Results 241 to 250 of about 6,883,814 (290)

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Immuno-Molecular Targeted Therapy Use and Survival Benefit in Patients with Stage IVB Cervical Carcinoma in Commission on Cancer^®-Accredited Facilities in the United States. [PDF]

Cancers (Basel)
Sitler CA, Tian C, Hamilton CA, Richardson MT, Chan JK, Kapp DS, Leath CA, Casablanca Y, Washington C, Chappell NP, Klopp AH, Shriver CD, Tarney CM, Bateman NW, Conrads TP, Maxwell GL, Phippen NT, Darcy KM.   +17 more
europepmc   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

[Advances of Molecular Targeted Therapy in EGFR-mutated Squamous Cell Lung Cancer]. [PDF]

Zhongguo Fei Ai Za Zhi
Xiong B, Ke W, Jiang W.
europepmc   +1 more source

Marrow-ablative consolidation chemotherapy and molecular targeted therapy delivered in a risk-adapted manner for newly diagnosed children with choroid plexus carcinoma: A work in progress. [PDF]

Neurooncol Adv
Yankelevich M, Zaky W, Lafay-Cousin L, Osorio D, Adamski J, Kordes U, Finlay JL, Prados M, Mueller S.   +8 more
europepmc   +1 more source

New strategy for monitoring targeted therapy: molecular imaging

International Journal of Nanomedicine, 2013
Fei-Fei Teng, Xue Meng, Xin-Dong Sun, Jin-Ming YuDepartment of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong University, Jinan, People's Republic of ChinaAbstract: Targeted therapy is becoming an increasingly important ...
Jinming Yu, Xue Meng, Feifei Teng
exaly   +1 more source

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Molecular targets in cancer therapy

Expert Review of Anticancer Therapy, 2013
24th EORTC-NCI-AACR Symposium on 'Molecular Targets and Cancer Therapeutics' 6-9 November 2012, Dublin, Ireland The EORTC-NCI-AACR Symposium is an annual meeting, jointly hosted by the European Organization for Research and Treatment of Cancer, the US National Cancer Institute and the American Association for Cancer Research, to encourage exchange of ...
Shivaani, Kummar, James H, Doroshow
openaire   +2 more sources

Molecular targets of gene therapy

The Annals of Thoracic Surgery, 1999
Ischemic reperfused heart represents a potential target for gene therapy because gene transfer can represent an alternate pharmacological approach to protect the heart from cellular injury. Gene therapy may be particularly useful to deal with previously unapproachable problems.
D K, Das, R M, Engelman, N, Maulik, J A, Rousou, J E, Flack, D W, Deaton   +5 more
openaire   +2 more sources

Molecular Targeting of Lymphatics for Therapy

Current Pharmaceutical Design, 2004
The dysfunction or proliferation of lymphatic vessels (lymphangiogenesis) is linked to a number of pathological conditions including lymphedema and cancer. The recent discovery and characterisation of the lymphangiogenic growth factors vascular endothelial growth factor-C (VEGF-C) and VEGF-D and of their receptor on lymphatic endothelial cells, VEGFR-3,
S A, Stacker, R A, Hughes, M G, Achen
openaire   +2 more sources

Molecular Targets for Papillomavirus Therapy

Current Drug Target -Infectious Disorders, 2003
Papillomaviruses are infectious agents for human and animal epithelial tissue, and nearly 100 distinct human types (HPVs) have been identified. When these viruses infect cutaneous or mucosal skin they can initially cause clinical warts or persistent infection with little or no visible manifestations.
V G, Wilson, G, Rosas-Acosta
openaire   +2 more sources