Results 41 to 50 of about 4,156,910 (157)

Adult-Onset Myopathy with Constitutive Activation of Akt following the Loss of hnRNP-U

open access: yesiScience, 2020
Summary: Skeletal muscle has the remarkable ability to modulate its mass in response to changes in nutritional input, functional utilization, systemic disease, and age.
Debalina Bagchi   +9 more
doaj   +1 more source

Type 2 diabetes sex-specific effects associated with E167K coding variant in TM6SF2

open access: yesiScience, 2021
Summary: The rs58542926C >T (E167K) variant of the transmembrane 6 superfamily member 2 gene (TM6SF2) is associated with increased risks for nonalcoholic fatty liver disease (NAFLD) and type 2 diabetes (T2D).
Yanbo Fan   +24 more
doaj   +1 more source

The role of trehalose metabolism in plant growth and stress responses [PDF]

open access: yes, 2012
This thesis started with defining plant stress resilience and its societal significance in Chapter 1. We realized that not just the absolute yield matters to farmers but rather the predictability of the yield given the agricultural practices in the socio-
Sedijani, P.   +2 more
core   +1 more source

The sinusoidal hematopoietic niche is formed by Jam1a via Notch signaling in the zebrafish kidney

open access: yesiScience, 2023
Summary: The zebrafish is a unique model to understand hematopoietic niches as hematopoietic stem/progenitor cells are maintained in the kidney. However, little is known about which cell types in the kidney play a role in hematopoietic niches.
Mao Kondo   +6 more
doaj   +1 more source

Gene regulation in seeds: insights into translational dynamics [PDF]

open access: yes, 2016
Seeds are unique structures in the plant life cycle. The variation in the timing of seed maturation, dispersion, and the establishment of seed dormancy and longevity, increases the chances of plant survival and enlarge the distance that plants could ...
Bai, B.   +2 more
core  

Seed dormancy and seed longevity: from genetic variation to gene identification [PDF]

open access: yes, 2014
Seed dormancy and seed longevity are the most important survival traits in the soil seed bank. Both traits are induced during seed maturation and evolved to assure seed survival during environmental conditions that cannot support the regular course of ...
Nguyen, T.P.   +2 more
core  

Aging-Associated Extracellular Vesicles Contain Immune Regulatory microRNAs Alleviating Hyperinflammatory State and Immune Dysfunction in the Elderly

open access: yesiScience, 2020
Summary: Aging-associated changes in the immune system often lead to immune dysfunction; however, the mechanisms that underlie this phenomenon have yet to be fully elucidated. This study found that the microRNA-192 (miR-192) is an aging-associated immune
Hirotake Tsukamoto   +2 more
doaj   +1 more source

Control of plant architecture by distinctive TALE homeobox gene interactions [PDF]

open access: yes, 2009
In eukaryotes, transcription factor (TF)-based network is a widely used mechanism to regulate fundamental developmental processes. Both animals and plants utilize three-amino-acid-loop-extension (TALE) homeodomain (HD) transcription factors to subdivide ...
Molecular Plant Physiology   +2 more
core   +1 more source

The role of Phe150 in human voltage-gated proton channel

open access: yesiScience, 2022
Summary: The voltage-gated proton channel Hv1 is a member of voltage-gated ion channels containing voltage-sensing domains (VSDs). The VSDs are made of four membrane-spanning segments (S1 through S4), and their function is to detect changes in membrane ...
Xin Wu, Lu Zhang, Liang Hong
doaj   +1 more source

Fructose and glucose signaling in Arabidopsis thaliana [PDF]

open access: yes, 2012
All life on earth depends on photosynthesis, a process by which energy from sunlight is used to convert water and carbon dioxide into sugars and oxygen. In plants, sugars are used as building blocks for growth, energy and transport.
Wind, J.J.   +2 more
core   +1 more source

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