Results 41 to 50 of about 10,102 (222)
An mRNA Vaccine Based on Antigens From Conserved Regions of Monkeypox Virus A35R and M1R With a Dimer-Like Conformation Confers Protection Against Both Monkeypox Virus and Vaccinia Virus Infections in Mice. [PDF]
MedComm (2020)We developed four candidate mRNA vaccine antigens based on conserved sequences of MPXV A35R and M1R proteins. Our findings demonstrate that the MV2 vaccine possesses favorable immunogenicity and prophylactic potential against MPXV and VACV infections, positioning it as a promising clinical candidate for MPXV prevention.
Tang C +14 more
europepmc +2 more sources
Journal of the Pakistan Medical Association, 2022 As the world is still under the grip of COVID-19, “WHO” has started alerting about the new global emergency due to a surge in cases of the Monkeypox virus (MPXV) disease (MPXD). MPXD is a rare viral zoonotic disease, caused by the monkeypox virus, which results in multiple centrifugal rashes similar to smallpox.
Mulazim Hussain Bukhari +1 more
openaire +2 more sources
A narrative review of pox: smallpox vs monkeypox
The Egyptian Journal of Internal Medicine, 2022 The famed variola (smallpox) virus and the monkeypox virus (MPXV) are closely related, and MPXV causes a milder form of febrile rash disease in people.
Samiksha Jayswal, Jagdish Kakadiya
doaj +1 more source
Animal Models Used in Monkeypox Research
Microorganisms, 2022 Monkeypox is an emerging zoonotic disease with a growing prevalence outside of its endemic area, posing a significant threat to public health. Despite the epidemiological and field investigations of monkeypox, little is known about its maintenance in ...
Marianna Domán +4 more
doaj +1 more source
Evolutionary potential of the monkeypox genome arising from interactions with human APOBEC3 enzymes. [PDF]
, 2023 APOBEC3, an enzyme subfamily that plays a role in virus restriction by generating mutations at particular DNA motifs or mutational hotspots, can drive viral mutagenesis with host-specific preferential hotspot mutations contributing to pathogen variation.
Anthony, Simon +5 more
core +1 more source
Globalization and Health, 2023 Background Outbreaks of monkeypox have been ongoing in non-endemic countries since May 2022. A thorough assessment of its global zoonotic niche and potential transmission risk is lacking.
Yan-Qun Sun +15 more
doaj +1 more source
Isolation of viable monkeypox virus from anal and urethral swabs, Italy, May to July 2022 [PDF]
, 2022 Anal and urethral samples from confirmed cases of monkeypox were screened for monkeypox virus (MPXV) by real-time PCR. Isolation of the virus was subsequently attempted in cell culture. Actively-replicating virus was demonstrated in 13 of 18 and 11 of 15
Antinori, Spinello +11 more
core +1 more source
"Virus Identification for Monkeypox in Human Seminal Fluid Samples: A Systematic Review" [PDF]
, 2023 Public health officials around the world are extremely concerned about the global outbreak of monkeypox (MPX), which has been claimed to have originated in Africa.
Barboza, Joshuan J. +7 more
core +2 more sources
Frontiers in Immunology, 2023 Monkeypox virus (MPXV) is a dsDNA virus, belonging to Poxviridae family. The outbreak of monkeypox disease in humans is critical in European and Western countries, owing to its origin in African regions.
Raghav Kataria +6 more
doaj +1 more source
Longitudinal virological and immunological profile in a case of human monkeypox infection [PDF]
, 2022 In a male with severe proctitis, monkeypox virus DNA was detected in skin lesions, blood, nasopharynx, and rectum, underlying the generalized viral spreading. Rectal involvement was still found when skin lesions disappeared.
Alberico Parente +15 more
core +1 more source