Results 91 to 100 of about 10,102 (222)

Comparative virology and pathology of Monkeypox virus in Syrian hamsters, C57BL/6, and BALB/c mice: A framework for preclinical model selection

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This study compared monkeypox virus (MPXV) infection in three small animal models: Syrian hamsters, C57BL/6 mice, and BALB/c mice. Following intraperitoneal inoculation, Syrian hamsters exhibited the highest susceptibility, with rapid systemic viral dissemination, elevated splenic and renal viral burdens, and severe histopathological damage, followed ...
Xiaohui Wei   +9 more
wiley   +1 more source

Characteristics of the monkeypox virus isolate obtained from the first patient in Russia and its sensitivity to 7-[N-(4-trifluoromethylbenzoyl)-hydrazinocarbonyl]-tricyclo-[3.2.2.0^2,4]non-8-en-6-carboxylic acid

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии
Introduction. Since early May 2022, more than 90,000 cases of monkeypox virus infection have been reported in more than 70 countries around the World. This is the largest outbreak of monkeypox ever recorded outside of Africa.
Alena S. Ovchinnikova   +13 more
doaj   +1 more source

Prevalence and Molecular Profiling of Merkel Cell Polyomavirus in Patients With Monkeypox Virus Infection

open access: yesJournal of Medical Virology, Volume 98, Issue 4, April 2026.
ABSTRACT Mpox, caused by Monkeypox virus (MPXV), is associated with mucosal involvement and immune modulation that may influence viral coinfections. Merkel Cell Polyomavirus (MCPyV), a ubiquitous virus capable of lifelong persistence, was investigated in 66 Mpox patients enrolled at Lazzaro Spallanzani National Institute for Infectious Diseases (Rome ...
Sara Passerini   +8 more
wiley   +1 more source

Emergence and dissemination of monkeypox, an intimidating global public health problem

open access: yesJournal of Infection and Public Health, 2022
The monkeypox virus (MPXV) is the cause of a zoonotic infection similar to smallpox. Although it is endemic to Africa, it has recently begun to circulate in other parts of the world.
Hasan Ejaz   +9 more
doaj   +1 more source

Monkeypox Outbreak: Wastewater and Environmental Surveillance Perspective [PDF]

open access: yes, 2022
Monkeypox disease (MPXD), a viral disease caused by monkeypox virus (MPXV), is an emerging zoonotic disease endemic in some countries of Central and Western Africa but seldom reported outside the affected region. Since May 2022, MPXD has been reported at
Adhikari, Sangeet   +16 more
core   +3 more sources

Mpox (Monkeypox) in Pregnancy Updates

open access: yesHealth Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background Mpox is a zoonotic viral disease caused by the monkeypox virus, with potential for significant morbidity across all population groups, including pregnant individuals and neonates. Pregnancy represents an immunologically vulnerable state, rendering affected mothers more susceptible to severe disease progression.
Yeshey Dorjey, Deep Kiran Chhetri
wiley   +1 more source

Phylogenomic and Structural Analysis of the Monkeypox Virus Shows Evolution towards Increased Stability

open access: yesViruses, 2022
Monkeypox is an infectious zoonotic disease caused by an Orthopoxvirus and results in symptoms similar to smallpox. In a recent outbreak, monkeypox virus (MPXV) cases have been reported globally since May 2022, and the numbers are increasing.
Priya Yadav   +2 more
doaj   +1 more source

Distinct monkeypox virus lineages co-circulating in humans before 2022 [PDF]

open access: yes, 2023
The 2022 global mpox outbreak raises questions about how this zoonotic disease established effective human-to-human transmission and its potential for further adaptation.
Adetifa, Ifedayo   +23 more
core   +3 more sources

Eczema Monkeypoxicum Following Sexual Transmission Treated With Tecovirimat

open access: yesJEADV Clinical Practice, Volume 5, Issue 1, Page 250-253, March 2026.
Capsule summary Mpox is a zoonotic infection that may present severe dissemination in patients with pre‐existing dermatoses. We report a 30‐year‐old man with active atopic dermatitis who developed extensive, sexually transmitted mpox with widespread cutaneous involvement consistent with eczema monkeypoxicum.
Andrés Vidal González   +6 more
wiley   +1 more source

Mpox Outbreak in the East Africa Region: Current Status, Containment Measures, Challenges, and Future Direction

open access: yesPublic Health Challenges, Volume 5, Issue 1, March 2026.
The WHO declares the Mpox outbreak a Public Health Emergency of International Concern, with the DRC as the epicenter in the EAC. DRC, Uganda, and Burundi experience extensive transmission; Kenya and Uganda show higher case fatality rates. Containment measures include surveillance, public awareness, infection prevention training, and vaccination (>73 ...
Reuben Sindayiheba   +9 more
wiley   +1 more source

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