Study on a Novel Cold-Active and Halotolerant Monoacylglycerol Lipase Widespread in Marine Bacteria Reveals a New Group of Bacterial Monoacylglycerol Lipases Containing Unusual C(A/S)HSMG Catalytic Motifs [PDF]
Frontiers in Microbiology, 2020 Monoacylglycerol lipases (MGLs) are present in all domains of life. However, reports on bacterial MGLs are still limited. Until now, reported bacterial MGLs are all thermophilic/mesophilic enzymes from warm terrestrial environments or deep-sea ...
Chun-Yang Li +2 more
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Identification of lipases with activity towards monoacylglycerol by criterion of conserved cap architectures [PDF]
Biochimica Et Biophysica Acta - Molecular and Cell Biology of Lipids, 2018 Monoacylglycerol lipases (MGL) are a subclass of lipases that predominantly hydrolyze monoacylglycerol (MG) into glycerol and fatty acid. MGLs are ubiquitous enzymes across species and play a role in lipid metabolism, affecting energy homeostasis and ...
Lina Riegler-Berket +2 more
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Lipase production from Bacillus safensis VC-6 isolated from the volcanic region of Copahue: optimization and functional genomic insights [PDF]
Frontiers in MicrobiologyExtremophilic microorganisms produce highly stable and industrial-grade enzymes with enhanced performance. Thermostable enzymes, such as lipases that catalyze the hydrolysis and esterification of lipids, are of great industrial interest due to their ...
Valeria Foronda +7 more
doaj +2 more sources
Cytoplasmic fungal lipases release fungicides from ultra-deformable vesicular drug carriers. [PDF]
PLoS ONE, 2012 The Transfersome® is a lipid vesicle that contains membrane softeners, such as Tween 80, to make it ultra-deformable. This feature makes the Transfersome® an efficient carrier for delivery of therapeutic drugs across the skin barrier.
Gero Steinberg
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Acta Pharmaceutica Sinica B, 2020 Monoacylglycerol lipase (MAGL) is a serine hydrolase that plays a crucial role catalysing the hydrolysis of monoglycerides into glycerol and fatty acids.
Hui Deng, Weimin Li
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Assay of Cellular Diacylglycerol and Monoacylglycerol Lipases
, 1998 Bryan A Wolf
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Lipases are differentially regulated by hormones to maintain free fatty acid homeostasis for insect brain development [PDF]
BMC BiologyBackground Free fatty acids (FFAs) play vital roles as energy sources and substrates in organisms; however, the molecular mechanism regulating the homeostasis of FFA levels in various circumstances, such as feeding and nonfeeding stages, is not fully ...
Yan-Xue Li +4 more
doaj +2 more sources
Journal of Lipid Research, 2016 It was hypothesized that under induced lipid malabsorption/maldigestion conditions, an enriched sn-1(3)-monoacylglycerol (MAG) oil may be a better carrier for n-3 long-chain PUFAs (LC-PUFAs) compared with triacylglycerol (TAG) from fish oil.
Cristina Cruz-Hernandez +10 more
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Spatially Resolved Mapping of Monoacylglycerol Lipase Activity in the Brain. [PDF]
ACS Chem NeurosciAbstract Visualizing signaling systems in the brain with high spatial resolution is critical to understand brain function and to develop therapeutics. Especially enzymes are often regulated on the post-translational level, resulting in a disconnect between protein levels and activity.
van der Vliet D +13 more
europepmc +7 more sources
Biochimica Et Biophysica Acta - Molecular and Cell Biology of Lipids, 2012 Monoacylglycerol lipases (MGLs) catalyse the hydrolysis of monoacylglycerol into free fatty acid and glycerol. MGLs have been identified throughout all genera of life and have adopted different substrate specificities depending on their physiological ...
Gustavo Arruda Bezerra +2 more
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