Results 61 to 70 of about 10,169,709 (296)
Biotechnology & Biotechnological Equipment, 2021 The combination drug menadione/ascorbate (M/A) manifests synergistic dose-dependent antiproliferative and cytotoxic effects towards cancer cells, but not towards normal cells of the same origin especially at concentrations that can be achieved in vivo by
Severina Semkova +6 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
International Journal of Electrochemical Science, 2012 Quantum chemical calculations using the Density Functional Theory (DFT) method at three different basis sets, namely, 6-31(d,p), 6-31+(d,p) and 6-311G(d,p) were performed on selected triazole and benzimidazole derivatives, namely 2-aminobenzimidazole ...
Mwadham M. Kabanda +6 more
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Prediction of Molecular Properties Using Molecular Topographic Map
Molecules, 2021 Prediction of molecular properties plays a critical role towards rational drug design. In this study, the Molecular Topographic Map (MTM) is proposed, which is a two-dimensional (2D) map that can be used to represent a molecule.
Atsushi Yoshimori
doaj +1 more source
Some Molecular Properties of Rhodanese
Journal of Biological Chemistry, 1970 Abstract Fluorescence studies of crystalline bovine liver rhodanese indicate that the reactive sulfhydryl group is in a region which can participate in hydrophobic (apolar) interactions. Fluorescence polarization studies confirm that rhodanese exists in a mobile monomer-dimer equilibrium.
P, Horowitz, J, Westley
openaire +2 more sources
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Molecular modeling for physical property prediction [PDF]
, 2006 Multiscale modeling is becoming the standard approach for process study in a broader framework that promotes computer aided integrated product and process design.
Joulia, Xavier, Gerbaud, Vincent
core
Scientific Reports, 2021 The bacteriocidal properties of silver nanoparticles (AgNPs) depend on their average diameter (toxicity increases with decreasing diameter). In the present work, we describe novel green chemistry biosynthesis of AgNPs from AgNO3 added to cell-free ...
Ameni Kthiri +5 more
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source