Results 41 to 50 of about 3,551 (187)

Reversible Monoacylglycerol Lipase Inhibitors: Discovery of a New Class of Benzylpiperidine Derivatives

Journal of Medicinal Chemistry, 2022
Monoacylglycerol lipase (MAGL) is the enzyme responsible for the metabolism of 2-arachidonoylglycerol in the brain and the hydrolysis of peripheral monoacylglycerols. Many studies demonstrated beneficial effects deriving from MAGL inhibition for neurodegenerative diseases, inflammatory pathologies, and cancer.
Giulia Bononi, Miriana Di Stefano, Giulio Poli, Gabriella Ortore, Philip Meier, Francesca Masetto, Isabella Caligiuri, Flavio Rizzolio, Marco Macchia, Andrea Chicca, Amir Avan, Elisa Giovannetti, Chiara Vagaggini, Annalaura Brai, Elena Dreassi, Massimo Valoti, Filippo Minutolo, Carlotta Granchi, Jürg Gertsch, Tiziano Tuccinardi   +19 more
openaire   +4 more sources

Design‐Driven Production of Soybean Oil‐Based Structured Fats as Potential Substitutes for Palm‐Based Fats

Journal of the American Oil Chemists' Society, EarlyView.
ABSTRACT This study examined whether enzymatic modification of soybean oil (SBO) can be tailored to produce trans‐free fats with physicochemical properties comparable to palm olein, stearin, or palm‐mid fractions (PMFs). US‐grown SBO was modified by lipase‐catalyzed acidolysis using palmitic acid at linearly interpolated substrate molar ratios (C16:0 ...
Ityotagher P. Aondoakaa, Silvana Martini, Casimir C. Akoh   +2 more
wiley   +1 more source

Biobased Polyurethane Films Based on Andiroba (Carapa guianensis) and Buriti (Mauritia flexuosa) Oil Polyols

Journal of Applied Polymer Science, EarlyView.
Polyurethane films were prepared from andiroba (Carapa guianensis) and buriti (Mauritia flexuosa) oil‐derived polyols, emphasizing their potential as bio‐based materials. UV–Vis analysis indicates the retention of carotenoid‐related chromophoric features within the polymer matrix.
João A. P. da Silva, Amanda L. Ferreira, Felipe F. C. Tavares, Chana M. da Silva, Cesar L. Petzhold, Nilo S. M. Cardozo   +5 more
wiley   +1 more source

Experimental and Modeling Studies of the Reaction Kinetics of Alkaline-Catalyzed used Frying Oil Glycerolysis using Isopropyl Alcohol as a Reaction Solvent [PDF]

, 2012
An alkaline catalyzed glycerolysis of used frying oil using sodium hydroxide and isopropyl alcohol as solvent was investigated. A reaction kinetic model considering glycerol-triglyceride solubility and a second order kinetic mechanism was also developed.
Kumoro, A.C.
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Seed storage oil mobilization is important but not essential for germination or seedling establishment in Arabidopsis [PDF]

, 2011
Triacylglycerol (TAG) is a major storage reserve in many plant seeds. We previously identified a TAG lipase mutant called sugar-dependent1 (sdp1) that is impaired in TAG hydrolysis following Arabidopsis (Arabidopsis thaliana) seed germination (Eastmond,
Eastmond, Peter J., Amélie A. Kelly, Eve Shaw, Peter J. Eastmond, Shaw, Eve, Quettier, Anne-Laure, Kelly, Amélie A., Anne-Laure Quettier   +7 more
core   +1 more source

Hydrolases & Lipases in GtoPdb v.2023.3

, 2023
Listed in this section are hydrolases not accumulated in other parts of the Concise Guide, such as monoacylglycerol lipase and acetylcholinesterase. Pancreatic lipase is the predominant mechanism of fat digestion in the alimentary system; its inhibition ...
Fairlie, David, Fowler, Christopher J., Doherty, Patrick, Southan, Christopher, Rawlings, Neil, Alexander, Stephen P.H., Turner, Anthony J., Overall, Christopher M.   +7 more
core   +1 more source

Exploring the Roles of Tuna‐Associated Acinetobacter sp. YFT067: Implications for Host Health and Metabolism

Animal Research and One Health, EarlyView.
This study firstly isolated a tuna‐derived gut probiotic Acinetobacter seifertii YFT067. Dietary administration of YFT067 played significant roles in promoting growth performance, SCFAs production, lipid absorption, and metabolism of the host, indicating YFT067 as a promising probiotic candidate for enhancing tuna aquaculture productivity through ...
Ying Zou, Hai Huang, Qiongyao Fu, Zhiyuan Lu, Zhiqiang Guo   +4 more
wiley   +1 more source

Gene Cloning, Characterization and Transesterification Reactions of Mgl-C255, a Lipolytic Enzyme from Neobacillus thermocopriae C255 Isolated from Ash from Popocatépetl Volcano

Macromol
Lipases and carboxylesterases are enzymes of biotechnological interest both for their reactions and their specificity. They have wide-ranging applications in the food, pharmaceuticals, biodiesel synthesis, and bioremediation industries.
Graciela Espinosa-Luna, Aaron S. Bustos-Baena, Rocio Solis-Palacios, Jonathan Lara-Sanchez, Aurelio Espinosa-Honorato, Rosa María Oliart-Ros   +5 more
doaj   +1 more source

Direct Chiral Supercritical Fluid Chromatography–Mass Spectrometry Analysis of Monoacylglycerol and Diacylglycerol Isomers for the Study of Lipase-Catalyzed Hydrolysis of Triacylglycerols

, 2023
The fast and selective separation method of intact monoacylglycerol (MG) and diacylglycerol (DG) isomers using chiral supercritical fluid chromatography–mass spectrometry (SFC–MS) was developed and employed to study lipase selectivity in the hydrolysis ...
Sára Rademacherová (14768775), Eliška Prchalová (14768781), Rudolf Andrýs (10844422), Dávid Maliňák (14768778), Miroslav Lísa (1564087), Oleksandr Kozlov (14768769), Eliška Horáková (14768772)   +6 more
core   +1 more source

Obtenção de ésteres alquílicos (Biodiesel) por via enzimática a partir do óleo de soja [PDF]

, 2002
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas. Programa de Pós-Graduação em Química.A busca por fontes alternativas de energia tem sido tema de interesse em diversos setores da sociedade e da ...
Costa Neto, Pedro Ramos da
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