Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen+12 more
wiley +1 more source
Molecular recognition of the atypical chemokine-like peptide GPR15L by its cognate receptor GPR15. [PDF]
Zhang Z+6 more
europepmc +1 more source
The Role of Homophilic Binding in Anti-tumor Antibody R24 Recognition of Molecular Surfaces [PDF]
Marcin J. Kaminski+7 more
openalex +1 more source
Does Porphyromonas gingivalis truly inhibit the oral carcinogenesis?
Chen‐xi Li, Zhong‐cheng Gong
wiley +1 more source
Molecular Recognition between Carbon Dioxide and Biodegradable Hydrogel Models: A Density Functional Theory (DFT) Investigation. [PDF]
Carrascal-Hernandez DC+5 more
europepmc +1 more source
Detection of Unpredictable Molecular Recognition through Carbonyl-π Interaction in Poly(methyl acrylate)-Silica Hybrids1 [PDF]
Hirotaka Ihara+3 more
openalex +1 more source
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova+18 more
wiley +1 more source
Switching molecular recognition selectivities by temperature in a diffusion-regulatory porous material. [PDF]
Su Y+9 more
europepmc +1 more source
Alternate protein frameworks for molecular recognition.
Ja Hyeon Ku, Peter G. Schultz
openalex +1 more source
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma+9 more
wiley +1 more source