Results 161 to 170 of about 32,939 (178)
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Neurochemical Pathology, 1984
The presence of monoacylglycerol lipase was established in extracts of acetone-dried powders from rat and bovine brains using thioester substrate analogs. At pH 7.4, the apparent Km and Vmax values for 1-S-decanoyl-1-mercapto-2,3-propanediol were 56 microM and 227 nmol/h/mg protein in bovine gray matter.
J, Strosznajder, H, Singh, L A, Horrocks
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The presence of monoacylglycerol lipase was established in extracts of acetone-dried powders from rat and bovine brains using thioester substrate analogs. At pH 7.4, the apparent Km and Vmax values for 1-S-decanoyl-1-mercapto-2,3-propanediol were 56 microM and 227 nmol/h/mg protein in bovine gray matter.
J, Strosznajder, H, Singh, L A, Horrocks
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Monoacylglycerol from Punica granatum Seed Oil
Journal of Agricultural and Food Chemistry, 2001The seeds of Punica granatum, known as hap roman in the Arabian Peninsula, are commonly eaten as a dessert. As part of an ongoing project to find nonnutritional natural products which have health benefits, or that can be exploited to protect crops, the chloroform-soluble extract of the fermented seeds of P.
Majekodunmi O, Fatope +2 more
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Journal of Agricultural and Food Chemistry, 2014
The relationship between fatty acid composition of oils and their oxidative stability in the presence of monoacylglycerols was investigated. Purified vegetable oils were added at increasing amounts (0.5, 1, 2, and 3%) of monoacylglycerols obtained from purified soybean oil and submitted to an oven test (60 °C for 18 days). The obtained results showed a
Paradiso V. M. +5 more
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The relationship between fatty acid composition of oils and their oxidative stability in the presence of monoacylglycerols was investigated. Purified vegetable oils were added at increasing amounts (0.5, 1, 2, and 3%) of monoacylglycerols obtained from purified soybean oil and submitted to an oven test (60 °C for 18 days). The obtained results showed a
Paradiso V. M. +5 more
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Synthesis of a spin-labelled monoacylglycerol
Chemistry and Physics of Lipids, 1985Abstract Spin-labelled lipids are used in electron spin resonance (ESR) spectroscopy for studying microenvironments within biological membranes. Various classes are available, based on the use of N -oxyldimethyloxazolidinyl (or similar groups) as spin label. The synthesis is described of a new type of spin-labelled lipid, in which a monoacylglycerol
E.M. Fransen-Zeilstra, J.P. Ward
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Monoacylglycerol lipase (MAGL) as a promising therapeutic target
Biochemical Pharmacology, 2018Monoacylglycerol lipase (MAGL) has been characterized as the main enzyme responsible for the inactivation of the most abundant brain endocannabinoid, 2-arachidonoylglycerol (2-AG). Besides this role, MAGL has progressively acquired a growing importance as an integrative metabolic hub that controls not only the in vivo levels of 2-AG but also of other ...
Ana, Gil-Ordóñez +3 more
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Lipase-catalyzed syntheses of monoacylglycerols
Enzyme and Microbial Technology, 1995The application of lipases for the production of monoacylglycerols is reviewed. Glycerolysis or selective hydrolysis of fats and oils, esterification of fatty acids or esters with glycerol, and reactions employing protected glycerols are presented. From the most recent literature, reaction systems ranging from organic solvents to reverse micelles and ...
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Radioassay of the stereospecificity of 2-monoacylglycerol acyltransferase
Analytical Biochemistry, 1982Abstract The 2-monoacylglycerol acyltransferase (EC 2.3.1.22, acylglycerol palmitoyl transferase) catalyzes the synthesis of X -1,2-diacylglycerols from 2-monoacylglycerol and acyl CoA with an apparently variable stereochemical specificity. A microassay for determining the ratio of sn-1,2- and sn-2,3-diacylglycerols formed by the acylation of ...
F, Manganaro, A, Kuksis, J J, Myher
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Structuring of Chicken Fat by Monoacylglycerols
Journal of the American Oil Chemists' Society, 2016AbstractIn this study, we investigated the effect of monoacylglycerol (MAG) as a structuring agent on the physicochemical, microstructure and rheological properties of chicken fat. The fatty acid composition, oxidative stability, free fatty acids (FFA), slip melting point (SMP), solid fat content (SFC), kinetics of crystallization, microstructure and ...
Mehdi Naderi +2 more
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The Medicinal Chemistry of Agents Targeting Monoacylglycerol Lipase
Current Topics in Medicinal Chemistry, 2008Monoacylglycerol lipase (MAGL) has been recently proposed as the main enzymatic activity responsible for the in vivo hydrolysis of the most abundant endocannabinoid in the brain, the 2-arachidonoylglycerol (2-AG). The endocannabinoids, mainly anandamide (AEA) and 2-AG, are a class of lipid messengers that modulate a broad number of physiological ...
Alma, Viso +2 more
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Intestinal monoacylglycerol metabolism: regulation and function
2008Sn-2-MG is a major product of dietary lipid digestion, yet its intestinal metabolism has not been investigated beyond its anabolic processing. Recently, a potential for sn-2-MG catabolism in the enterocyte has been proposed. Thus, we examined the regulation of the two known MG metabolizing enzymes, monoacylglycerol acyltransferase (MGAT) and ...
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