Molecular interaction networks in the analyses of sequence variation and proteomics data [PDF]
Protein–protein interaction networks are typically generated in standard cell lines or model organisms as it is prohibitively difficult to record large interaction datasets from specific tissues or disease models at a reasonable pace. Although the interaction data are of high confidence, they thus do not reflect in vivo relationships as such.
openaire +3 more sources
Homologous Pairing between Long DNA Double Helices
Molecular recognition between two double stranded (ds) DNA with homologous sequences may not seem compatible with the B-DNA structure because the sequence information is hidden when it is used for joining the two strands.
Mazur, Alexey K.
core +1 more source
The EM Algorithm and the Rise of Computational Biology [PDF]
In the past decade computational biology has grown from a cottage industry with a handful of researchers to an attractive interdisciplinary field, catching the attention and imagination of many quantitatively-minded scientists.
Citable Link +3 more
core +3 more sources
Phylogeny of Kinorhyncha Based on Morphology and Two Molecular Loci. [PDF]
The phylogeny of Kinorhyncha was analyzed using morphology and the molecular loci 18S rRNA and 28S rRNA. The different datasets were analyzed separately and in combination, using maximum likelihood and Bayesian Inference.
Martin V Sørensen +6 more
doaj +1 more source
Molecular characterization of events is an integral part of the advancement process during genetically modified (GM) crop product development. Assessment of these events is traditionally accomplished by polymerase chain reaction (PCR) and Southern blot ...
Gina M. Zastrow-Hayes +9 more
doaj +1 more source
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
Marine nematode taxonomy in the DNA age: the present and future of molecular tools to access their biodiversity [PDF]
Molecular taxonomy is one of the most promising yet challenging fields of biology. Molecular markers such as nuclear and mitochondrial genes are being used in a variety of studies surveying marine nematode taxa.
da Silva, Maria Cristina +7 more
core +2 more sources
RAD50 missense variants differentially affect the DNA damage response and mitotic progression
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker +9 more
wiley +1 more source
Lynds 1622: a nearby star forming cloud projected on Orion B?
We present results of optical spectroscopic and photometric observation of the pre-main sequence stars associated with the cometary shaped dark cloud Lynds 1622, and 12CO and 13CO observations of the cloud.
A. Gáspár +65 more
core +1 more source
FlatNJ: A novel network-based approach to visualize evolutionary and biogeographical relationships [PDF]
Split networks are a type of phylogenetic network that allow visualization of conflict in evolutionary data. We present a new method for constructing such networks called FlatNetJoining (FlatNJ).
Balvočiūtė, Monika +2 more
core +1 more source

