Extracting Dwell Time Sequences from Processive Molecular Motor Data [PDF]
Processive molecular motors, such as kinesin, myosin, or dynein, convert chemical energy into mechanical energy by hydrolyzing ATP. The mechanical energy is used for moving in discrete steps along the cytoskeleton and carrying a molecular load. Single-molecule recordings of motor position along a substrate polymer appear as a stochastic staircase ...
Lorin S. Milescu+3 more
openalex +5 more sources
Impact of molecular sequence data completeness on HIV cluster detection and a network science approach to enhance detection. [PDF]
Mazrouee S+8 more
europepmc +3 more sources
Molecular phylogeny of Asian Meconopsis based on nuclear ribosomal and chloroplast DNA sequence data. [PDF]
The taxonomy and phylogeny of Asian Meconopsis (Himalayan blue poppy) remain largely unresolved. We used the internal transcribed spacer (ITS) region of nuclear ribosomal DNA (nrDNA) and the chloroplast DNA (cpDNA) trnL-F region for phylogenetic ...
Yu-Cheng Liu+3 more
doaj +5 more sources
A Model Information Management Plan for Molecular Pathology Sequence Data Using Standards [PDF]
Incorporating genetic variant data into the electronic health record (EHR) in discrete computable fashion has vexed the informatics community for years. Genetic sequence test results are typically communicated by the molecular laboratory and stored in the EHR as textual documents. Although text documents are useful for human readability and initial use,
W. Scott Campbell+7 more
openalex +4 more sources
Molecular Sequence Data of Hepatitis B Virus and Genetic Diversity After Vaccination [PDF]
The effect of vaccination programs on transmission of infectious disease is usually assessed by monitoring programs that rely on notifications of symptomatic illness. For monitoring of infectious diseases with a high proportion of asymptomatic cases or a low reporting rate, molecular sequence data combined with modern coalescent-based techniques offer ...
W. Marijn van Ballegooijen+5 more
openalex +4 more sources
Inference of Markovian Properties of Molecular Sequences from NGS Data and Applications to Comparative Genomics [PDF]
Abstract Motivation: Next-generation sequencing (NGS) technologies generate large amounts of short read data for many different organisms. The fact that NGS reads are generally short makes it challenging to assemble the reads and reconstruct the original genome sequence.
Jie Ren+5 more
openalex +6 more sources
Objective: To identify and validate circulating micro RNAs (miRNAs) that mark gene expression changes in articular cartilage early in osteoarthritis (OA) pathophysiology process.
Yolande F. M. Ramos+7 more
doaj +1 more source
Zoonotic Malaria Risk in Serra Do Mar, Atlantic Forest, Brazil
Here, the main goal is to assess natural infections of Plasmodium spp. in anophelines in a forest reserve from the same region where we previously found a surprisingly high rate (5.2%) of plasmodia infections (n = 25) in Kerteszia mosquitoes (N = 480) on
Marina E. O. Rangel+7 more
doaj +1 more source
Rise and Fall of SARS-CoV-2 Lineage A.27 in Germany
Here, we report on the increasing frequency of the SARS-CoV-2 lineage A.27 in Germany during the first months of 2021. Genomic surveillance identified 710 A.27 genomes in Germany as of 2 May 2021, with a vast majority identified in laboratories from a ...
Sébastien Calvignac-Spencer+10 more
doaj +1 more source
Molecular Acquisition, Cleaning and Evaluation in R (MACER) - A tool to assemble molecular marker datasets from BOLD and GenBank [PDF]
Molecular sequence data is an essential component for many biological fields of study. The strength of these data is in their ability to be centralised and compared across research studies.
Robert Young+3 more
doaj +3 more sources