungi are the most important and efficient plant biomass degrading microorganisms and use different strategies to degrade plant biomass, reflecting their ecological niches.
Benocci, Tiziano   +1 more
core  

Combined transcriptome and translatome analyses reveal a role for tryptophan dependent auxin biosynthesis in the control of DOG1 dependent seed dormancy [PDF]

open access: yes, 2017
Transcriptome and translatome analyses of 6 and 24 hours imbibed seeds dormant and non-dormant seeds of NILDOG1-Cvi with and without addition of the transcription inhibitor Cordycepin.
Ljung, Karin   +13 more
core   +1 more source

Frontiers in Physiology

open access: yes, 2020
Frontiers in Physiology is a leading journal in its field, publishing rigorously peer-reviewed research on the physiology of living systems, from the subcellular and molecular domains to the intact organism, and its interaction with the ...
Petracci M.
core   +1 more source

Metabolic Adaptation, a Specialized Leaf Organ Structure and Vascular Responses to Diurnal N2 Fixation by Nostoc azollae Sustain the Astonishing Productivity of Azolla Ferns without Nitrogen Fertilizer [PDF]

open access: yes, 2017
Sustainable agriculture demands reduced input of man-made nitrogen (N) fertilizer, yet N2 fixation limits the productivity of crops with heterotrophic diazotrophic bacterial symbionts.
Werf, Adrie, van der   +32 more
core   +2 more sources

Niclosamide suppresses gastric cancer progression through YTHDF2 inhibition-affected lactate metabolic reprogramming

open access: yesiScience
Summary: Gastric cancer (GC), a highly aggressive tumor with significant mortality, exhibits metabolic reprogramming involving glucose, lipid, and amino acid metabolism.
Mosheng Tang   +18 more
doaj   +1 more source

Physiology

open access: yes, 1983
v.1165 hal.; 27 ...
Physiology
core  

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