Results 51 to 60 of about 65,278 (164)

Efficient AAV8 delivery to the liver via isolated hepatic perfusion and analysis of hepatic lobule transduction patterns

Liver Research
Background and aims: Adeno-associated virus (AAV) is becoming an attractive vector due to its low toxicity and minimal immunogenicity. However, liver-targeted AAV gene therapy still faces challenges, such as low delivery efficiency and safety risks ...
Chao Wang, Mingming Fan, Jianrong Liu, Xiaolu Guo, Zhipeng Tan, Xueying Huang, Zhuoran Li, Xiaomei Liu, Ye Zhang, Jianqi Feng, Rui Fang, Li Wang, Qiong Ke   +12 more
doaj   +1 more source

Simian virus 40 in humans

Infectious Agents and Cancer, 2007
Simian virus 40 (SV40) is a monkey virus that was administered to human populations by contaminated vaccines which were produced in SV40 naturally infected monkey cells.
Tognon Mauro, Pancaldi Cecilia, Sabbioni Silvia, Balatti Veronica, Corallini Alfredo, Martini Fernanda   +5 more
doaj   +1 more source

Molecular determinants of neuroprotection in blood-brain interfaces of the cynomolgus monkey

Frontiers in Pharmacology
The blood-brain barrier (BBB) formed by the cerebral microvessel endothelium and the blood-CSF barrier (BCSFB) formed by the choroid plexus epithelium impact the cerebral bioavailability of drugs and endogenous molecules that contribute to ...
Nathalie Strazielle, Nathalie Strazielle, Sandrine Blondel, Joachim Confais, Rita El Khoury, Hugues Contamin, Jean-François Ghersi-Egea   +6 more
doaj   +1 more source

A complicated form of spontaneous aortic atherosclerosis in an African green monkeys (Chlorocebus aethiops sabaeus) male. Clinical case

Revista Científica
Atherosclerosis is the mechanistic basis of cardiovascular disorders manifested by damage to the walls of the aorta, coronary, cerebral and peripheral arteries, leading to the development of acute or chronic ischemia of internal organs and tissues. This
Sergey Orlov, Andrey Panchenko, Viktor Shestakov, Artem Oganesian, Yulia Kolesnik, David Ilyazyants, Elena Radomskaya, Tamara Fedotkina, Dmitry Bulgin, Leonid Churilov   +9 more
doaj   +1 more source

Establishment of a novel cynomolgus monkey model of hyperuricemia

Animal Models and Experimental Medicine
Background Chronic hyperuricemia is associated with complications such as gout and uric acid nephropathy, but uric acid also exhibits biological activities (e.g., antioxidant effects, potential neuroprotective properties against neurodegenerative ...
Ji‐Wei Wang, Le Zhang, Can Yang, Guan‐Cong Luo, Rui‐Chang Liu, Yan‐Jun Xu, Sheng Cheng, Wen‐Yu Jiang, Richard Ward, Yang Yang, Cheng Xiang, Shu An, Tian‐Rui Xu   +12 more
doaj   +1 more source

Impact of appetitive and aversive outcomes on brain responses: Linking the animal and human literatures

Frontiers in Systems Neuroscience, 2014
Decision-making is motivated by the possibility of obtaining reward and/or avoiding punishment. Though many have investigated behavior associated with appetitive or aversive outcomes, few have examined behaviors that rely on both.
Gregory B Bissonette, Ronny N Gentry, Srikanth ePadmala, Luiz ePessoa, Matthew R Roesch   +4 more
doaj   +1 more source

The Impacts of COVID-19 Lockdown on Human–Primate Coexistence: Insights and Recommendations

Ecosystem Health and Sustainability
The global outbreak of the COVID-19 pandemic has led to a series of human lockdowns. Studying human–animal linkages during these periods is essential in conserving global biodiversity, maintaining ecosystem integrity, and preventing zoonotic diseases ...
Junjie Li, Yihao Fang, Na Li, Canbin Huang, Yanpeng Li, Zhipang Huang, Ruliang Pan, Wen Xiao   +7 more
doaj   +1 more source

The influence of the nematode Eustrongylides excisus (Jägerskiöld, 1990) on the body of monkеy goby (Neogobius fluviatilis Pallas, 1814) caught in the lower part of the Dnipro (Zaporizhzhia) Reservoir

Ribogospodarsʹka Nauka Ukraïni
Purpose. To determine the specifics of the influence of the parasitic nematode Eustrongylides excisus on the physiological and biochemical parameters of monkey goby (Neogobius fluviatilis) in the conditions of the lower reach of the Dnipro reservoir ...
V. Sydorenko, O. Marenkov
doaj   +1 more source

First evidence of transovarial transmission of Kyasanur Forest disease virus in Haemaphysalis and Rhipicephalus ticks in the wild

Parasites & Vectors
Background Kyasanur forest disease virus (KFDV) is a tick-borne flavivirus causing debilitating and potentially fatal disease in people in the Western Ghats region of India.
Sarah J. Burthe, Bhimanagoud Kumbar, Stefanie M. Schäfer, Bethan V. Purse, Abi T. Vanak, Natrajan Balakrishnan, Richard Hassall, Subhash L. Hoti, Darshan Narayanaswamy, Santoshkumar Potadar, Mujeeb Rahman, Mohammed Mudassar Chanda   +11 more
doaj   +1 more source

Spontaneous tauopathy with parkinsonism in an aged cynomolgus macaque. [PDF]

Front Aging Neurosci
Takahashi M, Taniguchi D, Funayama M, Cioffi E, Fukuyama S, Ito T, Nakajima T, Tsuyama K, Li Y, Ishiko S, Chiken S, Nakajima A, Hatano T, Tasaki Y, Hasegawa K, Shimo Y, Nambu A, Hattori N, Takakusaki K.   +18 more
europepmc   +1 more source