Soy Protein: Molecular Structure Revisited and Recent Advances in Processing Technologies.
Annual Review of Food Science and Technology, 2020 Rising health concerns and increasing obesity levels in human society have led some consumers to cut back on animal protein consumption and switch to plant-based proteins as an alternative.
Xiaonan Sui +2 more
semanticscholar +1 more source
Structure of the human marker of self 5-transmembrane receptor CD47
Nature Communications, 2021 CD47 is a transmembrane receptor involved in the regulation of various signalling pathways and a promising target for immuno-oncology therapeutics. Here, the authors present the crystal structure of full-length human CD47 and provide insights into the ...
Gustavo Fenalti +15 more
doaj +1 more source
Molecular structure of a prevalent amyloid-β fibril polymorph from Alzheimer's disease brain tissue
Proceedings of the National Academy of Sciences of the United States of America, 2020 Significance Amyloid-β (Aβ) fibrils are the main component of amyloid plaques that develop in brain tissue of Alzheimer’s disease (AD) patients. Aβ fibrils have a variety of molecular structures called polymorphs.
U. Ghosh +3 more
semanticscholar +1 more source
Adipocyte HIF2α functions as a thermostat via PKA Cα regulation in beige adipocytes
Nature Communications, 2022 Thermogenic adipocytes maintain body temperature in response to cold, but how this is tuned during cold and re-warming is unclear. Here, the authors show HIF2α inhibits beige adipocyte retention, regulating PKA catalysis to control dynamic adipocyte ...
Ji Seul Han +14 more
doaj +1 more source
The Description of Molecular Structure [PDF]
Proceedings of the National Academy of Sciences, 1975 With the kind permission of the chair, I dedicate this lecture to the memory of my father, Leland W. Parr, who died in December of 1973. For many years Dr. Parr was Professor of Bacteriology and Public Health at George Washington University Medical School, here in Washington.
openaire +2 more sources
Molecular ferroelectric contributions to anomalous hysteresis in hybrid perovskite solar cells [PDF]
, 2014 We report a model describing the molecular orientation disorder in CH3NH3PbI3, solving a classical Hamiltonian parametrised with electronic structure calculations, with the nature of the motions informed by ab-initio molecular dynamics.
Anderson P. W. +4 more
core +3 more sources
Structure of human TRPM8 channel
Communications Biology, 2023 TRPM8 is a non-selective cation channel permeable to both monovalent and divalent cations that is activated by multiple factors, such as temperature, voltage, pressure, and changes in osmolality. It is a therapeutic target for anticancer drug development,
Sergii Palchevskyi +7 more
doaj +1 more source
Multiplex flow magnetic tweezers reveal rare enzymatic events with single molecule precision
Nature Communications, 2020 Single molecule force measurements have shed light on dynamic biological events, but rare events escape notice owing to low throughput of the methods. Here, the authors combine an array of magnetic tweezers with lateral flow to increase throughput 100 ...
Rohit Agarwal, Karl E. Duderstadt
doaj +1 more source
Characterisation of HOIP RBR E3 ligase conformational dynamics using integrative modelling
Scientific Reports, 2022 Multidomain proteins composed of individual domains connected by flexible linkers pose a challenge for structural studies due to their intrinsic conformational dynamics.
Marius Kausas +3 more
doaj +1 more source
The simulation of molecular clouds formation in the Milky Way [PDF]
, 2012 Using 3D hydrodynamic calculations we simulate formation of molecular clouds in the Galaxy. The simulations take into account molecular hydrogen chemical kinetics, cooling and heating processes.
A. M. Sobolev +88 more
core +1 more source