Results 81 to 90 of about 2,173,093 (267)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Study on Deformation Control of Road-Deep Foundation Pit Passing under Elevated Subway Bridge

Applied Sciences
This paper focuses on the application of pile foundation underpinning technology in a deep foundation pit of a subway Viaduct Project in Beijing. The study aims to address the engineering characteristics of the project, including a large number of new ...
Hua Peng, Bowen Meng, Sui Tan, Li Zhu, Guan Wang   +4 more
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Estimation of the stability of tailings dams based on genetic algorithm-supported calibration results and monitoring data

Studia Geotechnica et Mechanica
In consideration of the potential consequences, ensuring the safety of tailings dams is of paramount importance. A probable failure mechanism is the loss of global stability, which, in certain cases, may involve shearing within the subsoil. A significant
Grosel Szczepan
doaj   +1 more source

Predicting the Deformation of a Slope Using a Random Coefficient Panel Data Model

Fractal and Fractional
Engineering constructions in coastal areas not only affect existing landslides, but also induce new landslides. Variation of the water level makes the coastal area a geological hazard-prone.
Zhenxia Yuan, Yadong Bian, Weijian Liu, Fuzhou Qi, Haohao Ma, Sen Zheng, Zhenzhu Meng   +6 more
doaj   +1 more source

Optimizing Location of Car-Sharing Stations Based on Potential Travel Demand and Present Operation Characteristics: The Case of Chengdu

Journal of Advanced Transportation, 2019
Car-sharing is becoming an increasingly popular travel mode in China and many companies invest plenty of money on that including vehicle enterprises and Internet companies.
Yu Cheng, Xu Chen, Xiaohua Ding, Linting Zeng   +3 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

A Study on Water Quality Characteristics and Classification Scheme for Improving Major Tributaries in Sejong Special Self-Governing City: Development and Application of a Monthly Water Quality Index [PDF]

대한환경공학회지
This study performed a comprehensive assessment of water quality in four major tributaries - Yeongicheon, Samsungcheon, Bangchukcheon, and Jecheon - in Sejong Special Self-Governing City. The aim was to guide the development of effective river management
Chan-Ju Park, Sung-Suk Jung, Chang-Suk You, Seung-Gu Kang, Jang-Hee Lee, Jae-Hyuk Choi, Mi-Hye Ahn, Jung-Woo Ryu, Jin-Gyun Eom, Eun-Ok Bang, Kyung-Duk Zoh, Kyong-Yong Jung   +11 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source