Results 51 to 60 of about 36,956 (236)

High‐Fat Diet Exacerbates Neuropathology in a Transgenic Mouse Model of Multiple System Atrophy

Movement Disorders, EarlyView.
Abstract Background Multiple system atrophy (MSA) is a rare and devastating neurodegenerative disorder. Accumulating clinical and preclinical evidence suggests that diabetes and insulin resistance may adversely influence MSA pathophysiology. Objective We investigated the potential association between diabetes, impaired glucose homeostasis, and MSA ...
Marie‐Laure Arotcarena, Anna Delamarre, Miguel Lopez‐Cuina, Hugo Martin, Elio Balpe, Xavier Fioramonti, Erwan Bezard, Wassilios G. Meissner   +7 more
wiley   +1 more source

Small molecule probes for the specific imaging of monoamine oxidase A and monoamine oxidase B

iRADIOLOGY
Monoamine oxidases (MAOs) are a class of flavin enzymes that are mainly present in the outer membrane of mitochondria and play a crucial role in maintaining the homeostasis of monoamine neurotransmitters in the central nervous system.
Yi Fang, Zhengping Chen, Min Yang
doaj   +1 more source

Investigation of the Mechanism of Cinnamaldehyde in Irritable Bowel Syndrome Based via Network Pharmacology, Molecular Docking, and Animal Experiments

Pediatric Discovery, EarlyView.
Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu, Boqing Xu, Chunfang Dai, Yayan Pang, Zhifang Dong   +4 more
wiley   +1 more source

Activity of an oleanane-type tritrepenoid saponin from A. glycyphyllos on human recombinant MAO enzymes [PDF]

Pharmacia
For centuries, plants have been a leading point in the identification of potential therapeutic agents. Monoamine oxidase inhibition is a key mechanism in the treatment of various neurological and psychiatric diseases.
Aleksandar Shkondrov, Magdalena Kondeva-Burdina, Ivan Stambolov, Ilina Krasteva   +3 more
doaj   +3 more sources

Efficacy and safety of traditional Chinese medicine aromatherapy for insomnia patients with predominant difficulty in sleep initiation

Sleep Research, EarlyView.
Abstract Background Insomnia is highly prevalent, and non‐pharmacological strategies to facilitate sleep initiation remain an important clinical priority. Aims This study aimed to evaluate the tolerability, safety, and preliminary sleep‐related effects of a herbal aromatherapy liquid administered using a Traditional Chinese Medicine Aromatherapy Sleep ...
Huafeng Shan, Chun Wang, Dengyi Cao, Yi Long, Xiaowei Huang, Jiayang Meng, Zhongxia Shen, Xiaomei Zhang, Qinjuan Ren   +8 more
wiley   +1 more source

Evaluation of oxidative stress in brucella infected cows [PDF]

Journal of Stress Physiology & Biochemistry, 2010
Oxidative stress can influence the metabolism of cells in vital organs of the body. Oxidative stress is extremely dangerous as it does not exhibit any symptom and is recognisable with great difficulty by means of laboratory methods.
N. Kataria, A.K Kataria, R. Maan, A.K. Gahlot   +3 more
doaj  

Unraveling the Physicochemical Landscape of Organoselenium Compounds in Nanocarrier Systems

The Chemical Record, EarlyView.
Main nanocarriers employed to enhance the bioavailability and transport of organoselenium compounds. The image illustrates the key interaction forces that stabilize these organoselenium species in solution, enabling their application in drug delivery systems, catalysis, photoelectronic devices, and sensing technologies. In recent years, publications on
Romelly Eugenia Rojas Ramírez, Tielle Moraes de Almeida, Daiani Canabarro Leite, Gilson Zeni   +3 more
wiley   +1 more source

Correlation of serum IgE with stress in Indian dromedaries affected with skin wounds [PDF]

Journal of Stress Physiology & Biochemistry, 2010
The present investigation was planned to explore stress induced changes in the levels of IgE by correlating them with the important parameters of stress like cortisol and free radical scavengers in the serum of Indian dromedaries.
A.K Kataria, N. Kataria, R. Maan
doaj  

Deprenyl in Tourette’s Syndrome and ADHD

Pediatric Neurology Briefs, 1996
The efficacy of deprenyl, a monoamine oxidase inhibitor, was evaluated in the treatment of ADHD in 24 children and adolescents with comorbid Tourette’s syndrome (TS) enrolled at the University of Rochester and Baylor College of Medicine.
J Gordon Millichap
doaj   +1 more source

Dopamine: The Essential Bridge Mediating Obstructive Sleep Apnea and Hippocampus‐Dependent Learning and Memory Impairments

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Obstructive sleep apnea is a clinical syndrome that triggers a series of pathophysiologic changes, including disturbed sleep architecture, chronic intermittent hypoxia and hypercapnia, and ultimately severe cognitive dysfunction. The hippocampus plays a key role in various cognitive processes such as learning and memory.
Rui Fan, Tao Li, Yan Yan
wiley   +1 more source