Results 41 to 50 of about 5,510 (189)

Experimental and Modeling Studies of the Reaction Kinetics of Alkaline-Catalyzed used Frying Oil Glycerolysis using Isopropyl Alcohol as a Reaction Solvent [PDF]

, 2012
An alkaline catalyzed glycerolysis of used frying oil using sodium hydroxide and isopropyl alcohol as solvent was investigated. A reaction kinetic model considering glycerol-triglyceride solubility and a second order kinetic mechanism was also developed.
Kumoro, A.C.
core  

Characterization of an extracellular lipase and its chaperone from Ralstonia eutropha H16 [PDF]

, 2012
Lipase enzymes catalyze the reversible hydrolysis of triacylglycerol to fatty acids and glycerol at the lipid–water interface. The metabolically versatile Ralstonia eutropha strain H16 is capable of utilizing various molecules containing long carbon ...
A Bajaj, A Pandey, A Roussel, AH Hobson, Anthony J. Sinskey, AR Macrae, B Joseph, BK Boekema, CF Budde, CF Budde, ChoKyun Rha, Christopher J. Brigham, CJ Brigham, DT Quyen, DT Quyen, E Lesuisse, E Severac, EJ Gilbert, EK Kim, F Rosenau, G Pouderoyen van, GF Mahler, GM York, H Park, H Treichel, HM Verheij, J Quandt, JD Schrag, JH Jeon, Jingnan Lu, JL Arpigny, JW Simons, KE Jaeger, KE Jaeger, KE Jaeger, KR Jegannathan, KS Ng, L Chong, L Fjerbaek, L Kanwar, LGJ Frenken, LGJ Frenken, LPG Franken, M El Khattabi, M Lotti, M Sanchez, MEM Noble, N Kulkarni, N Nawani, P Kahar, P Rathi, P Reis, P Skagerlind, R Gupta, R Rosenstein, R Simon, RG Kok, S Slater, SE Godtfredsen, SF Lin, SL Cherukuvada, SL Riedel, SP Singh, SS Kim, Y Bourne, Y Wang, YH Yang, ZS Derewenda   +67 more
core   +1 more source

Monoacylglycerol lipase – a target for drug development? [PDF]

British Journal of Pharmacology, 2012
The endocannabinoid (eCB) system is involved in processes as diverse as control of appetite, perception of pain and the limitation of cancer cell growth and invasion. The enzymes responsible for eCB breakdown are attractive pharmacological targets, and fatty acid amide hydrolase inhibitors, which potentiate the levels of the eCB anandamide, are now ...
openaire   +2 more sources

Targeting hepatic glycerolipid synthesis and turnover to treat fatty liver disease [PDF]

, 2014
Nonalcoholic fatty liver disease (NAFLD) encompasses a spectrum of metabolic abnormalities ranging from simple hepatic steatosis (accumulation of neutral lipid) to development of steatotic lesions, steatohepatitis, and cirrhosis.
Finck, Brian N, Schweitzer, George G
core   +3 more sources

Monoacylglycerol lipase: stopping surplus at the synapse

The Journal of Physiology, 2011
Endocannabinoids (eCBs) are a family of molecules derived from membrane phospholipids which exert biological effects through specific receptors. In the brain, eCBs are perhaps the most ubiquitous and potent neurotransmitters known to act in a retrograde manner.
Jaclyn I, Wamsteeker, Jaideep S, Bains
openaire   +3 more sources

Conformational gating, dynamics and allostery in human monoacylglycerol lipase [PDF]

Scientific Reports, 2020
AbstractInhibition of human Monoacylglycerol Lipase (hMGL) offers a novel approach for treating neurological diseases. The design of inhibitors, targeting active-inactive conformational transitions of the enzyme, can be aided by understanding the interplay between structure and dynamics.
Tyukhtenko, Sergiy, Ma, Xiaoyu, Rajarshi, Girija, Karageorgos, Ioannis, Anderson, Kyle W., Hudgens, Jeffrey W., Guo, Jason J., Nasr, Mahmoud L., Zvonok, Nikolai, Vemuri, Kiran, Wagner, Gerhard, Makriyannis, Alexandros   +11 more
openaire   +2 more sources

Exploring the Roles of Tuna‐Associated Acinetobacter sp. YFT067: Implications for Host Health and Metabolism

Animal Research and One Health, EarlyView.
This study firstly isolated a tuna‐derived gut probiotic Acinetobacter seifertii YFT067. Dietary administration of YFT067 played significant roles in promoting growth performance, SCFAs production, lipid absorption, and metabolism of the host, indicating YFT067 as a promising probiotic candidate for enhancing tuna aquaculture productivity through ...
Ying Zou, Hai Huang, Qiongyao Fu, Zhiyuan Lu, Zhiqiang Guo   +4 more
wiley   +1 more source

Gene Cloning, Characterization and Transesterification Reactions of Mgl-C255, a Lipolytic Enzyme from Neobacillus thermocopriae C255 Isolated from Ash from Popocatépetl Volcano

Macromol
Lipases and carboxylesterases are enzymes of biotechnological interest both for their reactions and their specificity. They have wide-ranging applications in the food, pharmaceuticals, biodiesel synthesis, and bioremediation industries.
Graciela Espinosa-Luna, Aaron S. Bustos-Baena, Rocio Solis-Palacios, Jonathan Lara-Sanchez, Aurelio Espinosa-Honorato, Rosa María Oliart-Ros   +5 more
doaj   +1 more source

Lactobacillus rhamnosus lowers zebrafish lipid content by changing gut microbiota and host transcription of genes involved in lipid metabolism. [PDF]

, 2015
The microbiome plays an important role in lipid metabolism but how the introduction of probiotic communities affects host lipid metabolism is poorly understood.
Carnevali, O, Cossignani, L, Falcinelli, S, Gioacchini, G, Maradonna, F, Merrifield, DL, Olivotto, I, Picchietti, S, Rodiles, A, Taddei, AR   +9 more
core   +2 more sources

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

British Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli, Emanuela Micioni Di Bonaventura, Giacomo Einaudi, Gustavo Provensi, Alessia Costa, Claudio D'Addario, Carlo Cifani, Maria Vittoria Micioni Di Bonaventura   +7 more
wiley   +1 more source