Results 41 to 50 of about 28,841,045 (284)

The detection of linkage disequilibrium in molecular sequence data. [PDF]

open access: yesGenetics, 1995
Abstract Studies of genetic variation in natural populations at the sequence level usually show that most polymorphic sites are very asymmetrical in allele frequencies, with the rarer allele at a site near fixation. When the rarer allele at a site is present only a few times in the sample, say below five representatives, it becomes very ...
openaire   +2 more sources

An expressed sequence tag survey of gene expression in the pond snail Lymnaea stagnalis, an intermediate vector of Fasciola hepatica [PDF]

open access: yes, 2005
The pond snail Lymnaea stagnalis is an intermediate vector for the liver fluke Fasciola hepatica, a common parasite of ruminants and humans. Yet, despite being a disease of medical and economic importance, as well as a potentially useful comparative tool,
Davison, A., Blaxter, M. L.
core   +1 more source

AlphaFold Protein Structure Database for Sequence-Independent Molecular Replacement

open access: yesCrystals, 2021
Crystallographic phasing recovers the phase information that is lost during a diffraction experiment. Molecular replacement is a commonly used phasing method for crystal structures in the protein data bank.
Lawrence Chai   +7 more
doaj   +1 more source

Molecular phylogeny of brachiopods and phoronids based on nuclear-encoded small subunit ribosomal RNA gene sequences [PDF]

open access: yes, 1998
Brachiopod and phoronid phylogeny is inferred from SSU rDNA sequences of 28 articulate and nine inarticulate brachiopods, three phoronids, two ectoprocts and various outgroups, using gene trees reconstructed by weighted parsimony, distance and maximum ...
A. Gawthrop   +5 more
core   +1 more source

Reconstructing mammalian phylogenies : a detailed comparison of the cytochrome b and cytochrome oxidase subunit I mitochondrial genes [PDF]

open access: yes, 2010
The phylogeny and taxonomy of mammalian species were originally based upon shared or derived morphological characteristics. However, genetic analyses have more recently played an increasingly important role in confirming existing or establishing often ...
Adrian M. T. Linacre   +18 more
core   +4 more sources

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

Phylogeny of Kinorhyncha Based on Morphology and Two Molecular Loci. [PDF]

open access: yesPLoS ONE, 2015
The phylogeny of Kinorhyncha was analyzed using morphology and the molecular loci 18S rRNA and 28S rRNA. The different datasets were analyzed separately and in combination, using maximum likelihood and Bayesian Inference.
Martin V Sørensen   +6 more
doaj   +1 more source

Accurate Reconstruction of Molecular Phylogenies for Proteins Using Codon and Amino Acid Unified Sequence Alignments (CAUSA) [PDF]

open access: yes, 2011
Based on molecular clock hypothesis, and neutral theory of molecular evolution, molecular phylogenies have been widely used for inferring evolutionary history of organisms and individual genes.
Jingjie Hu   +7 more
core  

Southern-by-Sequencing: A Robust Screening Approach for Molecular Characterization of Genetically Modified Crops

open access: yesThe Plant Genome, 2015
Molecular characterization of events is an integral part of the advancement process during genetically modified (GM) crop product development. Assessment of these events is traditionally accomplished by polymerase chain reaction (PCR) and Southern blot ...
Gina M. Zastrow-Hayes   +9 more
doaj   +1 more source

Extracting Dwell Time Sequences from Processive Molecular Motor Data [PDF]

open access: yesBiophysical Journal, 2006
Processive molecular motors, such as kinesin, myosin, or dynein, convert chemical energy into mechanical energy by hydrolyzing ATP. The mechanical energy is used for moving in discrete steps along the cytoskeleton and carrying a molecular load. Single-molecule recordings of motor position along a substrate polymer appear as a stochastic staircase ...
Milescu, Lorin S.   +3 more
openaire   +2 more sources

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