Results 61 to 70 of about 186,317 (243)

MAO inhibitors for treatment-resistant depression: Bringing an updated perspective on pioneering drugs

open access: yesPharmacological Research
In the 1950s, monoamine oxidase inhibitors transformed the pharmacological treatment of mental disorders as the first class of antidepressant drugs.
Larissa Junkes   +4 more
doaj   +1 more source

Selegilin Exerts Antidepressant-Like Effects During the Forced Swim Test in Adrenocorticotropic Hormone–Treated Rats

open access: yesJournal of Pharmacological Sciences, 2008
In the present study, we investigated the effect of adrenocorticotropic hormone (ACTH) on the immobilization of rats in the forced swim test after the administration of selegiline, a selective and irreversible monoamine oxidase (MAO)-B inhibitor.
Yoshihisa Kitamura   +7 more
doaj   +1 more source

Psilocybin‐assisted psychotherapy for methamphetamine use disorder: A pilot open‐label safety and feasibility study

open access: yesAddiction, EarlyView.
Abstract Background & Aims There are few effective treatments for methamphetamine use disorder, despite increasing global demand. Here, we assessed the safety and feasibility of outpatient psilocybin‐assisted psychotherapy for methamphetamine use disorder. Design Single arm, open label pilot study.
Elizabeth Knock   +8 more
wiley   +1 more source

Neuroprotection by dopamine agonists [PDF]

open access: yes, 1994
Research on Parkinson's disease has led to new hypotheses concerning the mechanisms of neurodegeneration and to the development of neuroprotective agents.
Rausch, W. D.   +5 more
core   +1 more source

Small molecule probes for the specific imaging of monoamine oxidase A and monoamine oxidase B

open access: yesiRADIOLOGY
Monoamine oxidases (MAOs) are a class of flavin enzymes that are mainly present in the outer membrane of mitochondria and play a crucial role in maintaining the homeostasis of monoamine neurotransmitters in the central nervous system.
Yi Fang, Zhengping Chen, Min Yang
doaj   +1 more source

Synthesis of certain nitropyridine derivatives bearing 2-thiazolyl hydrazines with expected monoamine oxidase inhibitory activity [PDF]

open access: yesBulletin of Pharmaceutical Sciences. Assiut University, 1999
Two series of nitropyridine derivs. bearing 2-​thiazolyl hydrazines were synthesized and evaluated for their monoamine oxidase (MAO) inhibitory activity by in vitro tests to assay their effect on rat liver mitochondria by a kynuramine fluorimetric assay.
Hoda Hassan
doaj   +1 more source

Serotonin Degradation and Lipid Metabolism Regulate Human Tc2 Cell Effector Functions

open access: yesAllergy, EarlyView.
Human Tc2 cells exhibit a metabolically active phenotype characterized by enhanced glycolysis, mitochondrial respiration, and fatty acid uptake dependent on PPARγ. Alarmins strongly amplify IL‐5 and IL‐13 production in Tc2 cells, supporting a shared immunometabolic program across type 2 lymphocytes.
Sabrina de Souza Ferreira   +13 more
wiley   +1 more source

The Impact of Common Medications on Male Fertility: An Updated Systematic Review

open access: yesAndrology, EarlyView.
ABSTRACT Background Compared with those of cytotoxic treatments, the potential effects of common medications on the fertility of men trying to conceive currently or planning to conceive in the future are less well described. The use of common medications may modify the gonadotropic axis, spermatogenesis, and epididymal maturation or alter male ...
Lina Jebli   +7 more
wiley   +1 more source

Interaction between histamine and monoamine oxidase inhibitors

open access: yes, 1969
The monoamine oxidase inhibitors tranylcypromine, nialamide and iproniazid potentiated the actions of histamine on the blood pressure of the cat and on the tracheo-bronchial muscle of the guinea-pig.
G S Allen, M J Rand
core   +1 more source

Evaluation of oxidative stress in brucella infected cows [PDF]

open access: yesJournal of Stress Physiology & Biochemistry, 2010
Oxidative stress can influence the metabolism of cells in vital organs of the body. Oxidative stress is extremely dangerous as it does not exhibit any symptom and is recognisable with great difficulty by means of laboratory methods.
N. Kataria   +3 more
doaj  

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