Advancing Clinical Medicine with Raman Spectroscopy: Current Trends and Future Perspectives
Advanced Photonics ResearchThis review explores the potential of Raman spectroscopy and microscopy (RS) in clinical medicine, focusing on the diagnostic and therapeutic applications across multiple disciplines. For example, RS has proven effective in distinguishing between healthy
Jiří Bufka +5 more
doaj +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Molecular Nanomagnets with Photomagnetic Properties: Design Strategies and Recent Advances
The magnetic properties of molecular nanomagnets can be finely modulated by light, which provides great potential in optical switches, smart sensors, and data storage devices.
Wei Shi +3 more
core +1 more source
Molecular and nanostructural mechanisms of deformation, strength and toughness of spider silk fibrils [PDF]
, 2010 Spider silk is one of the strongest, most extensible and toughest biological materials known, exceeding the properties of many engineered materials including steel.
Keten, S. +15 more
core +1 more source
BERTology of Molecular Property Prediction
CoRRChemical language models (CLMs) have emerged as promising competitors to popular classical machine learning models for molecular property prediction (MPP) tasks. However, an increasing number of studies have reported inconsistent and contradictory results for the performance of CLMs across various MPP benchmark tasks.
Mohammad Mostafanejad +2 more
openaire +3 more sources
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
High and low molecular weight crossovers in the longest relaxation time dependence of linear cis-1,4 polyisoprene by dielectric relaxations [PDF]
, 2010 The dielectric relaxation of cis-1,4 Polyisoprene [PI] is sensitive not only to the local and segmental dynamics but also to the larger scale chain (end-to-end) fluctuations.
Alegría, Angel +4 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Molecular Dynamics Simulations of Lead and Lithium in Liquid Phase [PDF]
, 2011 Pb17Li is today a reference breeder material in diverse fusion R&D programs worldwide. Extracting dynamic and structural properties of liquid LiPb mixtures via molecular dynamics simulations, represent a crucial step for multiscale modeling efforts ...
Fraile García, Alberto +5 more
core +1 more source
FP2VEC: a new molecular featurizer for learning molecular properties
Bioinformatics, 2019 Abstract Motivation One of the most successful methods for predicting the properties of chemical compounds is the quantitative structure–activity relationship (QSAR) methods. The prediction accuracy of QSAR models has recently been greatly improved by employing deep learning technology.
Woosung Jeon, Dongsup Kim
openaire +2 more sources