Results 101 to 110 of about 6,030,936 (310)

Monitoring data-driven dynamic safety assessment framework for deep foundation pit construction based on grey clustering and moment method

Frontiers in Earth Science
To address the safety challenges of deep foundation pit construction under complex conditions, this study proposes a dynamic assessment framework based on grey clustering theory and a moment estimation composite weighting method.
Pengliang Dang, Zeliang Li, Dehai Zou, Hangjun Li, Zilong Cheng, Le Chang, Yadong Lu   +6 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Socioeconomic Inequalities in Total and Site-Specific Cancer Incidence in Germany: A Population-Based Registry Study

Frontiers in Oncology, 2018
Most chronic diseases follow a socioeconomic gradient with higher rates in lower socioeconomic groups. A growing body of research, however, reveals cancer to be a disease group with very diverse socioeconomic patterning, even demonstrating reverse ...
Jens Hoebel, Lars E. Kroll, Julia Fiebig, Thomas Lampert, Alexander Katalinic, Benjamin Barnes, Klaus Kraywinkel   +6 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Abnormal Monitoring Data Detection Based on Matrix Manipulation and the Cuckoo Search Algorithm

Mathematics
Structural health monitoring is an effective method to evaluate the safety status of dams. Measurement error is an important factor which affects the accuracy of monitoring data modeling.
Zhenzhu Meng, Yiren Wang, Sen Zheng, Xiao Wang, Dan Liu, Jinxin Zhang, Yiting Shao   +6 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Potentially toxic cyanobacteria in Trentino lakes: bloom episodes detected by monitoring data over the last ten years

Advances in Oceanography and Limnology
This short note illustrates some algal blooms caused by potentially toxic cyanobacteria in water bodies in the NE Alps, focusing in particular on the last ten years.
Sabrina Pozzi, Silvia Costaraoss, Giovanna Pellegrini   +2 more
doaj   +1 more source

Data for monitoring the poverty MDG [PDF]

human development, millennium development goals ...
Angus Deaton
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source