Results 131 to 140 of about 36,956 (236)

Comparative Sleep Architecture Profiles of Antidepressants in Mice: Pharmacological Characterization of Paroxetine, Sertraline, Duloxetine, Mirtazapine and Vortioxetine

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
This study compared five antidepressants (paroxetine, sertraline, duloxetine, mirtazapine, and vortioxetine) in mice using EEG/EMG, revealing distinct effects on REM and NREM sleep. The figure illustrates changes in sleep architecture during the light phase (ZT0–12).
Junya Maruoka, Ryo Egami, Yuto Akita, Kohei Kozuka, Yusuke Kakumoto, Tetsuro Kikuchi, Kazuhiko Kume   +6 more
wiley   +1 more source

Monoamine Oxidase Inhibitors in Drug Discovery Against Parkinson's Disease: An Update. [PDF]

Pharmaceuticals (Basel)
Ribeiro LV, Massuda LE, Gontijo VS, Viegas C.   +3 more
europepmc   +1 more source

Investigating the Phytochemical Constituents, Anti‐Inflammatory, and Neuropharmacological Activities of Podocarpus neriifolius Leaves Through FT‐IR, GC–MS, Experimental Studies, Molecular Docking, and Molecular Dynamics Simulations

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT Podocarpus neriifolius, a widely distributed medicinal plant in South and Southeast Asia, has traditionally been used to treat rheumatism and joint pain. This study aimed to investigate the phytochemical profile and therapeutic potential of the ethanolic leaf extract of P.
Neamul Hoque, Md. Tashrif Rahman Tipu, Md Abul Bashar, Raju Dash, Kutub Uddin Ahamed, Md. Liakot Ali, Md. Jahirul Islam Mamun, Bakul Akter, Mohammed Kamrul Hossain, Nawreen Monir Proma   +9 more
wiley   +1 more source

Synthesis and biological evaluation of <i>N</i>/<i>O</i>-propargylated diarylpyrimidines as dual inhibitors of acetylcholinesterase and monoamine oxidase. [PDF]

RSC Adv
Kumar N, Jangid K, Kumar V, Dwivedi AR, Kumar V, Devi B, Arora T, Parkash J, Kumar V.   +8 more
europepmc   +1 more source

The Use of Statins in Parkinson's and Alzheimer's Disease: A 2021–2025 State‐of‐the‐Art Review of Clinical and Preclinical Evidence

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT Statins, widely prescribed for cardiovascular prevention, have emerged as potential disease‐modifying agents in neurodegenerative disorders due to their pleiotropic effects on cholesterol metabolism, neuroinflammation, oxidative stress, and protein aggregation.
Luigi Maria Chiatto, Lucia Buccarello, Giuseppe Carota, Rocco Salvatore Calabrò, Carmela Rifici, Emanuela Esposito, Alessio Ardizzone, Giuseppe Caruso   +7 more
wiley   +1 more source

Dual Inhibitors of Acetylcholinesterase and Monoamine Oxidase-B for the Treatment of Alzheimer's Disease. [PDF]

Molecules
Asim A, Jastrzębski MK, Kaczor AA.
europepmc   +1 more source

Correction to "Monoamine Oxidase-A Is a Novel Driver of Stress-Induced Premature Senescence Through Inhibition of Parkin-Mediated Mitophagy". [PDF]

Aging Cell
europepmc   +1 more source

Evolutionary and Functional Analysis of Monoamine Oxidase F: A Novel Member of the Monoamine Oxidase Gene Family. [PDF]

Genome Biol Evol
Merello Oyarzún G, Olivares-Costa M, Basile L, Pástor TP, Mendoza-Soto P, Padilla-Santiago L, Mardones GA, Binda C, Opazo JC.   +8 more
europepmc   +1 more source

Enhancing Dopamine Accumulation in Secretory Vesicles of PC12 Cells: Mechanisms, Applications and Limitations

Journal of Neurochemistry, Volume 170, Issue 6, June 2026.
Schematic representation of a large dense‐core vesicle in PC12 cells highlighting its main molecular organization. The diagram illustrates the presence of membrane transporters, proton pumps and intravesicular matrix proteins that establish the electrochemical gradients required for neurotransmitter uptake, vesicle acidification and efficient storage ...
Noemi Socas‐Pérez, Ricado Borges, José David Machado   +2 more
wiley   +1 more source

Integrated New Approach Methodologies Reveal the Potential Role of 2,7-Dibromocarbazole in Parkinson's Disease via Monoamine Oxidase B Inhibition and Dopaminergic Dysfunction. [PDF]

Environ Sci Technol
Lu X, Luo Y, Peng P, Xing X, Xia W, Yin H, Li H, Xu S.   +7 more
europepmc   +1 more source