Results 21 to 30 of about 1,247,695 (303)

JUNGBRUNNEN1 confers drought tolerance downstream of the HD-Zip I Transcription factor AtHB13 [PDF]

open access: yes, 2017
Low water availability is the major environmental factor limiting growth and productivity of plants and crops and is therefore considered of high importance for agriculture affected by climate change.
Allu, Annapurna D.   +6 more
core   +1 more source

NFIA determines the cis-effect of genetic variation on Ucp1 expression in murinethermogenic adipocytes

open access: yesiScience, 2022
Summary: Thermogenic brown and beige adipocytes counteract obesity by enhancing energy dissipation via uncoupling protein-1 (Ucp1). However, the effect of genetic variation on these cells, a major source of disease susceptibility, has been less well ...
Yuta Hiraike   +17 more
doaj   +1 more source

The Mitochondrial Ca(2+) Uniporter: Structure, Function, and Pharmacology. [PDF]

open access: yes, 2017
Mitochondrial Ca(2+) uptake is crucial for an array of cellular functions while an imbalance can elicit cell death. In this chapter, we briefly reviewed the various modes of mitochondrial Ca(2+) uptake and our current understanding of mitochondrial Ca(2+)
A Quintana   +167 more
core   +2 more sources

Oxytocin promotes hepatic regeneration in elderly mice

open access: yesiScience, 2021
Summary: Liver aging impairs the ability of hepatocyte regeneration. Recent studies have found that oxytocin (OT) plays an important role in promoting tissue repair and maintaining differentiation and regeneration of stem cells. Here, we reported that OT
Dan Luo   +6 more
doaj   +1 more source

Circadian rhythms and hormonal homeostasis: Pathophysiological implications [PDF]

open access: yes, 2017
Over recent years, a deeper comprehension of the molecular mechanisms that control biological clocks and circadian rhythms has been achieved. In fact, many studies have contributed to unravelling the importance of the molecular clock for the regulation ...
Bruscalupi, Giovannella, Gnocchi, Davide
core   +2 more sources

Propionate induces intestinal oxidative stress via Sod2 propionylation in zebrafish

open access: yesiScience, 2021
Summary: Propionate and propionyl-CoA accumulation have been associated with the development of mitochondrial dysfunction. In this study, we show that propionate induces intestinal damage in zebrafish when fed a high-fat diet (HFD). The intestinal damage
Qianwen Ding   +10 more
doaj   +1 more source

DNA looping: the consequences and its control [PDF]

open access: yes, 2006
The formation of DNA loops by proteins and protein complexes is ubiquitous to many fundamental cellular processes, including transcription, recombination, and replication.
Ackers   +45 more
core   +1 more source

The dual nature of trehalose in citrus canker disease: A virulence factor for Xanthomonas citri subsp. citri and a trigger for plant defence responses [PDF]

open access: yes, 2015
Xanthomonas citri subsp. citri (Xcc) is a bacterial pathogen that causes citrus canker in susceptible Citrus spp. The Xcc genome contains genes encoding enzymes from three separate pathways of trehalose biosynthesis.
Feil, Regina   +10 more
core   +1 more source

Hsp70 in mitochondrial biogenesis [PDF]

open access: yes, 1994
The family of hsp70 (70 kilodalton heat shock protein) molecular chaperones plays an essential and diverse role in cellular physiology, Hsp70 proteins appear to elicit their effects by interacting with polypeptides that present domains which exhibit non ...
A. Tzagoloff   +53 more
core   +1 more source

Adult-Onset Myopathy with Constitutive Activation of Akt following the Loss of hnRNP-U

open access: yesiScience, 2020
Summary: Skeletal muscle has the remarkable ability to modulate its mass in response to changes in nutritional input, functional utilization, systemic disease, and age.
Debalina Bagchi   +9 more
doaj   +1 more source

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