Results 41 to 50 of about 19,554,258 (410)
The WD40 domain of the SCFCdc4ubiquitin ligase targets substrates via multiple phosphorylated degron motifs. The authors define a second degron-binding WD40 pocket that imparts a negative allosteric effect on binding to the primary pocket, and thereby ...
Veronika Csizmok+11 more
doaj +1 more source
FAN1 is a structure-selective DNA repair nuclease with 5′ flap endonuclease activity, involved in the repair of interstrand DNA crosslinks. It is the only eukaryotic protein with a virus-type replication-repair nuclease (“VRR-Nuc”) “module” that commonly
Simon Pennell+9 more
doaj +1 more source
Molecular Property Prediction Based on Graph Structure Learning [PDF]
Molecular property prediction (MPP) is a fundamental but challenging task in the computer-aided drug discovery process. More and more recent works employ different graph-based models for MPP, which have made considerable progress in improving prediction performance.
arxiv
Supersonic turbulence and structure of interstellar molecular clouds [PDF]
The interstellar medium (ISM) provides a unique laboratory for highly supersonic, driven hydrodynamics turbulence. We present a theory of such turbulence, confirm it by numerical simulations, and use the results to explain observational properties of ...
B. Dubrulle+28 more
core +2 more sources
Dynamic molecular structure of plant biomass-derived black carbon (biochar).
Char black carbon (BC), the solid residue of incomplete combustion, is continuously being added to soils and sediments due to natural vegetation fires, anthropogenic pollution, and new strategies for carbon sequestration ("biochar").
M. Keiluweit+3 more
semanticscholar +1 more source
Friction and Molecular Structure [PDF]
I SHALL feel obliged if you will kindly allow me to ask any reader of NATURE whether moderate friction can so change the molecular structure of glass as to account for the following fact:— Last night, about twenty minutes after a paraffine lamp had been lighted and had been burning steadily, its glass chimney suddenly burst into small fragments at the ...
openaire +6 more sources
Biochars at the molecular level. Part 1 -- Insights into the molecular structures within biochars [PDF]
Biochars are black carbonaceous solids produced through biomass pyrolysis under conditions of little or no oxygen. Whilst their properties are well studied, and their applications numerous, the underlying molecular structures within biochars still need to be defined.
arxiv +1 more source
Molecular structures in charmonium spectrum: The $XYZ$ puzzle [PDF]
We study in the framework of a constituent quark model the possible contributions of molecular structures to the XYZ charmonium like states. We analyze simultaneously the $c\bar{c}$ structures and the possible molecular components in a formalism which allows us to treat channels below and above thresholds. The only molecular state found in the $1^{++}$
arxiv +1 more source
Rotational structure of weakly bound molecular ions
Relying on the quantization rule of Raab and Friedrich [Phys. Rev. A (2009) in press], we derive simple and accurate formulae for the number of rotational states supported by a weakly bound vibrational level of a diatomic molecular ion.
Friedrich, Bretislav, Lemeshko, Mikhail
core +1 more source
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali+3 more
wiley +1 more source