Results 101 to 110 of about 2,823,273 (337)

Digital gene expression analysis of the zebra finch genome [PDF]

, 2010
Background: In order to understand patterns of adaptation and molecular evolution it is important to quantify both variation in gene expression and nucleotide sequence divergence.
Balakrishnan, C.N., Burke, T., Ekblom, R., Slate , J.   +3 more
core   +4 more sources

Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice

FEBS Letters, EarlyView.
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász, Albert Bálint Papp, Lukács Sándor Lesinszki, Attila Mócsai, Tamás Varga, László Nagy, Péter Gogolák   +6 more
wiley   +1 more source

The transcriptional repressor complex FRS7-FRS12 regulates flowering time and growth in Arabidopsis [PDF]

, 2017
Most living organisms developed systems to efficiently time environmental changes. The plant-clock acts in coordination with external signals to generate output responses determining seasonal growth and flowering time.
De Clercq, Rebecca, De Jaeger, Geert, De Milde, Liesbeth, Dhondt, Stijn, Eeckhout, Dominique, Fernandez Calvo, Patricia, Gevaert, Kris, Goossens, Alain, Heyndrickx, Ken, Inzé, Dirk, Iñigo, Sabrina, Pauwels, Laurens, Ritter Traub, Andrés, Ron, Mily, Shi, Hua, Somers, David E, Vanden Bossche, Robin, Vandepoele, Klaas   +17 more
core   +2 more sources

Development of visible light‐sensitive human neuropsin (OPN5) via single amino acid substitution

FEBS Letters, EarlyView.
The present study determines a key amino acid residue, Lys91, for defining UV sensitivity of human OPN5. Heterologous action spectroscopy of the wild type and K91 mutants of OPN5 in HEK293T cells reveals that substitution of Lys91 with neutral (alanine) or acidic amino acids (glutamic or aspartic acids) causes substantial shifts in spectral sensitivity
Yusuke Sakai, Richard J. McDowell, Robert J. Lucas   +2 more
wiley   +1 more source

The Far-Infrared, UV and Molecular Gas Relation in Galaxies up to z=2.5

, 2012
We use the infrared excess (IRX) FIR/UV luminosity ratio to study the relation between the effective UV attenuation (A_IRX) and the UV spectral slope (beta) in a sample of 450 ...
Berta, S., Genzel, R., Lutz, D., Magnelli, B., Nordon, R., Poglitsch, A., Popesso, P., Rosario, D., Saintonge, A., Schreiber, N. M. Forster, Sturm, E., Tacconi, L. J., Wuyts, S.   +12 more
core   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

FEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan, Victoria Scarpelli, Marten Exterkate   +2 more
wiley   +1 more source

A topological approach for protein classification

, 2015
Protein function and dynamics are closely related to its sequence and structure. However prediction of protein function and dynamics from its sequence and structure is still a fundamental challenge in molecular biology.
Cang, Zixuan, Mu, Lin, Opron, Kristopher, Wei, Guo-Wei, Wu, Kedi, Xia, Kelin   +5 more
core   +1 more source

C‐mannosylation promotes ADAMTS1 activation and secretion in human testicular germ cell tumor NEC8 cells

FEBS Letters, EarlyView.
C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi, Takehiro Suzuki, Ryota Kawahara, Natsumi Harai, Naoshi Dohmae, Siro Simizu   +5 more
wiley   +1 more source

The multidrug and toxin extrusion (MATE) transporter DTX51 antagonizes non‐cell‐autonomous HLS1–AMP1 signaling in a region‐specific manner

FEBS Letters, EarlyView.
The Arabidopsis mutants hls1 hlh1 and amp1 lamp1 exhibit pleiotropic developmental phenotypes. Although the functions of the causative genes remain unclear, they act in the same genetic pathway and are thought to generate non‐cell‐autonomous signals.
Takashi Nobusawa, Makoto Kusaba
wiley   +1 more source

A combined molecular typing approach does not discriminate Legionella pneumophila serogroup 1 strains of a predominant sequence-based type in Palermo, Italy

Journal of Infection and Public Health, 2009
Summary: The sequence-based type 1,4,3,1,1,1 of Legionella pneumophila sg.1 is predominant in the Palermo city environment since several years. In this study, extended sequence-based typing and pulsed field gel electrophoresis were used in a combined ...
Celestino Bonura, Caterina Mammina, Antonietta Vella, Santina Belfiore, Alfredo Chiarini, Anna Giammanco   +5 more
doaj   +1 more source