Results 41 to 50 of about 642,316 (296)

The Arabidopsis DELAY OF GERMINATION 1 gene affects ABSCISIC ACID INSENSITIVE 5 (ABI5) expression and genetically interacts with ABI3 during Arabidopsis seed development [PDF]

, 2016
The seed expressed gene DELAY OF GERMINATION (DOG) 1 is absolutely required for the induction of dormancy. Next to a non-dormant phenotype, the dog1-1 mutant is also characterized by a reduced seed longevity suggesting that DOG1 may affect additional ...
Willems, L.A.J., Raijou, G., Cueff, Gwendal, Hilhorst, H.W.M., Bentsink, L., Hanson, S.J., Jamar, D.C.L., Molecular Plant Physiology, Sub Molecular Plant Physiology, Dekkers, B.J.W.   +9 more
core   +1 more source

NFIA determines the cis-effect of genetic variation on Ucp1 expression in murinethermogenic adipocytes

iScience, 2022
Summary: Thermogenic brown and beige adipocytes counteract obesity by enhancing energy dissipation via uncoupling protein-1 (Ucp1). However, the effect of genetic variation on these cells, a major source of disease susceptibility, has been less well ...
Yuta Hiraike, Shuichi Tsutsumi, Takahito Wada, Misato Oguchi, Kaede Saito, Masahiro Nakamura, Satoshi Ota, Michinori Koebis, Harumi Nakao, Atsu Aiba, Gaku Nagano, Haruya Ohno, Kenji Oki, Masayasu Yoneda, Takashi Kadowaki, Hiroyuki Aburatani, Hironori Waki, Toshimasa Yamauchi   +17 more
doaj   +1 more source

TRPC1 Regulates the Activity of a Voltage-Dependent Nonselective Cation Current in Hippocampal CA1 Neurons

Cells, 2020
The cation channel subunit TRPC1 is strongly expressed in central neurons including neurons in the CA1 region of the hippocampus where it forms complexes with TRPC4 and TRPC5.
Frauke Kepura, Eva Braun, Alexander Dietrich, Tim D. Plant   +3 more
doaj   +1 more source

Myofiber androgen receptor increases muscle strength mediated by a skeletal muscle splicing variant of Mylk4

iScience, 2021
Summary: Androgens have a robust effect on skeletal muscles to increase muscle mass and strength. The molecular mechanism of androgen/androgen receptor (AR) action on muscle strength is still not well known, especially for the regulation of sarcomeric ...
Iori Sakakibara, Yuta Yanagihara, Koichi Himori, Takashi Yamada, Hiroshi Sakai, Yuichiro Sawada, Hirotaka Takahashi, Noritaka Saeki, Hiroyuki Hirakawa, Atsushi Yokoyama, So-ichiro Fukada, Tatsuya Sawasaki, Yuuki Imai   +12 more
doaj   +1 more source

Depletion of cardiac cardiolipin synthase alters systolic and diastolic function

iScience, 2021
Summary: Cardiolipin (CL) is a major cardiac mitochondrial phospholipid maintaining regular mitochondrial morphology and function in cardiomyocytes. Cardiac CL production includes its biosynthesis and a CL remodeling process.
Elia Smeir, Sarah Leberer, Annelie Blumrich, Georg Vogler, Anastasia Vasiliades, Sandra Dresen, Carsten Jaeger, Yoann Gloaguen, Christian Klose, Dieter Beule, P. Christian Schulze, Rolf Bodmer, Anna Foryst-Ludwig, Ulrich Kintscher   +13 more
doaj   +1 more source

Effect of diet and genotype on the miRNome of mice with altered lipoprotein metabolism

iScience, 2023
Summary: The molecular mechanism by which lipid/lipoprotein biosynthesis is regulated in mammals involves a very large number of genes that are subject to multiple levels of regulation.
Marco Busnelli, Stefano Manzini, Alice Colombo, Elsa Franchi, Matteo Chiara, Gaia Zaffaroni, David Horner, Giulia Chiesa   +7 more
doaj   +1 more source

Trace Element Management in Rice

Agronomy, 2015
Trace elements (TEs) are vital for the operation of metabolic pathways that promote growth and structural integrity. Paddy soils are often prone to TE limitation due to intensive cultivation and irrigation practices.
Abin Sebastian, Majeti Narasimha Vara Prasad   +1 more
doaj   +1 more source

Ovarian tumorB1-mediated heat shock transcription factor 1 deubiquitination is critical for glycolysis and development of endometriosis

iScience, 2022
Summary: Endometriosis is a common chronic condition characterized by abnormal growth of the endometrium outside the uterus. Heat shock transcription factor 1 (HSF1) is a significant regulator of the proteotoxic stress response and plays an essential ...
Xi Ling, Jiayi Lu, Xiaoyun Wang, Lan Liu, Lu Liu, Yadi Wang, Yujun Sun, Chune Ren, Chao Lu, Zhenhai Yu   +9 more
doaj   +1 more source

Gene expression plasticity in Pocillopora corals from 2 locations on the Carrizales Reef, Pacific coast of Mexico

Ciencias Marinas, 2020
The greatest threat scleractinian corals face today is accelerated climate change. Assuming that most scleractinians are incapable of genetic adaptation to rapid global changes, the alternative response would be phenotypic plasticity, which is ...
M Alejandro Delgadillo-Nuño, Marco A Liñán-Cabello, Erick Delgadillo-Nuño, Clara E Galindo-Sánchez, Eugenio de Jesús Carpizo-Ituarte   +4 more
doaj   +1 more source

MYCT1 alters the glycogen shunt by regulating selective translation of RACK1-mediated enzymes

iScience, 2022
Summary: MYCT1 has been shown to function as a tumor suppressor in various tumors, but its role in metabolism has never been reported. Here, we showed that global inactivation of Myct1 in mice led to progressive accumulation of glycogen in the liver ...
Dong-Xue Ding, Yue Wang, Wei Yan, Wei-Neng Fu   +3 more
doaj   +1 more source