Results 11 to 20 of about 4,368,802 (298)

Molecular imaging with engineered physiology

open access: yesNature Communications, 2016
The vasculature produces strong endogenous contrast in magnetic resonance imaging (MRI). Here Desai et al. report genetically encoded imaging probes derived from the vasodilator, calcitonin gene-related peptide, which allows visualization of molecular ...
Mitul Desai   +4 more
doaj   +5 more sources

Molecular physiology of water balance. [PDF]

open access: yesN Engl J Med, 2015
In this article, the authors review the classic, integrative principles of water balance. They use this model to discuss the role of underlying genes and gene products (proteins) in water balance and to provide a mechanistic basis for decisions about related disorders.
Knepper MA, Kwon TH, Nielsen S.
europepmc   +6 more sources

Molecular Physiology of the Neuronal Synapse. [PDF]

open access: yesCurr Issues Mol Biol
Neuronal synapses are the functional units of communication in the central nervous system. This review describes the molecular mechanisms regulating synaptic transmission, plasticity, and circuit refinement. At the presynaptic active zone, scaffolding proteins including bassoon, piccolo, RIMs, and munc13 organize vesicle priming and the localization of
Ramírez-Expósito MJ   +2 more
europepmc   +3 more sources

Plant Stress Physiology [PDF]

open access: yes, 2022
This book includes ten chapters addressing various aspects of plant stress physiology, including plant responses and tolerance to abiotic and biotic stress.

core   +1 more source

Molecular exercise physiology

open access: yes, 2017
Abstract Molecular exercise physiology is the study of exercise physiology using molecular biology methods. The development of differentiated cell types is regulated by transcription factors like the muscle-making MyoD that specifies cell type, while others regulate the development of muscle, tendons, and bones.
Henning Wackerhage   +2 more
openaire   +2 more sources

The molecular physiology of CRH neurons. [PDF]

open access: yesFront Neuroendocrinol, 2012
Corticotropin releasing hormone (CRH) is essential for stress adaptation by mediating hypothalamic-pituitary-adrenal (HPA) axis, behavioral and autonomic responses to stress. Activation of CRH neurons depends on neural afferents from the brain stem and limbic system, leading to sequential CRH release and synthesis.
Aguilera G, Liu Y.
europepmc   +4 more sources

Prominin 1 and Notch regulate ciliary length and dynamics in multiciliated cells of the airway epithelium

open access: yesiScience, 2022
Summary: Differences in ciliary morphology and dynamics among multiciliated cells of the respiratory tract contribute to efficient mucociliary clearance. Nevertheless, little is known about how these phenotypic differences are established.
Carlos F.H. Serra   +5 more
doaj   +1 more source

Primary Cell Culture as a Model System for Evolutionary Molecular Physiology. [PDF]

open access: yesInt J Mol Sci
Primary cell culture is a powerful model system to address fundamental questions about organismal physiology at the cellular level, especially for species that are difficult, or impossible, to study under natural or semi-natural conditions.
Harper JM.
europepmc   +2 more sources

Alteration of lipid bilayer mechanics by volatile anesthetics: Insights from μs-long molecular dynamics simulations

open access: yesiScience, 2022
Summary: Very few drugs in clinical practice feature the chemical diversity, narrow therapeutic window, unique route of administration, and reversible cognitive effects of volatile anesthetics.
Eric A. Zizzi   +3 more
doaj   +1 more source

A Drosophila platform identifies a novel, personalized therapy for a patient with adenoid cystic carcinoma

open access: yesiScience, 2021
Summary: Adenoid cystic carcinoma (ACC) is a rare cancer type that originates in the salivary glands. Tumors commonly invade along nerve tracks in the head and neck, making surgery challenging.
Erdem Bangi   +29 more
doaj   +1 more source

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