Results 91 to 100 of about 969,782 (213)

Efficacy of various extent of resection on survival rates of patients with pilocytic astrocytoma: based on a large population

Scientific Reports
Pilocytic astrocytoma (PA) is classified as a Grade I benign neuroglial tumor. The extent of surgical resection is a critical factor influencing the prognosis for patients with PA.
Jun Su, Shanshan Guo, Zheyuan Chen, Yiming Han, Jingwang Yan, Qiyun Tang, Yu Mao, Haiqiang Zhang, Guojiang Hou, Gaopan Dong, Chao Guo, Pengfei Yang   +11 more
doaj   +1 more source

Pemigatinib combined with immunotherapy and stereotactic body radiation therapy for FGFR2 fusion-positive advanced intrahepatic cholangiocarcinoma with brain metastasis: a Case Report

Frontiers in Pharmacology
BackgroundFGFR2 fusions or rearrangements occur in 13%–20% of patients with intrahepatic cholangiocarcinoma (iCCA). Pemigatinib, a representative FGFR inhibitor, is commonly used for targeted therapy in such patients.
Jiamin Guo, Lingqi Sun, Ye Chen, Ji Ma
doaj   +1 more source

Targeted Molecular Therapy in Glioblastoma

Journal of Oncology, 2020
Festuccia, Claudio, Biordi, Assunta Leda, Tombolini, Vincenzo, Hara, Akira, Bailey, David   +4 more
openaire   +2 more sources

Sarcoma: Molecular-Targeted Therapies

Annals of Oncology, 2012
ABSTRACT Sarcomas are rare heterogeneous malignant neoplasms that arise from mesenchymal tissues and are clinically divided into two main categories, that is, bone and soft tissue sarcomas. The overall frequency of sarcomas is ∼1% of all adult solid malignancies, and the incidence of bone sarcomas and soft-tissue sarcomas is estimated to be four ...
openaire   +1 more source

Molecular targeted therapies in metastatic melanoma

Pharmacogenomics and Personalized Medicine, 2013
The advent of personalized medicine has ushered in a new era for cancer therapy with a significant impact on the management of advanced melanoma. Molecular targeted therapies have shown promise in the management of various malignancies, including melanoma, with lower toxicity profiles and better overall survival as compared with conventional therapy ...
Chakraborty, Rima, Wieland, Carilyn N, Comfere, Nneka I   +2 more
openaire   +3 more sources

Higher cerebellum florbetapir uptake in cerebral amyloid angiopathy compared to Alzheimer's disease: A dual florbetapir and FDG PET study

Journal of Alzheimer's Disease Reports
Background Amyloid-β (Aβ) is the primary amyloidogenic protein involved in various diseases associated with cognitive dysfunction, including Alzheimer's disease (AD) and cerebral amyloid angiopathy (CAA).
Yuhui Sha, Chenhao Jia, Menglin Liang, Juanjuan Wu, Tianhao Zhang, Yicheng Zhu, Jing Yuan, Qijun Li, Zhaoxia Huang, Ruixue Cui, Jun Ni   +10 more
doaj   +1 more source

Molecular Targeted Therapy

Siriraj Medical Journal, 2006
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openaire   +1 more source

Effect of immune checkpoint inhibitor time-of-day infusion on survival in advanced biliary tract cancer: a propensity score-matched analysis

Frontiers in Immunology
BackgroundCircadian rhythms in the immune system and anti-tumor responses are underexplored in cancer immunotherapy. Despite the success of immune checkpoint inhibitors (ICIs) in treating advanced biliary tract cancers (BTCs), not all patients benefit ...
Yichen Zheng, Fanfan Shi, Lingqi Sun, Jiamin Guo, Tonghui Ren, Ji Ma   +5 more
doaj   +1 more source

Transcription factor 19‐mediated epigenetic regulation of FOXM1/AURKB axis contributes to proliferation in clear cell renal carcinoma cells

MedComm, 2023
Yakun Luo, Qing Shi, Lu Wang, Shuijie Li, Wanhai Xu   +4 more
doaj   +1 more source

Novel Strategies to Optimize Targeted Molecular Imaging and Therapy [PDF]

, 2013
Improving patients’ clinical outcomes requires many levels of examination, owing to the enormous complexities of human disease and healthcare delivery. Our understanding of disease also requires many different levels of observation.
Norenberg, J.P. (Jeffrey)
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