Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Recent advances in molecular targeted therapy of lung cancer: Possible application in translation medicine. [PDF]
Iran J Basic Med SciSalmani-Javan E +2 more
europepmc +1 more source
Toward Molecularly Targeted Therapies for Renal Disease
, 2017 Edward Grimley
openalex +1 more source
POS0032 Effectiveness of Switching from IL-6 Inhibitors to Other Targeted Molecular Therapies
Tadashi Okano +11 more
openalex +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Philadelphia Chromosome as a Clinically Favorable Prognostic Factor of B-cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma in Transplant-Ineligible Elderly Patients in the Era of Molecular-Targeted Therapy. [PDF]
CureusSaburi M +11 more
europepmc +1 more source
3. Up-to-date on the Pathogenesis of Inflammatory Bowel Disease and Molecular Targeted Therapy
Tadakazu Hisamatsu
openalex +2 more sources
Targeted Sequencing in Gastric Cancer: Association with Tumor Molecular Characteristics and FLOT Therapy Effectiveness [PDF]
Л. В. Спирина +8 more
openalex +1 more source
Inflammatory bowel diseases emerging therapies and promising molecular targets [PDF]
, 2012 Peter Mannon
openalex +1 more source