Results 121 to 130 of about 31,825 (297)

Organoid Models to Study Human Infectious Diseases

Cell Proliferation, EarlyView.
Our manuscript reviews the role of organoids as models for studying human infectious diseases, highlighting their irreplaceable contributions to drug testing and vaccine development for significant infectious diseases including HIV, ZIKV, SARS‐CoV‐2 and MPXV.
Sijing Zhu, Dan Chen, Xinzhi Yang, Liuliu Yang, Yuling Han   +4 more
wiley   +1 more source

Detection of Monkeypox Disease from Human Skin Images with a Hybrid Deep Learning Model

Diagnostics, 2023
Monkeypox, a virus transmitted from animals to humans, is a DNA virus with two distinct genetic lineages in central and eastern Africa. In addition to zootonic transmission through direct contact with the body fluids and blood of infected animals ...
Fatih Uysal
semanticscholar   +1 more source

Treatment and prevention of monkeypox

Enfermedades infecciosas y microbiologia clinica (English ed.), 2023
Monkeypox is a zoonosis that is spread mainly through direct contact with fluids and skin lesions of infected people with vesicles still active. Although the virus was isolated for the first time in 1958 and the first human case was identified in a child in 1970, in the Democratic Republic of the Congo, the disease has progressively increased its ...
de la Calle-Prieto, Fernando, Estébanez Muñoz, Miriam, Ramírez, Germán, Díaz-Menéndez, Marta, Velasco, María, Azkune Galparsoro, Harkaitz, Salavert Lletí, Miguel, Mata Forte, Tatiana, Blanco, José Luis, Mora-Rillo, Marta, Arsuaga, Marta, de Miguel Buckley, Rosa, Arribas, Jose Ramón, Membrillo, Francisco Javier   +13 more
openaire   +3 more sources

Expression and functional characterisation of Variola and Monkeypox virus tumour necrosis factor receptor (TNFR) proteins [PDF]

, 2012
University of Technology, Sydney. Faculty of Science.Tumour necrosis factor-a (TNFα) is a pleiotropic cytokine that plays a critical role in cellular response to virus infection. Virtually all poxviruses encode genes that are homologous to human tumour
Sherwood, S
core  

Epithelial Immunization Induces Polyfunctional CD8+ T Cells and Optimal Mousepox Protection. [PDF]

, 2014
We assessed several routes of immunization with vaccinia virus (VACV) in protecting mice against ectromelia virus (ECTV). By a wide margin, skin scarification provided the greatest protection. Humoral immunity and resident-memory T cells notwithstanding,
A. E. Snook, A. R. Hersperger, B. C. DeHaven, Betts, Betts, Buller, Burnet, Earl, Edghill-Smith, Esteban, Fenner, Gebhardt, Hersperger, Hersperger, Hooper, Jiang, L. C. Eisenlohr, Liu, Liu, Makedonas, N. A. Siciliano, Panchanathan, Panchanathan, Panchanathan, Seder, Trentin, Tscharke, Xu   +27 more
core   +2 more sources

Vaccination in dermatology 2025: Update considering current recommendations of the German Standing Committee on Vaccination

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary The immunosuppressive and immunomodulatory treatment of dermatological patients necessitates the regular review and updating of standard vaccinations and vaccines indicated for specific conditions. The German Standing Committee on Vaccination (STIKO) at the Robert Koch Institute regularly publishes evidence‐based vaccination recommendations ...
Johanna Stoevesandt, Marc Schmalzing, Sophia Mohme, Matthias Goebeler   +3 more
wiley   +1 more source

Immunization with a single extracellular enveloped virus protein produced in bacteria provides partial protection from a lethal orthopoxvirus infection in a natural host [PDF]

, 2006
Subunit vaccines that use the vaccinia virus extracellular envelope protein A33R alone or combined with other structural proteins are excellent candidates for a new smallpox vaccine.
Alcami, Alcami, Appleyard, Belyakov, Blanden, Blanden, Blanden, Blasco, Buller, Chen, Cono, Cunha, DiGiulio, Earl, Fenner, Fenner, Fenner, Fogg, Fulginiti, Galmiche, Henderson, Hong Cheng, Hooper, Hooper, Hutin, Karupiah, Kempe, Luis J. Sigal, Lustig, Min Fang, Moss, Niemialtowski, Norbury, Payne, Payne, Roper, Scholtz, Shchelkunov, Shchelkunov, Smith, Smith, Tscharke, van Holde, Vanderplasschen, Wolint, Zhongping Dai, Zimei Bu   +46 more
core   +1 more source

A guide to heat shock factors as multifunctional transcriptional regulators

The FEBS Journal, EarlyView.
The heat shock factors (HSFs) are evolutionarily conserved transcription factors best known as regulators of molecular chaperone genes in response to heat shock and other protein‐damaging stresses. Vertebrate HSFs, HSF1‐5, HSFX, and HSFY, are implicated in various physiological and pathological processes, including organismal development and cancer ...
Hendrik S. E. Hästbacka, Alejandro J. Da Silva, Lea Sistonen, Eva Henriksson   +3 more
wiley   +1 more source

Monkeypox: epidemiology, pathogenesis, treatment and prevention

Signal Transduction and Targeted Therapy, 2022
Monkeypox is a zoonotic disease that was once endemic in west and central Africa caused by monkeypox virus. However, cases recently have been confirmed in many nonendemic countries outside of Africa.
Yong Huang, Li Mu, Wei Wang
doaj   +1 more source

Diagnostic electron microscopy in human infectious diseases – Methods and applications

Journal of Microscopy, EarlyView.
Abstract Diagnostic electron microscopy (EM) is indispensable in all cases of infectious diseases which deserve or profit from the detection of the entire pathogen (i.e. the infectious unit). The focus of its application has shifted during the last decades from routine diagnostics to diagnostics of special cases, emergencies and the investigation of ...
Michael Laue
wiley   +1 more source