Results 21 to 30 of about 19,935,117 (378)

GLP-1 receptor agonism ameliorates hepatic VLDL overproduction and de novo lipogenesis in insulin resistance

open access: yesMolecular Metabolism, 2014
Background/objectives: Fasting dyslipidemia is commonly observed in insulin resistant states and mechanistically linked to hepatic overproduction of very low density lipoprotein (VLDL).
Jennifer Taher   +9 more
doaj   +1 more source

Comparison of substrate specificity of the ubiquitin ligases Nedd4 and Nedd4‐2 using proteome arrays

open access: yesMolecular Systems Biology, 2009
Target recognition by the ubiquitin system is mediated by E3 ubiquitin ligases. Nedd4 family members are E3 ligases comprised of a C2 domain, 2–4 WW domains that bind PY motifs (L/PPxY) and a ubiquitin ligase HECT domain.
Avinash Persaud   +8 more
doaj   +1 more source

Potassium trihydrogen dioxalate dihydrate (KTO) nonlinear optical (NLO) single crystal for optical limiting application

open access: yesResults in Physics, 2023
In nonlinear optics, optical power limiting (OPL) compounds are known to be an important class of materials because it has the ability to protect the optical sensor components as well as human eyes from the abrupt intense laser power. Here, we have grown
Ramki Chakaravarthy   +5 more
doaj   +1 more source

Supersonic turbulence and structure of interstellar molecular clouds [PDF]

open access: yes, 2002
The interstellar medium (ISM) provides a unique laboratory for highly supersonic, driven hydrodynamics turbulence. We present a theory of such turbulence, confirm it by numerical simulations, and use the results to explain observational properties of ...
B. Dubrulle   +28 more
core   +2 more sources

Fine- and hyperfine-structure effects in molecular photoionization: II. Resonance-enhanced multiphoton ionization and hyperfine-selective generation of molecular cations [PDF]

open access: yes, 2016
Resonance-enhanced multiphoton ionization (REMPI) is a widely used technique for studying molecular photoionization and producing molecular cations for spectroscopy and dynamics studies. Here, we present a model for describing hyperfine-structure effects
Germann, Matthias, Willitsch, Stefan
core   +2 more sources

Metabolic reconstruction identifies strain‐specific regulation of virulence in Toxoplasma gondii

open access: yesMolecular Systems Biology, 2013
Increasingly, metabolic potential is proving to be a critical determinant governing a pathogen's virulence as well as its capacity to expand its host range. To understand the potential contribution of metabolism to strain‐specific infectivity differences,
Carl Song   +6 more
doaj   +1 more source

Adsorption of Methyl Orange on Bentonite: Design, Modeling, and Analysis of Experiments [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering, 2023
The study examines the possibility of removing Methyl Orange (MO) from aqueous solutions using crude bentonite. SEM-EDX (scanning electron microscopy) and XRD (X-Ray Diffraction) analyses were performed to characterize the material.
Fatiha Bessaha   +3 more
doaj   +1 more source

Interplay of buried histidine protonation and protein stability in prion misfolding

open access: yesScientific Reports, 2017
Misofolding of mammalian prion proteins (PrP) is believed to be the cause of a group of rare and fatal neurodegenerative diseases. Despite intense scrutiny however, the mechanism of the misfolding reaction remains unclear.
Anatoly Malevanets   +10 more
doaj   +1 more source

Structure of a Ty1 restriction factor reveals the molecular basis of transposition copy number control

open access: yesNature Communications, 2021
In Saccharomyces cerevisiae, unchecked proliferation of Ty1 retrotransposons is controlled by the process of copy number control (CNC), which requires the p22/p18 protein, translated from an internal transcript within the Ty1 GAG gene.
Matthew A. Cottee   +7 more
doaj   +1 more source

Acid Red 114 Removal Using a Low-Cost Material: Experimental Study and Statistical Physics Modeling [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering
An eco-friendly and cost-effective biosorbent has been developed for the efficient elimination of acid red 114 dye from aqueous media. Batch studies were carried out to determine the effects of various operating parameters, namely the effect of ...
Fatiha Bessaha   +6 more
doaj   +1 more source

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