Results 31 to 40 of about 1,247,695 (303)

Myofiber androgen receptor increases muscle strength mediated by a skeletal muscle splicing variant of Mylk4

iScience, 2021
Summary: Androgens have a robust effect on skeletal muscles to increase muscle mass and strength. The molecular mechanism of androgen/androgen receptor (AR) action on muscle strength is still not well known, especially for the regulation of sarcomeric ...
Iori Sakakibara, Yuta Yanagihara, Koichi Himori, Takashi Yamada, Hiroshi Sakai, Yuichiro Sawada, Hirotaka Takahashi, Noritaka Saeki, Hiroyuki Hirakawa, Atsushi Yokoyama, So-ichiro Fukada, Tatsuya Sawasaki, Yuuki Imai   +12 more
doaj   +1 more source

Mitochondrial behaviour throughout the lytic cycle of Toxoplasma gondii [PDF]

, 2017
Mitochondria distribution in cells controls cellular physiology in health and disease. Here we describe the mitochondrial morphology and positioning found in the different stages of the lytic cycle of the eukaryotic single-cell parasite Toxoplasma gondii.
Lemgruber, Leandro, Ovciarikova, Jana, Sheiner, Lilach, Stilger, Krista L., Sullivan, William J.   +4 more
core   +2 more sources

Molecular Physiology of Mammalian Glucokinase [PDF]

Cellular and Molecular Life Sciences, 2008
The glucokinase (GCK) gene was one of the first candidate genes to be identified as a human "diabetes gene". Subsequently, important advances were made in understanding the impact of GCK in the regulation of glucose metabolism. Structure elucidation by crystallography provided insight into the kinetic properties of GCK.
openaire   +4 more sources

Hepatic Levels of DHA-Containing Phospholipids Instruct SREBP1-Mediated Synthesis and Systemic Delivery of Polyunsaturated Fatty Acids

iScience, 2020
Summary: Polyunsaturated fatty acids (PUFAs), such as docosahexaenoic acid (DHA) and arachidonic acid (ARA), play fundamental roles in mammalian physiology.
Daisuke Hishikawa, Keisuke Yanagida, Katsuyuki Nagata, Ayumi Kanatani, Yoshiko Iizuka, Fumie Hamano, Megumi Yasuda, Tadashi Okamura, Hideo Shindou, Takao Shimizu   +9 more
doaj   +1 more source

Depletion of cardiac cardiolipin synthase alters systolic and diastolic function

iScience, 2021
Summary: Cardiolipin (CL) is a major cardiac mitochondrial phospholipid maintaining regular mitochondrial morphology and function in cardiomyocytes. Cardiac CL production includes its biosynthesis and a CL remodeling process.
Elia Smeir, Sarah Leberer, Annelie Blumrich, Georg Vogler, Anastasia Vasiliades, Sandra Dresen, Carsten Jaeger, Yoann Gloaguen, Christian Klose, Dieter Beule, P. Christian Schulze, Rolf Bodmer, Anna Foryst-Ludwig, Ulrich Kintscher   +13 more
doaj   +1 more source

The envenomation of general physiology throughout the last century. [PDF]

, 2017
Toxins are the poisonous products of organisms. Toxins serve vital defensive and offensive functions for those that harbor them: stinging scorpions, pesticidal plants, sanguinary snakes, fearless frogs, sliming snails, noxious newts, and smarting spiders.
Sack, Jon T
core   +1 more source

TRPC1 Regulates the Activity of a Voltage-Dependent Nonselective Cation Current in Hippocampal CA1 Neurons

Cells, 2020
The cation channel subunit TRPC1 is strongly expressed in central neurons including neurons in the CA1 region of the hippocampus where it forms complexes with TRPC4 and TRPC5.
Frauke Kepura, Eva Braun, Alexander Dietrich, Tim D. Plant   +3 more
doaj   +1 more source

Effect of diet and genotype on the miRNome of mice with altered lipoprotein metabolism

iScience, 2023
Summary: The molecular mechanism by which lipid/lipoprotein biosynthesis is regulated in mammals involves a very large number of genes that are subject to multiple levels of regulation.
Marco Busnelli, Stefano Manzini, Alice Colombo, Elsa Franchi, Matteo Chiara, Gaia Zaffaroni, David Horner, Giulia Chiesa   +7 more
doaj   +1 more source

Delivery of Functionality in Complex Food Systems: Physically Inspired Approaches from Nanoscale to Microscale, Wageningen 18-21 October 2009 [PDF]

, 2010
The Wageningen Delivery of Functionality symposium covered all aspects involved with food structural design to arrive at high-quality foods which meet demanding customer expectations and regulatory requirements.
Duchateau, G., Linden, E., van der, Ubbink, J.   +2 more
core   +2 more sources

Trace Element Management in Rice

Agronomy, 2015
Trace elements (TEs) are vital for the operation of metabolic pathways that promote growth and structural integrity. Paddy soils are often prone to TE limitation due to intensive cultivation and irrigation practices.
Abin Sebastian, Majeti Narasimha Vara Prasad   +1 more
doaj   +1 more source