Results 31 to 40 of about 945 (112)

Synthesis and DFT studies of molybdopterin containing model complexes

open access: yes, 2007
In der vorliegenden Arbeit wurden Modellsysteme für molybopterinhaltige Enzyme untersucht. Dazu wurden Molybdän- und Wolframkomplexe mit verschiedenen Liganden synthetisiert und mit Methoden der ...
Starke, Kerstin   +7 more
core   +1 more source

The Aspergillus nidulans cnxF gene and its involvement in molybdopterin biosynthesis. Molecular characterisation and analysis of in vivo generated mutants

open access: yes, 1998
The product of the Aspergillus nidulans cnxF gene was found by biochemical analysis of cnxF mutants to be involved in the conversion of precursor Z to molybdopterin, Mutants cnxF1242 and cnxF8 accumulate precursor Z, while the level of molybdopterin is ...
2, other   +4 more
core   +3 more sources

Room‐temperature crystal structure of a metal‐dependent W‐formate dehydrogenase by serial synchrotron crystallography

open access: yesActa Crystallographica Section D, Volume 82, Issue 9, Page 1072-1081, September 2026.
We report a room‐temperature serial synchrotron X‐ray crystallographic structural analysis of Nitratidesulfovibrio vulgaris formate dehydrogenase AB, an enzyme that reduces CO2 to formate.Metal‐dependent formate dehydrogenases (Fdhs) are a promising research target in efforts to mitigate climate change by developing active, efficient, selective and ...
Guilherme Vilela-Alves   +7 more
wiley   +1 more source

Which functional groups of the molybdopterin ligand should be considered when modeling the active sites of the molybdenum and tungsten cofactors? A density functional theory study. [Elektronisk resurs] [PDF]

open access: yes, 2009
A density functional theory study of the influence of the various functional groups of the molybdopterin ligand on electronic and geometric properties of active-site models for the molybdenum and tungsten cofactors has been undertaken.
Ryde, Ulf,   +3 more
core   +2 more sources

Genomic Insights Into the Multimetal Resilience and Biofilm‐Templated Nanorod Biosynthesis of Stenotrophomonas bentonitica BII‐R7: Bioremediation and Green Nanotechnology Implications

open access: yesMicrobial Biotechnology, Volume 19, Issue 9, September 2026.
Biofilm extracellular polymeric substances (EPS) in Stenotrophomonas bentonitica BII‐R7 direct the formation of crystalline trigonal selenium nanorods. Comparative genomics identifies a unique genetic toolkit underpinning EPS composition and metal resilience, positioning this strain as a platform for bioremediation and green nanomaterial synthesis ...
Eduardo Perez‐Muelas   +6 more
wiley   +1 more source

Cleavage of the moaX-encoded fused molybdopterin synthase from Mycobacterium tuberculosis is necessary for activity [PDF]

open access: yes, 2015
Background: Molybdopterin cofactor (MoCo) biosynthesis in Mycobacterium tuberculosis is associated with a multiplicity of genes encoding several enzymes in the pathway, including the molybdopterin (MPT) synthase, a hetero tetramer comprising two MoaD and
Kana, Bavesh D   +3 more
core   +1 more source

Rearrangement reactions in the biosynthesis of molybdopterin [PDF]

open access: yesEuropean Journal of Biochemistry, 1998
The genes moaABC of Escherichia coli were ligated into the expression vector pNCO113. The resulting plasmid was transformed into a moeA mutant of E. coli. From cultures of the recombinant strain, a pteridine designated compound Z could be isolated at 5 mg/liter. Compound Z is a product of precursor Z, a biosynthetic precursor of molybdopterin. Cultures
C, Rieder   +8 more
openaire   +2 more sources

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, Volume 600, Issue 15, Page 2094-2107, August 2026.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Molybdopterin biosynthesis pathway contributes to the regulation of SaeRS two-component system by ClpP in Staphylococcus aureus [PDF]

open access: yes, 2022
In Staphylococcus aureus, the SaeRS two-component system is essential for the bacterium’s hemolytic activity and virulence. The Newman strain of S. aureus contains a variant of SaeS sensor kinase, SaeS L18P.
Li, Qian   +20 more
core   +1 more source

Understanding the Catalytic Determinant role of Diaphorase‐Like Subunit in Formate Dehydrogenases via Redox Couples

open access: yesAdvanced Science, Volume 13, Issue 46, 17 August 2026.
A unique mechanism of catalytic bias regulated by diaphorase‐like subunit in formate dehydrogenase from Rhodobacter aestuarii is revealed. The diaphorase‐like subunit functions act as a biological “voltage rheostat” that controls the slow release of NADH to regulate redox balance, biasing the enzyme's catalytic preference toward CO2 reduction over ...
Kuncheng Zhang   +7 more
wiley   +1 more source

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