Results 51 to 60 of about 1,689,796 (314)

Optimal control model of human-to-human transmission of monkeypox virus

F1000Research, 2023
Background: The number of monkeypox cases is rising globally, but it’s unclear how many instances there will be in the near future. The disease has been one of the major problems for sub-Saharan Africans in the past few years.
J. Ackora-Prah, S. Okyere, E. Bonyah, A. Adebanji, Y. Boateng   +4 more
semanticscholar   +1 more source

Characterizing the transmission potential of zoonotic infections from minor outbreaks. [PDF]

, 2015
The transmission potential of a novel infection depends on both the inherent transmissibility of a pathogen, and the level of susceptibility in the host population.
Edmunds, W John, Kucharski, Adam J
core   +1 more source

Immunoinformatic-based design of immune-boosting multiepitope subunit vaccines against monkeypox virus and validation through molecular dynamics and immune simulation

Frontiers in Immunology, 2022
Monkeypox virus is the causative agent of monkeypox disease, belonging to an orthopoxvirus genus, with a disease pattern similar to that of smallpox. The number of monkeypox cases have robustly increased recently in several countries around the world ...
Muhammad Suleman, Farooq Rashid, Shahid Ali, Hassan Sher, Sisi Luo, Sisi Luo, Sisi Luo, Liji Xie, Liji Xie, Liji Xie, Zhixun Xie, Zhixun Xie, Zhixun Xie   +12 more
doaj   +1 more source

Distinct monkeypox virus lineages co-circulating in humans before 2022

Nature Network Boston, 2023
Analysis of monkeypox virus (MPXV) isolates circulating in Nigeria before the 2022 global outbreak of MPXV sheds light on the diversification of the virus that eventually gave rise to the 2022 MPXV lineage.
Nnaemeka Ndodo, Jonathan W Ashcroft, Kuiama Lewandowski, A. Yinka-Ogunleye, Chimaobi Chukwu, Adama Ahmad, David King, Afolabi Akinpelu, Carlos Maluquer de Motes, Paolo Ribeca, Rebecca P. Sumner, A. Rambaut, M. Chester, Thomas Maishman, O. Bamidele, N. Mba, Olajumoke Babatunde, O. Aruna, S. Pullan, Ben Gannon, Colin S. Brown, C. Ihekweazu, I. Adetifa, David O. Ulaeto   +23 more
semanticscholar   +1 more source

Proteomic basis of the antibody response to monkeypox virus infection examined in cynomolgus macaques and a comparison to human smallpox vaccination. [PDF]

PLoS ONE, 2010
Monkeypox is a zoonotic viral disease that occurs primarily in Central and West Africa. A recent outbreak in the United States heightened public health concerns for susceptible human populations.
Sarah Keasey, Christine Pugh, Alexander Tikhonov, Gengxin Chen, Barry Schweitzer, Aysegul Nalca, Robert G Ulrich   +6 more
doaj   +1 more source

In silico design and immunoinformatics analysis of a universal multi-epitope vaccine against monkeypox virus

PLoS ONE, 2023
Monkeypox virus (MPXV) outbreaks have been reported in various countries worldwide; however, there is no specific vaccine against MPXV. In this study, therefore, we employed computational approaches to design a multi-epitope vaccine against MPXV ...
Samira Sanami, Shahin Nazarian, Sajjad Ahmad, E. Raeisi, Muhammad Tahir ul Qamar, Shahram Tahmasebian, Hamidreza Pazoki-Toroudi, M. Fazeli, Mahdi Ghatreh Samani   +8 more
semanticscholar   +1 more source

Ultrasensitive and Specific Clustered Regularly Interspaced Short Palindromic Repeats Empowered a Plasmonic Fiber Tip System for Amplification-Free Monkeypox Virus Detection and Genotyping

ACS Nano, 2023
The urgent necessity for highly sensitive diagnostic tools has been accentuated by the ongoing mpox (monkeypox) virus pandemic due to the complexity in identifying asymptomatic and presymptomatic carriers.
Yuzhi Chen, Zhi Chen, Tianzhong Li, M. Qiu, Jinghan Zhang, Yan Wang, W. Yuan, A. Ho, O. Al-Hartomy, S. Wageh, A. Al-sehemi, Xin Shi, Jingfeng Li, Zhongjian Xie, Li Xuejin, Han Zhang   +15 more
semanticscholar   +1 more source

Development of multi-epitope vaccines against the monkeypox virus based on envelope proteins using immunoinformatics approaches

Frontiers in Immunology, 2023
Background Since May 2022, cases of monkeypox, a zoonotic disease caused by the monkeypox virus (MPXV), have been increasingly reported worldwide. There are, however, no proven therapies or vaccines available for monkeypox.
C. Tan, Fei Zhu, P. Pan, Anhua Wu, Chunhui Li   +4 more
semanticscholar   +1 more source

Elucidating the role of the complement control protein in monkeypox pathogenicity. [PDF]

PLoS ONE, 2012
Monkeypox virus (MPXV) causes a smallpox-like disease in humans. Clinical and epidemiological studies provide evidence of pathogenicity differences between two geographically distinct monkeypox virus clades: the West African and Congo Basin.
Paul N Hudson, Joshua Self, Sonja Weiss, Zachary Braden, Yuhong Xiao, Natasha M Girgis, Ginny Emerson, Christine Hughes, Scott A Sammons, Stuart N Isaacs, Inger K Damon, Victoria A Olson   +11 more
doaj   +1 more source

Anticipating the species jump: surveillance for emerging viral threats. [PDF]

, 2012
Zoonotic disease surveillance is typically triggered after animal pathogens have already infected humans. Are there ways to identify high-risk viruses before they emerge in humans? If so, then how and where can identifications be made and by what methods?
Bush, RM, Cobey, S, Flanagan, ML, Glass, GE, Leighton, TJ, Parrish, CR   +5 more
core   +1 more source