Results 41 to 50 of about 5,459 (175)

Monoacylglycerol lipase – a target for drug development? [PDF]

British Journal of Pharmacology, 2012
The endocannabinoid (eCB) system is involved in processes as diverse as control of appetite, perception of pain and the limitation of cancer cell growth and invasion. The enzymes responsible for eCB breakdown are attractive pharmacological targets, and fatty acid amide hydrolase inhibitors, which potentiate the levels of the eCB anandamide, are now ...
openaire   +2 more sources

Micro and Nanoencapsulation of Omega‐3 Fatty Acids: Functional Applications and Future Perspectives in Food Systems

Food Safety and Health, EarlyView.
Whey protein‐based microencapsulation for omega‐3 PUFA delivery in food systems. Objective: Enhance oxidative stability & bioavailability of omega‐3 PUFAs using whey protein as an encapsulating agent. Current methods: Spray drying & coacervation—effective but limited by heat sensitivity and encapsulation efficiency. Emerging technologies: Electrospray &
Jihan M. Kassem, Fadwa W. Abdulqahar, Ahmed A. Zaky, Mohamed Said Boulkrane, Aya Darwish, Amr Farouk, Beraat Ozçelik, Osama Magouz, Xueming Liu, Tamer M. El‐Messery   +9 more
wiley   +1 more source

Experimental and Modeling Studies of the Reaction Kinetics of Alkaline-Catalyzed used Frying Oil Glycerolysis using Isopropyl Alcohol as a Reaction Solvent [PDF]

, 2012
An alkaline catalyzed glycerolysis of used frying oil using sodium hydroxide and isopropyl alcohol as solvent was investigated. A reaction kinetic model considering glycerol-triglyceride solubility and a second order kinetic mechanism was also developed.
Kumoro, A.C.
core  

Wide-gene expression analysis of lipid-relevant genes in nutritionally challenged gilthead sea bream (Sparus aurata) [PDF]

, 2017
Disturbances of lipid metabolism are a major problem in livestock fish and the present study analysed the different tissue expression patterns and regulations of 40 lipid-relevant genes in gilthead sea bream.
Ballester-Lozano, Gabriel F., Benedito-Palos, Laura, Pérez-Sánchez, Jaume   +2 more
core   +1 more source

Monoacylglycerol lipase: stopping surplus at the synapse

The Journal of Physiology, 2011
Endocannabinoids (eCBs) are a family of molecules derived from membrane phospholipids which exert biological effects through specific receptors. In the brain, eCBs are perhaps the most ubiquitous and potent neurotransmitters known to act in a retrograde manner.
Jaclyn I, Wamsteeker, Jaideep S, Bains
openaire   +3 more sources

Conformational gating, dynamics and allostery in human monoacylglycerol lipase [PDF]

Scientific Reports, 2020
AbstractInhibition of human Monoacylglycerol Lipase (hMGL) offers a novel approach for treating neurological diseases. The design of inhibitors, targeting active-inactive conformational transitions of the enzyme, can be aided by understanding the interplay between structure and dynamics.
Tyukhtenko, Sergiy, Ma, Xiaoyu, Rajarshi, Girija, Karageorgos, Ioannis, Anderson, Kyle W., Hudgens, Jeffrey W., Guo, Jason J., Nasr, Mahmoud L., Zvonok, Nikolai, Vemuri, Kiran, Wagner, Gerhard, Makriyannis, Alexandros   +11 more
openaire   +2 more sources

Efficacy of omega‐3 fatty acids as a functional food: a multifaceted approach to health reinforcement

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Omega‐3 fatty acids (omega‐3s) are polyunsaturated fatty acids linked with numerous health benefits. Omega‐3s exhibit multifaceted activities through various mechanisms. Eicosapentaenoic acid (EPA) alleviates oxidative stress by lowering reactive oxygen species and improving oxidative stress in brain tissues and acts against neurodegenerative ...
Md Faruque Ahmad, Abdulrahman A Alsayegh, Anjum Khanam, Awais Ahmed, António Raposo, Farkad Bantun, Md Zeyaullah, Ahmad O Babalghith, Abdullah F Aldairi, Boshra Mozaffar, Mohammed F Bajahzer, Mohamed H Abdelrahman, Mohammad Intakhab Alam   +12 more
wiley   +1 more source

Gene Cloning, Characterization and Transesterification Reactions of Mgl-C255, a Lipolytic Enzyme from Neobacillus thermocopriae C255 Isolated from Ash from Popocatépetl Volcano

Macromol
Lipases and carboxylesterases are enzymes of biotechnological interest both for their reactions and their specificity. They have wide-ranging applications in the food, pharmaceuticals, biodiesel synthesis, and bioremediation industries.
Graciela Espinosa-Luna, Aaron S. Bustos-Baena, Rocio Solis-Palacios, Jonathan Lara-Sanchez, Aurelio Espinosa-Honorato, Rosa María Oliart-Ros   +5 more
doaj   +1 more source

Endocannabinoid system gene expression in mesocorticolimbic brain regions of individuals with alcohol use disorder: A descriptive study

Addiction, EarlyView.
Abstract Aims To describe differences in the expression of genes encoding cannabinoid receptors (CNR1, CNR2), the associated receptor GRP55 and the enzymes fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MGLL) between individuals with alcohol use disorder (AUD) and controls in key mesocorticolimbic brain regions.
María Salud García‐Gutiérrez, Abraham Bailén Torregrosa, Francisco Navarrete, Auxiliadora Aracil‐Fernández, Gabriel Rubio, Jorge Manzanares   +5 more
wiley   +1 more source

Improved production of a recombinant lipase expressed in and its application for conversion of microalgae oil to biodiesel [PDF]

, 2013
Part 2: Trust and PrivacyInternational audienceTrust and privacy have been widely studied as key issues and success factors for e-commerce. The advent of m-commerce calls for revisiting these concepts and re-examining their antecedents in the mobile ...
Jinjin Huang, Ji Xia, Zhen Yang, Feifei Guan, Di Cui, Guohua Guan, Wei Jiang, Ying Li   +7 more
core   +2 more sources