Results 21 to 30 of about 19,554,159 (311)
Characterisation of HOIP RBR E3 ligase conformational dynamics using integrative modelling
Scientific Reports, 2022 Multidomain proteins composed of individual domains connected by flexible linkers pose a challenge for structural studies due to their intrinsic conformational dynamics.
Marius Kausas +3 more
doaj +1 more source
Molecular Metabolism, 2014 Background/objectives: Fasting dyslipidemia is commonly observed in insulin resistant states and mechanistically linked to hepatic overproduction of very low density lipoprotein (VLDL).
Jennifer Taher +9 more
doaj +1 more source
Molecular Structure and Energy [PDF]
Nature, 1921 IN some recent communications on the structure of molecules based on the Lewis-Langmuir theory the question of the energy of molecules seems to have been left out of account. The models for halogen molecules proposed by Prof. A. O. Rankine (Proc. Roy.
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Comparison of substrate specificity of the ubiquitin ligases Nedd4 and Nedd4‐2 using proteome arrays
Molecular Systems Biology, 2009 Target recognition by the ubiquitin system is mediated by E3 ubiquitin ligases. Nedd4 family members are E3 ligases comprised of a C2 domain, 2–4 WW domains that bind PY motifs (L/PPxY) and a ubiquitin ligase HECT domain.
Avinash Persaud +8 more
doaj +1 more source
Mesomorphism, molecular structure and dynamics of polydiethylsiloxane [PDF]
, 1990 The correlation between the phase behaviour of polydiethylsiloxane (PDES) and conformational and motional changes at the various disordering transitions has been investigated by nuclear magnetic resonance (n.m.r.), dielectric relaxation and shear ...
Kögler, Gerhard +2 more
core +2 more sources
Metabolic reconstruction identifies strain‐specific regulation of virulence in Toxoplasma gondii
Molecular Systems Biology, 2013 Increasingly, metabolic potential is proving to be a critical determinant governing a pathogen's virulence as well as its capacity to expand its host range. To understand the potential contribution of metabolism to strain‐specific infectivity differences,
Carl Song +6 more
doaj +1 more source
Nature Communications, 2021 In Saccharomyces cerevisiae, unchecked proliferation of Ty1 retrotransposons is controlled by the process of copy number control (CNC), which requires the p22/p18 protein, translated from an internal transcript within the Ty1 GAG gene.
Matthew A. Cottee +7 more
doaj +1 more source
Fine- and hyperfine-structure effects in molecular photoionization: II. Resonance-enhanced multiphoton ionization and hyperfine-selective generation of molecular cations [PDF]
, 2016 Resonance-enhanced multiphoton ionization (REMPI) is a widely used technique for studying molecular photoionization and producing molecular cations for spectroscopy and dynamics studies. Here, we present a model for describing hyperfine-structure effects
Germann, Matthias, Willitsch, Stefan
core +2 more sources
Skeletal muscle: A review of molecular structure and function, in health and disease
Wiley Interdisciplinary Reviews: Systems Biology and Medicine, 2019 Decades of research in skeletal muscle physiology have provided multiscale insights into the structural and functional complexity of this important anatomical tissue, designed to accomplish the task of generating contraction, force and movement. Skeletal
Kavitha Mukund, S. Subramaniam
semanticscholar +1 more source
Interplay of buried histidine protonation and protein stability in prion misfolding
Scientific Reports, 2017 Misofolding of mammalian prion proteins (PrP) is believed to be the cause of a group of rare and fatal neurodegenerative diseases. Despite intense scrutiny however, the mechanism of the misfolding reaction remains unclear.
Anatoly Malevanets +10 more
doaj +1 more source