Results 61 to 70 of about 2,123,606 (402)

Alter between gut bacteria and blood metabolites and the anti-tumor effects of Faecalibacterium prausnitzii in breast cancer

BMC Microbiology, 2020
Background The aim was to evaluate the changes of 16S rDNA sequencing and LC-MS metabolomics in breast cancer and explore the growth inhibition of breast cancer cells by Faecalibacterium prausnitzii.
Ji Ma, Lingqi Sun, Ying Liu, Hui Ren, Yali Shen, Feng Bi, Tao Zhang, Xin Wang   +7 more
doaj   +1 more source

The value of 18F-FDG PET/CT in the systemic evaluation of patients with Rosai–Dorfman disease: a retrospective study and literature review

Orphanet Journal of Rare Diseases, 2023
Background Rosai–Dorfman disease (RDD) is a rare form of non-Langerhans cell histiocytic disease. The aim of this study was to review the characteristics of RDD using 18F-FDG PET/CT and determine its efficacy in the disease management. Results A total of
Xinyu Lu, Rongxi Wang, Zhaohui Zhu
doaj   +1 more source

A prognostic model for cervical cancer based on ferroptosis-related genes

Frontiers in Endocrinology, 2022
BackgroundFerroptosis is widely involved in the occurrence and development of various cancers, but a specific mechanism involving ferroptosis in cervical cancer is still unclear.MethodsBased on the expressions of ferroptosis-related genes, a prognostic ...
Huijun Du, Huijun Du, Yumei Tang, Yumei Tang, Xiaoying Ren, Xiaoying Ren, Fan Zhang, Fan Zhang, Wei Yang, Wei Yang, Le Cheng, Yunan Gao, Yunan Gao   +12 more
doaj   +1 more source

Molecular Targeted Therapy in the Treatment of Chordoma: A Systematic Review

Frontiers in Oncology, 2019
Objectives: Chordoma is a rare bone malignancy that affects the spine and skull base. Treatment dilemma leads to a high rate of local relapse and distant metastases. Molecular targeted therapy (MTT) is an option for advanced chordoma, but its therapeutic
T. Meng, Jiali Jin, Cong Jiang, Runzhi Huang, Huabin Yin, D. Song, Liming Cheng   +6 more
semanticscholar   +1 more source

Apoptosis and Molecular Targeting Therapy in Cancer [PDF]

BioMed Research International, 2014
Apoptosis is the programmed cell death which maintains the healthy survival/death balance in metazoan cells. Defect in apoptosis can cause cancer or autoimmunity, while enhanced apoptosis may cause degenerative diseases. The apoptotic signals contribute into safeguarding the genomic integrity while defective apoptosis may promote carcinogenesis.
Yusuke Ohba, Hidemichi Watari, Ali H. Abu-Almaaty, Noriaki Sakuragi, Mohamed K. Hassan   +4 more
openaire   +3 more sources

Quantitative assessment of renal functions using 68Ga-EDTA dynamic PET imaging in renal injury in mice of different origins

Frontiers in Medicine, 2023
BackgroundEarly detection of kidney diseases can be challenging as conventional methods such as blood tests or imaging techniques (computed tomography (CT), magnetic resonance imaging (MRI), or ultrasonography) may be insufficient to assess renal ...
Ying Ding, Ying Ding, Ying Ding, Yu Liu, Yu Liu, Yu Liu, Li Zhang, Li Zhang, Li Zhang, Yinqian Deng, Yinqian Deng, Yinqian Deng, Huanyu Chen, Huanyu Chen, Huanyu Chen, Xiaoli Lan, Xiaoli Lan, Xiaoli Lan, Dawei Jiang, Dawei Jiang, Dawei Jiang, Wei Cao, Wei Cao, Wei Cao   +23 more
doaj   +1 more source

Molecular classification and molecular targeted therapy of cancer [PDF]

Frontiers of Medicine, 2013
Various molecular analytical techniques have providedmore and more information which is necessary for theaccurate classification of diseases. Such informationhas enabled researchers to shift from morphology-based classification to molecular characteristics-basedclassification, also known as molecular classification.Molecular classifications of diseases can ...
Miao Xu, Yi Xin Zeng, Jianyong Shao
openaire   +3 more sources

Simulating the Evolution of Signaling Signatures during CART-Cell -- Tumor Cell Interactions [PDF]

arXiv, 2023
Immunotherapies have been proven to have significant therapeutic efficacy in the treatment of cancer. The last decade has seen adoptive cell therapies, such as chimeric antigen receptor T-cell (CART-cell) therapy, gain FDA approval against specific cancers.
arxiv  

Deep learning model for automatic image quality assessment in PET

BMC Medical Imaging, 2023
Background A variety of external factors might seriously degrade PET image quality and lead to inconsistent results. The aim of this study is to explore a potential PET image quality assessment (QA) method with deep learning (DL).
Haiqiong Zhang, Yu Liu, Yanmei Wang, Yanru Ma, Na Niu, Hongli Jing, Li Huo   +6 more
doaj   +1 more source

Perspective of molecular imaging and peptide receptor radionuclide therapy in pancreatic neuroendocrine tumors: where do we stand?

Journal of Pancreatology, 2023
The clinical use of nuclear medicine imaging and therapy in pancreatic neuroendocrine tumors has been greatly strengthened since the approval of 68Ga-DOTATATE and 177Lu-DOTATATE. However, many aspects are still under discussion.
Wenjia Zhu, Meixi Liu, Li Huo
doaj   +1 more source