Results 101 to 110 of about 45,533 (284)
Raised endogenous monoamine oxidase inhibitor output in postwithdrawal alcoholics: effects of L-dopa and ethanol. [PDF]
, 1982 Urinary output of endogenous monoamine oxidase inhibitor was significantly greater in a group of postwithdrawal alcoholics than in controls. An oral dose of 0.5 g of L-dopa reduced output to control values in the alcoholics, but in the controls ...
Bhattacharya, S.K. +6 more
core
Addiction, EarlyView.Abstract Background & Aims There are few effective treatments for methamphetamine use disorder, despite increasing global demand. Here, we assessed the safety and feasibility of outpatient psilocybin‐assisted psychotherapy for methamphetamine use disorder. Design Single arm, open label pilot study.
Elizabeth Knock +8 more
wiley +1 more source
Serotonin Degradation and Lipid Metabolism Regulate Human Tc2 Cell Effector Functions
Allergy, EarlyView.Human Tc2 cells exhibit a metabolically active phenotype characterized by enhanced glycolysis, mitochondrial respiration, and fatty acid uptake dependent on PPARγ. Alarmins strongly amplify IL‐5 and IL‐13 production in Tc2 cells, supporting a shared immunometabolic program across type 2 lymphocytes.
Sabrina de Souza Ferreira +13 more
wiley +1 more source
Platelet monoamine oxidase: specific activity and turnover number in headache [PDF]
, 1982 Monoamine oxidase turnover numbers (molecules of substrate converted to product per minute per active site) have been calculated for the human platelet enzyme using [H]pargyline.
Brown, O. K. +7 more
core +1 more source
Studies on Monoamine Oxidase (Report XXIV) Effect of Harmine on Monoamine Oxidase
Japanese Journal of Pharmacology, 1974 Abstract Using beef brain and liver mitochondria, the effects of several inhibitors on the oxidation of serotonin and tyramine were studied. Mitochondrial MAO of beef brain showed pH optima of 8.8 with serotonin and 8.0 with tyramine. Pheniprazine had similar effects on the oxidations of serotonin and tyramine by brain MAO at pH 7.4 and pH 8.5 ...
openaire +3 more sources
Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?
British Journal of Pharmacology, EarlyView.Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli +7 more
wiley +1 more source
Secondary structure of monoamine oxidase by FTIR spectroscopy. [PDF]
, 1995 The secondary structure of human monoamine oxidase A and bovine monoamine oxidase B has been investigated by Fourier Transform Attenuated Total Reflection Spectroscopy (FTIR ATR). The experimental results are compared for both isoenzymes and the data are
Ramsay, R +13 more
core +1 more source
Physiological Reports, 2019 Serotonin (5‐HT) accumulates in the heart during myocardial ischemia and induces deleterious effects on the cardiomyocytes through receptor‐dependent and monoamine oxidase‐dependent pathways.
Takashi Sonobe +3 more
doaj +1 more source
Cancer pain: current practice and emerging targets
British Journal of Pharmacology, EarlyView.Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye +5 more
wiley +1 more source
Monoamine oxidase activities in tissues of thiamine-deficient rats [PDF]
, 1969 The oxidation of monoamine by homogenates of tissues of thiamine-deficient rats was measured with noradrenaline as substrate. Monoamine oxidase activities were depressed in tissues in which the catecholamine content had previously been found raised ...
H Iwata, T Nishikawa, S Fujimoto
core +1 more source