Results 21 to 30 of about 5,459 (175)

Label-free measurement of the yeast short chain TAG lipase activity by ESI-MS after one-step esterification

Journal of Lipid Research, 2017
Triacylglycerol (TAG) lipases hydrolyze ester bonds in TAG and release diacylglycerol (DAG), monoacylglycerol (MAG), and FA. We present a one-step chemical derivatization method for label-free quantification of a mixture of TAG, DAG, and MAG following ...
Hye Jin Ham, Jongcheol Seo, Hye-Joo Yoon, Seung Koo Shin   +3 more
doaj   +1 more source

Monoacylglycerol Lipase Regulates Fever Response

PLOS ONE, 2015
Cyclooxygenase inhibitors such as ibuprofen have been used for decades to control fever through reducing the levels of the pyrogenic lipid transmitter prostaglandin E2 (PGE2). Historically, phospholipases have been considered to be the primary generator of the arachidonic acid (AA) precursor pool for generating PGE2 and other eicosanoids.
Manuel Sanchez-Alavez, William Nguyen, Simone Mori, Gianluca Moroncini, Andreu Viader, Daniel K Nomura, Benjamin F Cravatt, Bruno Conti   +7 more
openaire   +4 more sources

Production of a biodiesel-like biofuel without glycerol generation, by using Novozym 435, an immobilized lipase [PDF]

, 2014
Background: Novozym 435, a commercial lipase from Candida antarctica, recombinant, expressed in Aspergillus niger, immobilized on macroporous acrylic resin, has been already described in the obtention of biodiesel.
Bautista, F.M., Calero, Juan, Luna, Carlos, Luna, Diego, Posadillo, Alejandro, Romero, Antonio A., Sancho, Enrique D., Verdugo-Escamilla, Cristóbal   +7 more
core   +3 more sources

Simplified assays of lipolysis enzymes for drug discovery and specificity assessment of known inhibitors

Journal of Lipid Research, 2016
Lipids are used as cellular building blocks and condensed energy stores and also act as signaling molecules. The glycerolipid/ fatty acid cycle, encompassing lipolysis and lipogenesis, generates many lipid signals.
Jose Iglesias, Julien Lamontagne, Heidi Erb, Sari Gezzar, Shangang Zhao, Erik Joly, Vouy Linh Truong, Kathryn Skorey, Sheldon Crane, S.R.Murthy Madiraju, Marc Prentki   +10 more
doaj   +1 more source

Hydrolysis of coconut oil (Cocos nucífera L.) by specificity and no positional specificity enzimes.

Grasas y Aceites, 1997
The characteristic fatty acid composition of coconut oil provides mainly short- and medium- chain fatty acids when incorporated to the diet. These fatty acids have nutritional advantages because their metabolic disposition allows the rapid obtention of ...
R. Rodríguez, J. Sanhueza, A. Valenzuela, S. Nieto   +3 more
doaj   +1 more source

Glicerolisis de aceite de sardina catalizada por una lipasa dependiente de agua en diferentes tert-alcoholes como medio de reacción [PDF]

, 2015
The production of monoacylglycerol rich in polyunsaturated fatty acids (PUFA) via enzymatic glycerolysis of sardine oil in a homogeneous system was evaluated. Reactions were conducted in two different tert-alcohols. Based on the phase equilibrium data,
Beltrán Calvo, Sagrario, Bucio López, Silvia Liliana, García Solaesa, Ángela, Melgosa Gómez, Rodrigo, Sanz Díez, Mª Teresa   +4 more
core   +3 more sources

Arachis hypogaea monoacylglycerol lipase AhMAGL3b participates in lipid metabolism. [PDF]

BMC Plant Biol
Monoacylglycerol lipase (MAGL) belongs to the serine hydrolase family; it catalyzes MAG to produce glycerol and free fatty acids (FFAs), which is the final step in triacylglycerol (TAG) hydrolysis. The effects of MAGL on comprehensive lipid metabolism and plant growth and development have not been elucidated, especially in Arachis hypogaea, an ...
Zhan Y, Wang J, Zhao X, Zheng Z, Gan Y.
europepmc   +4 more sources

Storage oil hydrolysis during early seedling growth [PDF]

, 2009
Storage oil breakdown plays an important role in the life cycle of many plants by providing the carbon skeletons that support seedling growth immediately following germination.
Andrews, Anne-Laure Quettier, Athenstaedt, Athenstaedt, Baker, Beisson, Chia, Ducharme, Eastmond, Eastmond, Eastmond, El-Kouhen, Fernandez, Frandsen, Fuchs, Fuchs, Ghosh, Ghosh, Graham, Grönke, Gupta, Hayashi, Hellyer, Hills, Hills, Hills, Huang, Ishiguro, Jennens, Jolivet, Kurat, Lass, Lin, Lin, Maeshima, Matsui, May, Mhaske, Mukherjee, Murphy, Murphy, Ncube, Noll, Ohlrogge, Ollis, Peter J. Eastmond, Poxleitner, Quettier, Robenek, Rydel, Schweiger, Siloto, Somerville, Stahl, Ubersax, Wanner, Zimmermann   +56 more
core   +1 more source

Monoacylglycerol-enriched oil increases EPA/DHA delivery to circulatory system in humans with induced lipid malabsorption conditions1

Journal of Lipid Research, 2016
It was hypothesized that under induced lipid malabsorption/maldigestion conditions, an enriched sn-1(3)-monoacylglycerol (MAG) oil may be a better carrier for n-3 long-chain PUFAs (LC-PUFAs) compared with triacylglycerol (TAG) from fish oil.
Cristina Cruz-Hernandez, Frédéric Destaillats, Sagar K. Thakkar, Laurence Goulet, Emma Wynn, Dominik Grathwohl, Claudia Roessle, Sara de Giorgi, Luc Tappy, Francesca Giuffrida, Vittorio Giusti   +10 more
doaj   +1 more source

Biochemical and pharmacological characterization of human α/β-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12)

Journal of Lipid Research, 2012
In the central nervous system, three enzymes belonging to the serine hydrolase family are thought to regulate the life time of the endocannabinoid 2-arachidonoylglycerol (C20:4) (2-AG). From these, monoacylglycerol lipase (MAGL) is well characterized and,
Dina Navia-Paldanius, Juha R. Savinainen, Jarmo T. Laitinen   +2 more
doaj   +1 more source