The detection of linkage disequilibrium in molecular sequence data. [PDF]
Genetics, 1995 Abstract Studies of genetic variation in natural populations at the sequence level usually show that most polymorphic sites are very asymmetrical in allele frequencies, with the rarer allele at a site near fixation. When the rarer allele at a site is present only a few times in the sample, say below five representatives, it becomes very ...
Richard C Lewontin
openaire +4 more sources
Diversification of Neoaves: integration of molecular sequence data and fossils [PDF]
Biology Letters, 2006 Patterns of diversification and timing of evolution within Neoaves, which includes almost 95% of all bird species, are virtually unknown. On the other hand, molecular data consistently indicate a Cretaceous origin of many neoavian lineages and the fossil record seems to support an Early Tertiary diversification. Here, we present the first well-resolved
Gerald Mayr +10 more
openaire +4 more sources
Molecular Phylogenetics of Poaceae: An Expanded Analysis ofrbcL Sequence Data
Molecular Phylogenetics and Evolution, 1996 Phylogenetic analyses of rbcL sequence data from grasses are presented, extending the work of an earlier study. Based on molecular evidence that Joinvilleaceae and Restionaceae are closely allied to Poaceae, species from these families and from a distantly related dicot were variously employed as outgroups and analyzed with 23 species of Poaceae using ...
Melvin R. Duvall, Brian R. Morton
openaire +4 more sources
Population Subdivision and Molecular Sequence Variation: Theory and Analysis ofDrosophila ananassaeData [PDF]
Genetics, 2003 AbstractPopulation subdivision complicates analysis of molecular variation. Even if neutrality is assumed, three evolutionary forces need to be considered: migration, mutation, and drift. Simplification can be achieved by assuming that the process of migration among and drift within subpopulations is occurring fast compared to mutation and drift in the
Sujata Mohanty +5 more
openaire +4 more sources
Extracting Dwell Time Sequences from Processive Molecular Motor Data [PDF]
Biophysical Journal, 2006 Processive molecular motors, such as kinesin, myosin, or dynein, convert chemical energy into mechanical energy by hydrolyzing ATP. The mechanical energy is used for moving in discrete steps along the cytoskeleton and carrying a molecular load. Single-molecule recordings of motor position along a substrate polymer appear as a stochastic staircase ...
Lorin S. Milescu +3 more
openaire +5 more sources
Molecular BioComputing Suite: A Word Processor Add-In for the Analysis and Manipulation of Nucleic Acid and Protein Sequence Data [PDF]
BioTechniques, 2001 In all fields of molecular biology, researchers are increasingly challenged by experiments planned and evaluated on the basis of nucleic acid and protein sequence data generally retrieved from public databases.
Patrick Y. Muller +2 more
doaj +2 more sources
Molecular Sequence Data of Hepatitis B Virus and Genetic Diversity After Vaccination [PDF]
American Journal of Epidemiology, 2009 The effect of vaccination programs on transmission of infectious disease is usually assessed by monitoring programs that rely on notifications of symptomatic illness. For monitoring of infectious diseases with a high proportion of asymptomatic cases or a low reporting rate, molecular sequence data combined with modern coalescent-based techniques offer ...
van Ballegooijen, WMrivm +5 more
openaire +5 more sources
A Model Information Management Plan for Molecular Pathology Sequence Data Using Standards [PDF]
The Journal of Molecular Diagnostics, 2019 Incorporating genetic variant data into the electronic health record (EHR) in discrete computable fashion has vexed the informatics community for years. Genetic sequence test results are typically communicated by the molecular laboratory and stored in the EHR as textual documents. Although text documents are useful for human readability and initial use,
Walter S. Campbell +7 more
openaire +4 more sources
Impact of molecular sequence data completeness on HIV cluster detection and a network science approach to enhance detection. [PDF]
Sci Rep, 2022 Mazrouee S +8 more
europepmc +3 more sources
Molecular Acquisition, Cleaning and Evaluation in R (MACER) - A tool to assemble molecular marker datasets from BOLD and GenBank [PDF]
Biodiversity Data Journal, 2021 Molecular sequence data is an essential component for many biological fields of study. The strength of these data is in their ability to be centralised and compared across research studies.
Robert Young +3 more
doaj +3 more sources