Results 71 to 80 of about 2,123,606 (402)
Future Options of Molecular-Targeted Therapy in Small Cell Lung Cancer
Cancers, 2019 Lung cancer is the leading cause of cancer-related deaths worldwide. With a focus on histology, there are two major subtypes: Non-small cell lung cancer (NSCLC) (the more frequent subtype), and small cell lung cancer (SCLC) (the more aggressive one ...
A. Schulze +6 more
semanticscholar +1 more source
Molecular-targeted therapy for cancer
Chinese Journal of Cancer, 2010 Molecular-targeted therapy is a newly developed approach for cancer therapy. With the advantages of lower side effects and higher performance, this approach has become a critical focus of cancer research. There are various molecules that can be treated as therapeutic targets for cancer.
Bing Dong, Yimin Zhu
openaire +3 more sources
Management of imatinib-resistant CML patients [PDF]
, 2007 Imatinib has had marked impact on outcomes in chronic myelogenous leukemia (CML) patients for all stages of the disease and is endorsed by international treatment guidelines as the first line option.
Branford S +21 more
core +1 more source
What role does pyroptosis play in cancer?
Molecular Metabolism, 2022 Background: Pyroptosis has been attracting much attention recently. We have briefly compared its differences and similarities with other programmed deaths and the process of its study. With further exploration of the caspase family, including caspase-1/3/
Chen Huang, Jian Li, Chenliang Zhang
doaj
Frontiers in Oncology, 2021 BackgroundEctopic adrenocorticotropic hormone (ACTH)-secreting lung tumors represent the most common cause of ectopic Cushing syndrome (ECS). Pulmonary opportunistic infections are associated with ECS.
Guozhu Hou +7 more
doaj +1 more source
Molecular targeted therapy of BRAF-mutant colorectal cancer
Therapeutic Advances in Medical Oncology, 2019 Over the past two decades, the molecular characterization of metastatic colorectal cancer (mCRC) has been revolutionized by the routine implementation of RAS and BRAF tests.
M. Ducreux +9 more
semanticscholar +1 more source
Targeted therapies in the management of locally advanced and metastatic pancreatic cancer: a systematic review [PDF]
, 2018 Pancreatic cancer has a dismal prognosis particularly in patients presenting with unresectable tumors. We performed a bibliometric analysis of clinical trials for pancreatic cancer conducted between 2014-2016 focusing on patients that presented with ...
Biankin, Andrew V. +3 more
core +1 more source
Frontiers in Oncology, 2021 BackgroundMolecular imaging targeting angiogenesis can specifically monitor the early therapeutic effect of antiangiogenesis therapy. We explore the predictive values of an integrin αvβ3-targeted tracer, 99mTc-PEG4-E[PEG4-c(RGDfK)]2 (99mTc-3PRGD2), for ...
Xiaona Jin +13 more
doaj +1 more source
Clinical Development of Molecular Targeted Therapy in Head and Neck Squamous Cell Carcinoma
JNCI Cancer Spectrum, 2019 A better understanding of cancer biology has led to the development of molecular targeted therapy, which has dramatically improved the outcome of some cancer patients, especially when a biomarker of efficacy has been used for patients’ selection. In head
P. Gougis +7 more
semanticscholar +1 more source
Ribosomal proteins and human diseases: molecular mechanisms and targeted therapy
Signal Transduction and Targeted Therapy, 2021 Ribosome biogenesis and protein synthesis are fundamental rate-limiting steps for cell growth and proliferation. The ribosomal proteins (RPs), comprising the structural parts of the ribosome, are essential for ribosome assembly and function.
Jian Kang +5 more
semanticscholar +1 more source