Results 31 to 40 of about 4,156,910 (157)

Depletion of cardiac cardiolipin synthase alters systolic and diastolic function

open access: yesiScience, 2021
Summary: Cardiolipin (CL) is a major cardiac mitochondrial phospholipid maintaining regular mitochondrial morphology and function in cardiomyocytes. Cardiac CL production includes its biosynthesis and a CL remodeling process.
Elia Smeir   +13 more
doaj   +1 more source

Effect of diet and genotype on the miRNome of mice with altered lipoprotein metabolism

open access: yesiScience, 2023
Summary: The molecular mechanism by which lipid/lipoprotein biosynthesis is regulated in mammals involves a very large number of genes that are subject to multiple levels of regulation.
Marco Busnelli   +7 more
doaj   +1 more source

Gene expression plasticity in Pocillopora corals from 2 locations on the Carrizales Reef, Pacific coast of Mexico

open access: yesCiencias Marinas, 2020
The greatest threat scleractinian corals face today is accelerated climate change. Assuming that most scleractinians are incapable of genetic adaptation to rapid global changes, the alternative response would be phenotypic plasticity, which is ...
M Alejandro Delgadillo-Nuño   +4 more
doaj   +1 more source

Ovarian tumorB1-mediated heat shock transcription factor 1 deubiquitination is critical for glycolysis and development of endometriosis

open access: yesiScience, 2022
Summary: Endometriosis is a common chronic condition characterized by abnormal growth of the endometrium outside the uterus. Heat shock transcription factor 1 (HSF1) is a significant regulator of the proteotoxic stress response and plays an essential ...
Xi Ling   +9 more
doaj   +1 more source

Potential Fungi Isolated From Anti-biodegradable Chinese Medicine Residue to Degrade Lignocellulose [PDF]

open access: yes, 2022
Traditional Chinese medicine is one of the ancient medicines which is popular in Asian countries, among which the residue produced by the use of anti-biodegradables is endless, and causes significant adverse impacts on the environment.
Kang, Yingqian   +13 more
core   +2 more sources

MYCT1 alters the glycogen shunt by regulating selective translation of RACK1-mediated enzymes

open access: yesiScience, 2022
Summary: MYCT1 has been shown to function as a tumor suppressor in various tumors, but its role in metabolism has never been reported. Here, we showed that global inactivation of Myct1 in mice led to progressive accumulation of glycogen in the liver ...
Dong-Xue Ding   +3 more
doaj   +1 more source

Hepatic Levels of DHA-Containing Phospholipids Instruct SREBP1-Mediated Synthesis and Systemic Delivery of Polyunsaturated Fatty Acids

open access: yesiScience, 2020
Summary: Polyunsaturated fatty acids (PUFAs), such as docosahexaenoic acid (DHA) and arachidonic acid (ARA), play fundamental roles in mammalian physiology.
Daisuke Hishikawa   +9 more
doaj   +1 more source

Global-run on sequencing identifies Gm11967 as an Akt-dependent long noncoding RNA involved in insulin sensitivity

open access: yesiScience, 2022
Summary: The insulin responsive Akt and FoxO1 signaling axis is a key regulator of the hepatic transcriptional response to nutrient intake. Here, we used global run-on sequencing (GRO-seq) to measure the nascent transcriptional response to fasting and ...
Dominic Santoleri   +10 more
doaj   +1 more source

From lignocellulose to plastics: Knowledge transfer on the degradation approaches by fungi [PDF]

open access: yes, 2021
In this review, we argue that there is much to be learned by transferring knowledge from research on lignocellulose degradation to that on plastic. Plastic waste accumulates in the environment to hazardous levels, because it is inherently recalcitrant to
Riaz, Asad   +14 more
core   +2 more sources

Exploring the role of grafting in abiotic stress management: Contemporary insights and automation trends

open access: yesPlant Direct
Grafting is a technique that involves attaching a rootstock to the aerial part of another genotype or species (scion), leading to improved crop performance and sustainable growth.
Kaukab Razi   +8 more
doaj   +1 more source

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