Results 101 to 110 of about 85,545 (297)
Neurogenic Stuttering and Lateralized Motor Deficits Induced by Tranylcypromine
A case of neurogenic stuttering induced by the monoamine oxidase inhibitor tranylcypromine is described. The association of neurogenic stuttering with acquired lateralized motor deficits in the patient described is discussed with reference to current ...
J. D. Duffy
doaj +1 more source
Castration resistant prostate cancer patients treated with enzalutamide may develop resistance to the drug. Here, the authors report that monoamine oxidase-A expression is increased in these resistant tumors and that the antidepressants phenelzine ...
Keliang Wang +14 more
doaj +1 more source
Drugs Affecting 5-HT Systems [PDF]
Seminar transcriptIt was in the very early hours of a February morning in 1977 that I first looked down the microscope and saw yellow fluorescence, characteristic of 5-hydroxytryptamine (5-HT) in frozen sections of Octopus brain. After struggling for two
Overy, C, Tansey, EM
core
Assessment of the direct and indirect effects of MPP+ and dopamine on the human proteasome: implications for Parkinson's disease aetiology [PDF]
Mitochondrial impairment, glutathione depletion and oxidative stress have been implicated in the pathogenesis of Parkinson’s disease (PD), linked recently to proteasomal dysfunction.
Beck, KE +5 more
core +1 more source
Abstract Background & Aims There are few effective treatments for methamphetamine use disorder, despite increasing global demand. Here, we assessed the safety and feasibility of outpatient psilocybin‐assisted psychotherapy for methamphetamine use disorder. Design Single arm, open label pilot study.
Elizabeth Knock +8 more
wiley +1 more source
Non-nicotine constituents in cigarette smoke extract enhance nicotine addiction through monoamine oxidase A inhibition [PDF]
Guanglin Liu +12 more
openalex +1 more source
Stroke induces mitochondrial dysfunction and motor disorders. FES combined with physical exercises can help restore mitochondrial function by regulating the formation of reactive oxygen species and, consequently, contributing to functional recovery. ABSTRACT Background Stroke is commonly accompanied by motor disorders secondary to the initial injury ...
A. Larrea +5 more
wiley +1 more source
Twenty-six novel thiosemicarbazone derivative B1–B26 were synthesized via condensation reactions between the corresponding thiosemicarbazides and aldehydes.
Betül Kaya Çavuşoğlu +7 more
doaj +1 more source
MPTP-induced degeneration: interference with glutamatergic toxicity [PDF]
Parkinson's disease (PD) is characterised by the progressive degeneration of nigrostriatal dopamine (DA) neurons resulting in the major symptoms of akinesia and rigidity.
Lange, Klaus W. +3 more
core
Preclinical models for evaluating psychedelics in the treatment of major depressive disorder
Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander +5 more
wiley +1 more source

