Results 11 to 20 of about 9,277,402 (300)

The Infectious Diseases Consequences of Monkey Business [PDF]

Canadian Journal of Infectious Diseases and Medical Microbiology, 2008
Many microorganisms that affect humans have originated in animal species and have subsequently evolved to afflict humans (1). Many factors may contribute to the ability of infectious agents to cross the species barrier and include those related to the ...
JM Conly, BL Johnston
doaj   +7 more sources

Inferring collective dynamical states from widely unobserved systems [PDF]

Wilting, J. & Priesemann, V. Inferring collective dynamical states from widely unobserved systems. Nature Communications 9, 2325 (2018), 2018
When assessing spatially-extended complex systems, one can rarely sample the states of all components. We show that this spatial subsampling typically leads to severe underestimation of the risk of instability in systems with propagating events.
Priesemann, Viola, Wilting, Jens
core   +2 more sources

Generation of a Hutchinson–Gilford progeria syndrome monkey model by base editing

Protein & Cell, 2020
Many human genetic diseases, including Hutchinson-Gilford progeria syndrome (HGPS), are caused by single point mutations. HGPS is a rare disorder that causes premature aging and is usually caused by a de novo point mutation in the LMNA gene. Base editors
Fang Wang, Weiqi Zhang, Qiaoyan Yang, Yu Kang, Yanling Fan, Jingkuan Wei, Zunpeng Liu, Shaoxing Dai, Hao Li, Zifan Li, Lizhu Xu, Chu Chu, Jing Qu, Chenyang Si, Weizhi Ji, Guang-Hui Liu, Chengzu Long, Yuyu Niu   +17 more
doaj   +2 more sources

Renal Disease in Squirrel Monkeys (Saimiri sciureus) [PDF]

Veterinary Pathology, 1981
Renal lithiasis, pyelonephritis, and glomerulonephritis were common in our colony of Brazilian phenotype squirrel monkeys (Saimiri sciureus), with glomerulonephritis being a major cause of mortality in adult animals. Squirrel monkey glomerulonephritis was divided into four major classifications, based on light and electron microscopy, similar to those
Harold F. Stills, Bill C. Bullock
openalex   +3 more sources

Monkey hybrid stem cells develop cellular features of Huntington's disease [PDF]

BMC Cell Biology, 2010
Background Pluripotent stem cells that are capable of differentiating into different cell types and develop robust hallmark cellular features are useful tools for clarifying the impact of developmental events on neurodegenerative diseases such as ...
Lorthongpanich Chanchao, Johnson Zach, Yang Shang-Hsun, Snyder Brooke R, Cheng Pei-Hsun, Cheng Eric CH, Laowtammathron Chuti, Kuo Hung-Chih, Parnpai Rangsun, Chan Anthony WS   +9 more
doaj   +2 more sources

Lessons on Non-Progression of HIV Disease from Monkeys [PDF]

Frontiers in Immunology, 2013
Rhesus macaques infected with simian immunodeficiency virus (SIV) represent the most widely used model for studies related to understanding infection, pathology, immunology, and intervention strategies for HIV infection and AIDS in humans. This model recapitulates the significant impact of host immunogenetics and inter-individual variations on the ...
Pramod N. Nehete, Shailbala Singh, K. Jagannadha Sastry   +2 more
openalex   +5 more sources

Molecular determinants of neuroprotection in blood-brain interfaces of the cynomolgus monkey [PDF]

Frontiers in Pharmacology
The blood-brain barrier (BBB) formed by the cerebral microvessel endothelium and the blood-CSF barrier (BCSFB) formed by the choroid plexus epithelium impact the cerebral bioavailability of drugs and endogenous molecules that contribute to ...
Nathalie Strazielle, Nathalie Strazielle, Sandrine Blondel, Joachim Confais, Rita El Khoury, Hugues Contamin, Jean-François Ghersi-Egea   +6 more
doaj   +2 more sources

A single-cell transcriptomic landscape of primate arterial aging

Nature Communications, 2020
Our understanding of how aging affects the cellular and molecular components of the vasculature and contributes to cardiovascular diseases is still limited.
Weiqi Zhang, Shu Zhang, Pengze Yan, Jie Ren, Moshi Song, Jingyi Li, Jinghui Lei, Huize Pan, Si Wang, Xibo Ma, Shuai Ma, Hongyu Li, Fei Sun, Haifeng Wan, Wei Li, Piu Chan, Qi Zhou, Guang-Hui Liu, Fuchou Tang, Jing Qu   +19 more
doaj   +2 more sources

Designing a solar powered automatic hand-dryer to combat the outbreak of ebola and monkey pox diseases in sub-Saharan Africa

Journal of Applied Sciences and Environmental Management, 2018
In recent times, the outbreak and the concomitant spread of Monkey pox and Ebola virus diseases across some countries of sub-Saharan Africa in electrifying waves was terrifying. The countries worst hit are Liberia, Sierra Leone, Ghana, and Nigeria.
U.K. Okpeki, A.O. Oyubu, A.U. Oyubu
doaj   +3 more sources

A Data-Driven Biophysical Computational Model of Parkinson's Disease based on Marmoset Monkeys [PDF]

IEEE Access, 2021, 2021
In this work we propose a new biophysical computational model of brain regions relevant to Parkinson's Disease based on local field potential data collected from the brain of marmoset monkeys. Parkinson's disease is a neurodegenerative disorder, linked to the death of dopaminergic neurons at the substantia nigra pars compacta, which affects the normal ...
arxiv   +1 more source