Results 51 to 60 of about 6,883,814 (290)
Deep learning model for automatic image quality assessment in PET
BMC Medical Imaging, 2023 Background A variety of external factors might seriously degrade PET image quality and lead to inconsistent results. The aim of this study is to explore a potential PET image quality assessment (QA) method with deep learning (DL).
Haiqiong Zhang +6 more
doaj +1 more source
A prognostic model for cervical cancer based on ferroptosis-related genes
Frontiers in Endocrinology, 2022 BackgroundFerroptosis is widely involved in the occurrence and development of various cancers, but a specific mechanism involving ferroptosis in cervical cancer is still unclear.MethodsBased on the expressions of ferroptosis-related genes, a prognostic ...
Huijun Du +12 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Adult survivors of childhood acute lymphoblastic leukemia (ALL) are at risk of reduced exercise capacity, decreased physical activity levels, persistent fatigue, and neurocognitive deficits. The aim was to investigate exercise capacity and physical activity levels of adult survivors of childhood ALL and their associations with ...
Laura Jess +5 more
wiley +1 more source
Towards the optimization of tumor targeting radiolabeled peptides for molecular imaging and therapy [PDF]
, 2014 Radiopharmaceuticals based on regulatory peptides have become an indispensable tool in nuclear medicine for the diagnosis (molecular imaging) and radionuclide therapy of cancer.
Fischer, Christiane Anke
core +1 more source
Molecular Pathways: HER3 Targeted Therapy [PDF]
Clinical Cancer Research, 2014 Abstract The HER family of receptor tyrosine kinases, including EGF receptor (EGFR), HER2, HER3, and HER4, transduce growth-promoting signals in response to ligand binding to their extracellular domains (ECD). This family is deregulated in numerous cancers, with mutations in EGFR and HER2 often serving as “driver” events to activate key ...
Kinisha, Gala, Sarat, Chandarlapaty
openaire +2 more sources
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono +7 more
wiley +1 more source
Journal of Pancreatology, 2023 The clinical use of nuclear medicine imaging and therapy in pancreatic neuroendocrine tumors has been greatly strengthened since the approval of 68Ga-DOTATATE and 177Lu-DOTATATE. However, many aspects are still under discussion.
Wenjia Zhu, Meixi Liu, Li Huo
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
BMC CancerSqualene epoxidase (SQLE) drives hepatocellular carcinoma (HCC) development via increased hepatic oxidative stress, a hallmark of ferroptosis. Although investigations have progressed, the precise link between SQLE and ferroptosis in HCC remains ...
Xun Yang +6 more
doaj +1 more source
Frontiers in Oncology, 2021 BackgroundEctopic adrenocorticotropic hormone (ACTH)-secreting lung tumors represent the most common cause of ectopic Cushing syndrome (ECS). Pulmonary opportunistic infections are associated with ECS.
Guozhu Hou +7 more
doaj +1 more source