Optimizing nucleic acid sequences for a molecular data recorder [PDF]
We recently reported the design for a DNA nano-device that can record and store molecular signals. Here we present an evolutionary algorithm tailored to optimising nucleic acid sequences that predictively fold into our desired target structures. In our approach, a DNA device is first specified abstractly: the topology of the individual strands and ...
Ben Shirt-Ediss+4 more
openaire +2 more sources
A preliminary molecular phylogeny of the family Hydroptilidae (Trichoptera): an exploration of combined targeted enrichment data and legacy sequence data [PDF]
Hydroptilidae is an extremely diverse family within Trichoptera, containing over 2,600 known species, that displays a wide array of ecological, morphological, and habitat diversity.
Robin E. Thomson+2 more
doaj +3 more sources
Molecular Epidemiology of O139 Vibrio cholerae: Mutation, Lateral Gene Transfer, and Founder Flush
Vibrio cholerae in O-group 139 was first isolated in 1992 and by 1993 had been found throughout the Indian subcontinent. This epidemic expansion probably resulted from a single source after a lateral gene transfer (LGT) event that changed the serotype of
Pallavi Garg+5 more
doaj +1 more source
Molecular Sequence Data of Hepatitis B Virus and Genetic Diversity After Vaccination [PDF]
The effect of vaccination programs on transmission of infectious disease is usually assessed by monitoring programs that rely on notifications of symptomatic illness. For monitoring of infectious diseases with a high proportion of asymptomatic cases or a low reporting rate, molecular sequence data combined with modern coalescent-based techniques offer ...
W. Marijn van Ballegooijen+5 more
openalex +5 more sources
A cross-sectional analysis of stored Ziehl-Neelsen (ZN)-stained sputum smear slides (SSS) obtained from two public tuberculosis referral laboratories located in Juiz de Fora, Minas Gerais, was carried out to distinguish Mycobacterium bovis from other ...
Marcio Roberto Silva+7 more
doaj +1 more source
Population Subdivision and Molecular Sequence Variation: Theory and Analysis ofDrosophila ananassaeData [PDF]
AbstractPopulation subdivision complicates analysis of molecular variation. Even if neutrality is assumed, three evolutionary forces need to be considered: migration, mutation, and drift. Simplification can be achieved by assuming that the process of migration among and drift within subpopulations is occurring fast compared to mutation and drift in the
Claus Vogl+4 more
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Foot-and-Mouth Disease Virus Serotype A in Egypt
We describe the characterization of a foot-and-mouth disease (FMD) serotype A virus responsible for recent outbreaks of disease in Egypt. Phylogenetic analysis of VP1 nucleotide sequences demonstrated a close relationship to recent FMD virus isolates ...
Nick J. Knowles+12 more
doaj +1 more source
The Barcode of Life Data Portal: bridging the biodiversity informatics divide for DNA barcoding. [PDF]
With the volume of molecular sequence data that is systematically being generated globally, there is a need for centralized resources for data exploration and analytics.
Indra Neil Sarkar, Michael Trizna
doaj +1 more source
Classification of molecular sequence data using Bayesian phylogenetic mixture models [PDF]
Rate variation among the sites of a molecular sequence is commonly found in applications of phylogenetic inference. Several approaches exist to account for this feature but they do not usually enable the investigator to pinpoint the sites that evolve under one or another rate of evolution in a straightforward manner.
Loza-Reyes, E.+2 more
openaire +3 more sources
Introducción. Los dos subgéneros en los cuales se divide el género Leishmania: Viannia y Leishmania, presentan diferencias significativas en las manifestaciones clínicas que causan, en su comportamiento de crecimiento en cultivos in vitro, en sus ...
Marcel Marín+4 more
doaj +1 more source