Results 21 to 30 of about 4,156,910 (157)

Celecoxib alleviates pathological cardiac hypertrophy and fibrosis via M1-like macrophage infiltration in neonatal mice

open access: yesiScience, 2021
Summary: Cardiac hypertrophy is an adaptive response to all forms of heart disease, including hypertension, myocardial infarction, and cardiomyopathy. Cyclooxygenase-2 (COX-2) overexpression results in inflammatory response, cardiac cell apoptosis, and ...
Yanli Zhao   +6 more
doaj   +1 more source

The Arabidopsis DELAY OF GERMINATION 1 gene affects ABSCISIC ACID INSENSITIVE 5 (ABI5) expression and genetically interacts with ABI3 during Arabidopsis seed development [PDF]

open access: yes, 2016
The seed expressed gene DELAY OF GERMINATION (DOG) 1 is absolutely required for the induction of dormancy. Next to a non-dormant phenotype, the dog1-1 mutant is also characterized by a reduced seed longevity suggesting that DOG1 may affect additional ...
Willems, L.A.J.   +9 more
core   +2 more sources

Effects of parental temperature and nitrate on seed performance are reflected by partly overlapping genetic and metabolic pathways [PDF]

open access: yes, 2016
Seed performance is affected by the seed maturation environment, and previously we have shown that temperature, nitrate and light intensity were the most influential environmental factors affecting seed performance.
Willems, Leo A.J.   +13 more
core   +2 more sources

Trace Element Management in Rice

open access: yesAgronomy, 2015
Trace elements (TEs) are vital for the operation of metabolic pathways that promote growth and structural integrity. Paddy soils are often prone to TE limitation due to intensive cultivation and irrigation practices.
Abin Sebastian   +1 more
doaj   +1 more source

NFIA determines the cis-effect of genetic variation on Ucp1 expression in murinethermogenic adipocytes

open access: yesiScience, 2022
Summary: Thermogenic brown and beige adipocytes counteract obesity by enhancing energy dissipation via uncoupling protein-1 (Ucp1). However, the effect of genetic variation on these cells, a major source of disease susceptibility, has been less well ...
Yuta Hiraike   +17 more
doaj   +1 more source

Sugar signals and the control of plant growth and development [PDF]

open access: yes, 2014
Sugars have a central regulatory function in steering plant growth. This review focuses on information presented in the past 2 years on key players in sugar-mediated plant growth regulation, with emphasis on trehalose 6-phosphate, target of rapamycin ...
Lastdrager, Jeroen,   +7 more
core   +1 more source

Evidence for ligninolytic activity of the ascomycete fungus Podospora anserina [PDF]

open access: yes, 2020
Background The ascomycete fungus Podospora anserina has been appreciated for its targeted carbohydrate-active enzymatic arsenal. As a late colonizer of herbivorous dung, the fungus acts specifically on the more recalcitrant fraction of lignocellulose and
De Vries, Ronald P.   +10 more
core   +2 more sources

TRPC1 Regulates the Activity of a Voltage-Dependent Nonselective Cation Current in Hippocampal CA1 Neurons

open access: yesCells, 2020
The cation channel subunit TRPC1 is strongly expressed in central neurons including neurons in the CA1 region of the hippocampus where it forms complexes with TRPC4 and TRPC5.
Frauke Kepura   +3 more
doaj   +1 more source

Macroalgae Derived Fungi Have High Abilities to Degrade Algal Polymers [PDF]

open access: yes, 2019
Marine fungi associated with macroalgae are an ecologically important group that have a strong potential for industrial applications. In this study, twenty-two marine fungi isolated from the brown seaweed Fucus sp.
De Vries, Ronald P.   +8 more
core   +1 more source

Myofiber androgen receptor increases muscle strength mediated by a skeletal muscle splicing variant of Mylk4

open access: yesiScience, 2021
Summary: Androgens have a robust effect on skeletal muscles to increase muscle mass and strength. The molecular mechanism of androgen/androgen receptor (AR) action on muscle strength is still not well known, especially for the regulation of sarcomeric ...
Iori Sakakibara   +12 more
doaj   +1 more source

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