Results 51 to 60 of about 45,533 (284)

Interaction between phenylpropanolamine and monoamine oxidase inhibitors [PDF]

open access: yes, 1969
The role of monoamine oxidase in the potentiation of the pressor effect of phenylpropanolamine (norephedrine) by monoamine oxidase inhibitors has been investigated.
A D’Mello
core   +1 more source

Behavioral and Biochemical Effects of Monosodium Glutamate on Weaned Male Rats [PDF]

open access: yesVeterinary Medical Journal - Giza, 2014
The present study investigates the effect of long term treatment (0.06,0.3 and 0.6g/kg b. wt., orally) with monosodium glutamate (MSG) on open field test and some biochemical parameters such as cortisol, serotonin (5-HT) and monoamine oxidase activity ...
Mervat Kamel   +3 more
doaj   +1 more source

Multimodal Imaging Reveals Rapid Catecholamine Uptake and Release by Neutrophils

open access: yesAdvanced Science, EarlyView.
We show that immune cells (neutrophils) synthesize, uptake, and store catecholamine neurotransmitters such as dopamine or adrenaline. They also release them in response to specific stimuli (serotonin), which we directly visualize using fluorescent nanosensors. We further demonstrate that catecholamines affect neutrophil functions (NETosis) and platelet
Jennifer Mohr   +19 more
wiley   +1 more source

Neuroprotection by dopamine agonists [PDF]

open access: yes, 1994
Research on Parkinson's disease has led to new hypotheses concerning the mechanisms of neurodegeneration and to the development of neuroprotective agents.
Rausch, W. D.   +5 more
core   +1 more source

Long-term low-dose oxytetracycline potentially leads to neurobehavioural changes

open access: yesEcotoxicology and Environmental Safety, 2021
Trace levels of oxytetracycline (OTC)—a veterinary antibiotic and feed additive—are widespread in the environment. Studies revealed that OTC potentially impairs thyroid function, which may affect neurobehaviour; however, the impact of exposure to ...
Yushu Qiu   +8 more
doaj   +1 more source

Hypothalamic Control of Liver Health and Disease: From Circuits to Pathophysiology and Therapies

open access: yesAdvanced Science, EarlyView.
This review delineates the hypothalamic circuits that control liver homeostasis via autonomic and neuroendocrine pathways. Dysregulation of this hypothalamus–liver axis drives disease progression across a spectrum including steatotic liver disease, liver inflammation and injury, fibrosis, cirrhosis, and hepatocellular carcinoma.
Qin Tang   +7 more
wiley   +1 more source

Synthesis and in vitro evaluation of pteridine analogues as monoamine oxidase B and nitric oxice synthase inhibitors [PDF]

open access: yes, 2009
Monoamine oxidase B (MAO-B) and nitric oxide synthase (NOS) have both been implicated in the pathology of neurodegenerative diseases. In an attempt to design dual-target-directed drugs that inhibit both these enzymes, a series of pteridine-2,4-dione ...
Petzer, Jacobus P.   +5 more
core   +1 more source

Intranasal Delivery of Gallium–Quercetin Nanoparticles for Multi‐Target Ferroptosis Inhibition in Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
Leveraging the chemical similarity between Ga3+ and Fe3+ as well as the antioxidant properties of quercetin, gallium–quercetin nanoparticles (GQNPs) were prepared to integrate iron homeostasis regulation, oxidative stress suppression, and mitochondrial protection for multi‐target ferroptosis inhibition in Parkinson's Disease.
Keyang Xu   +12 more
wiley   +1 more source

Endogenous monoamine oxidase inhibitory activity and HPA activation in the pig [PDF]

open access: yes, 1999
Previously we have shown that an increase in endogenous monoamine oxidase A inhibitory activity (MAO-AI), measured in human saliva, both precedes and predicts psychological stress-induced activation of the hypothalamic pituitary adrenal (HPA) axis, as ...
Evans, P.   +5 more
core   +1 more source

Design and Synthesis of Novel and Potent Monoamine Oxidase Inhibitors

open access: yesCHIMIA, 1995
Reversible and selective monoamine oxidase-A inhibitors (RIMA's) like moclobemide (Aurorix®) have rehabilitated the use of MAO inhibitors as drugs of choice in depression.
Quirico Branca   +4 more
doaj   +2 more sources

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