Results 11 to 20 of about 19,367,956 (387)
The Infra-Red Spectrum and Molecular Structure of HNCS [PDF]
, 1950 From an examination of the microwave spectra of four isotopic species of isothiocyanic acid, Beard and Dailey (1) recently obtained the following values for the molecular parameters in the ground vibrational ...
Llewellyn H. Jones, Richard M. Badger
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Structure and dynamics of the E. coli chemotaxis core signaling complex by cryo-electron tomography and molecular simulations [PDF]
, 2020 To enable the processing of chemical gradients, chemotactic bacteria possess large arrays of transmembrane chemoreceptors, the histidine kinase CheA, and the adaptor protein CheW, organized as coupled core-signaling units (CSU). Despite decades of study,
Cassidy, Keith +8 more
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Benchmarking tomographic acquisition schemes for high-resolution structural biology
Nature Communications, 2020 Here the authors systematically benchmark cryo-electron tomography acquisition schemes to optimize the attainable resolution for subtomogram averaging, and find that dose-symmetric acquisition with even angular sampling provides a better outcome than ...
Beata Turoňová +7 more
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Structure of the human marker of self 5-transmembrane receptor CD47
Nature Communications, 2021 CD47 is a transmembrane receptor involved in the regulation of various signalling pathways and a promising target for immuno-oncology therapeutics. Here, the authors present the crystal structure of full-length human CD47 and provide insights into the ...
Gustavo Fenalti +15 more
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Molecular structure of a prevalent amyloid-β fibril polymorph from Alzheimer's disease brain tissue
Proceedings of the National Academy of Sciences of the United States of America, 2020 Significance Amyloid-β (Aβ) fibrils are the main component of amyloid plaques that develop in brain tissue of Alzheimer’s disease (AD) patients. Aβ fibrils have a variety of molecular structures called polymorphs.
U. Ghosh +3 more
semanticscholar +1 more source
On the emergence of molecular structure [PDF]
Physical Review A, 2011 The structure of {a(+/-),a(+/-),b(+/-)}-type Coulombic systems is characterized by the effective ground-state density of the a-type particles, computed via nonrelativistic quantum mechanics without introduction of the Born-Oppenheimer approximation. A structural transition is observed when varying the relative mass of the a- and b-type particles, e.g.,
Matyus, E +3 more
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Adipocyte HIF2α functions as a thermostat via PKA Cα regulation in beige adipocytes
Nature Communications, 2022 Thermogenic adipocytes maintain body temperature in response to cold, but how this is tuned during cold and re-warming is unclear. Here, the authors show HIF2α inhibits beige adipocyte retention, regulating PKA catalysis to control dynamic adipocyte ...
Ji Seul Han +14 more
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A Molecular–Structure Hypothesis [PDF]
International Journal of Molecular Sciences, 2010 The self-similar symmetry that occurs between atomic nuclei, biological growth structures, the solar system, globular clusters and spiral galaxies suggests that a similar pattern should characterize atomic and molecular structures. This possibility is explored in terms of the current molecular structure-hypothesis and its extension into four ...
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Structure of human TRPM8 channel
Communications Biology, 2023 TRPM8 is a non-selective cation channel permeable to both monovalent and divalent cations that is activated by multiple factors, such as temperature, voltage, pressure, and changes in osmolality. It is a therapeutic target for anticancer drug development,
Sergii Palchevskyi +7 more
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Multiplex flow magnetic tweezers reveal rare enzymatic events with single molecule precision
Nature Communications, 2020 Single molecule force measurements have shed light on dynamic biological events, but rare events escape notice owing to low throughput of the methods. Here, the authors combine an array of magnetic tweezers with lateral flow to increase throughput 100 ...
Rohit Agarwal, Karl E. Duderstadt
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