Results 71 to 80 of about 2,703,182 (313)

The extremal values of the Wiener index of a tree with given degree sequence [PDF]

, 2007
The Wiener index of a graph is the sum of the distances between all pairs of vertices, it has been one of the main descriptors that correlate achemical compound's molecular graph with experimentally gathered data regarding the compound's characteristics.
Wang, Hua
core   +3 more sources

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

FEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali, Gloria Giacomello, Michela Vuono, Silvia Gregori   +3 more
wiley   +1 more source

Natural variability of Kozak sequences correlates with function in a zebrafish model. [PDF]

PLoS ONE, 2014
In eukaryotes, targeting the small ribosomal subunit to the mRNA transcript requires a Kozak sequence at the translation initiation site. Despite the critical importance of the Kozak sequence to regulation of gene expression, there have been no ...
Steven J Grzegorski, Estelle F Chiari, Amy Robbins, Phillip E Kish, Alon Kahana   +4 more
doaj   +1 more source

Leishmania donovani populations in Eastern Sudan: temporal structuring and a link between human and canine transmission. [PDF]

, 2014
BACKGROUND: Visceral leishmaniasis (VL), caused by the members of the Leishmania donovani complex, has been responsible for devastating VL epidemics in the Sudan.
Baleela, Rania, Fitzpatrick, Sinead, Kuhls, Katrin, Llewellyn, Martin S, Mauricio, Isabel L, Miles, Michael A, Schönian, Gabriele   +6 more
core   +3 more sources

FoxO1 signaling in B cell malignancies and its therapeutic targeting

FEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac, Petra Pavelkova, Laura Ondrisova, Marek Mraz   +3 more
wiley   +1 more source

Marine nematode taxonomy in the DNA age: the present and future of molecular tools to access their biodiversity [PDF]

, 2010
Molecular taxonomy is one of the most promising yet challenging fields of biology. Molecular markers such as nuclear and mitochondrial genes are being used in a variety of studies surveying marine nematode taxa.
da Silva, Maria Cristina, de Ley, Paul, Decraemer, Wilfrida, dos santos correla, Maria Tereza, Esteves, Andre Morgado, Gomes Fonseca Genevois, Veronica, Rieger, Tania Tassinari, Rodriguez Da Silva, Neyvan Renato   +7 more
core   +3 more sources

Reliability and Utility of Standard Gene Sequence Barcodes for the Identification and Differentiation of Cyst Nematodes of the Genus Heterodera

Journal of Nematology, 2022
Difficulties inherent in the morphological identification of cyst nematodes of the genus Heterodera Schmidt, 1871, an important lineage of plant parasites, has led to broad adoption of molecular methods for diagnosing and differentiating species.
Huston Daniel C., Khudhir Manda, Hodda Mike   +2 more
doaj   +1 more source

FAST: FAST Analysis of Sequences Toolbox. [PDF]

, 2015
FAST (FAST Analysis of Sequences Toolbox) provides simple, powerful open source command-line tools to filter, transform, annotate and analyze biological sequence data. Modeled after the GNU (GNU's Not Unix) Textutils such as grep, cut, and tr, FAST tools
Claudia J. Canales, Dana L. Carper, David H. Ardell, David H. Ardell, Katherine C.H. Amrine, Katherine C.H. Amrine, Kyle T. Kauffman, Peter J. Becich, Raymond S. Lee, Travis J. Lawrence   +9 more
core   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

FEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi, WanTing Kong, Camille Blériot, Joel T. Haas   +3 more
wiley   +1 more source

Analysis of recombination in molecular sequence data

, 2008
Wir präsentieren Recco, eine neue und schnelle Methode zur Analyse von Rekombinationen in multiplen Alignments. Recco basiert auf einem dynamischen Programm, welches eine Sequenz im Alignment durch die anderen Sequenzen im Alignment rekonstruiert, wobei die Operatoren Mutation und Rekombination erlaubt sind.
openaire   +3 more sources