Results 51 to 60 of about 642,316 (296)

Molecular Physiology of Kainate Receptors [PDF]

Physiological Reviews, 2001
A decade ago, our understanding of the molecular properties of kainate receptors and their involvement in synaptic physiology was essentially null. A plethora of recent studies has altered this situation profoundly such that kainate receptors are now regarded as key players in the modulation of transmitter release, as important mediators of the ...
Lerma Gómez, Juan, Paternain, Ana V., Rodríguez-Moreno, Antonio, López-García, Juan C.   +3 more
openaire   +3 more sources

Adult-Onset Myopathy with Constitutive Activation of Akt following the Loss of hnRNP-U

iScience, 2020
Summary: Skeletal muscle has the remarkable ability to modulate its mass in response to changes in nutritional input, functional utilization, systemic disease, and age.
Debalina Bagchi, Benjamin D. Mason, Kodilichi Baldino, Bin Li, Eun-Joo Lee, Yuteng Zhang, Linh Khanh Chu, Sherif El Raheb, Indranil Sinha, Ronald L. Neppl   +9 more
doaj   +1 more source

The sinusoidal hematopoietic niche is formed by Jam1a via Notch signaling in the zebrafish kidney

iScience, 2023
Summary: The zebrafish is a unique model to understand hematopoietic niches as hematopoietic stem/progenitor cells are maintained in the kidney. However, little is known about which cell types in the kidney play a role in hematopoietic niches.
Mao Kondo, Koki Kimura, Jingjing Kobayashi-Sun, Shiori Yamamori, Makoto Taniguchi, David Traver, Isao Kobayashi   +6 more
doaj   +1 more source

Molecular physiology of vision

Nippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics, 2003
Visual sensation results initially from light-induced isomerization of 11-cis-retinal in rhodopsin and cone pigments of photoreceptor cells. This transformation triggers cascades of events, i.e., activation of transducin and cGMP photodiesterase, decrease of cGMP, closure of cGMP-gated channels, and generation of active potential.
openaire   +3 more sources

The molecular physiology of CRAC channels [PDF]

Immunological Reviews, 2009
Summary:  The Ca2+release‐activated Ca2+ (CRAC) channel is a highly Ca2+‐selective store‐operated channel expressed in T cells, mast cells, and various other tissues. CRAC channels regulate critical cellular processes such as gene expression, motility, and the secretion of inflammatory mediators.
openaire   +2 more sources

Functional Validation of Two Fungal Subfamilies in Carbohydrate Esterase Family 1 by Biochemical Characterization of Esterases From Uncharacterized Branches [PDF]

, 2020
The fungal members of Carbohydrate Esterase family 1 (CE1) from the CAZy database include both acetyl xylan esterases (AXEs) and feruloyl esterases (FAEs). AXEs and FAEs are essential auxiliary enzymes to unlock the full potential of feedstock.
de Vries, Ronald P., Kabel, Mirjam A, Langeveld, Sandra, Molecular Plant Physiology, Underlin, Emilie N., Sub Molecular Plant Physiology, Kabel, Mirjam A., de Vries, Ronald P, Underlin, Emilie Nørmølle, Dilokpimol, Adiphol; id_orcid, Li, Xinxin, Griffin, Kelli, Frommhagen, Matthias, Underlin, Emilie N, Dilokpimol, Adiphol   +14 more
core   +1 more source

Hepatic Levels of DHA-Containing Phospholipids Instruct SREBP1-Mediated Synthesis and Systemic Delivery of Polyunsaturated Fatty Acids

iScience, 2020
Summary: Polyunsaturated fatty acids (PUFAs), such as docosahexaenoic acid (DHA) and arachidonic acid (ARA), play fundamental roles in mammalian physiology.
Daisuke Hishikawa, Keisuke Yanagida, Katsuyuki Nagata, Ayumi Kanatani, Yoshiko Iizuka, Fumie Hamano, Megumi Yasuda, Tadashi Okamura, Hideo Shindou, Takao Shimizu   +9 more
doaj   +1 more source

Global-run on sequencing identifies Gm11967 as an Akt-dependent long noncoding RNA involved in insulin sensitivity

iScience, 2022
Summary: The insulin responsive Akt and FoxO1 signaling axis is a key regulator of the hepatic transcriptional response to nutrient intake. Here, we used global run-on sequencing (GRO-seq) to measure the nascent transcriptional response to fasting and ...
Dominic Santoleri, Hee-Woong Lim, Matthew J. Emmett, Julian Stoute, Matthew J. Gavin, Jaimarie Sostre-Colón, Kahealani Uehara, Jaclyn E. Welles, Kathy Fange Liu, Mitchell A. Lazar, Paul M. Titchenell   +10 more
doaj   +1 more source

Exploring the role of grafting in abiotic stress management: Contemporary insights and automation trends

Plant Direct
Grafting is a technique that involves attaching a rootstock to the aerial part of another genotype or species (scion), leading to improved crop performance and sustainable growth.
Kaukab Razi, Preethika Suresh, Pritam Paramguru Mahapatra, Musa Al Murad, Ajila Venkat, Michitaka Notaguchi, Dong Won Bae, Muthu Arjuna Samy Prakash, Sowbiya Muneer   +8 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source