Novel perspectives in redox biology and pathophysiology of failing myocytes: modulation of the intramyocardial redox milieu for therapeutic interventions - A review article from the Working Group of Cardiac Cell Biology, Italian Society of Cardiology [PDF]
, 2016 The prevalence of heart failure (HF) is still increasing worldwide, with enormous human, social, and economic costs, in spite of huge efforts in understanding pathogeneticmechanisms and in developing effective therapies that have transformed this ...
Angelini, Annalisa +8 more
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Examination of the Monoamine Oxidase A Gene Promoter on Motivation to Exercise and Levels of Voluntary Physical Activity [PDF]
, 2017 Purpose: The purpose of this study was to examine the genetic basis underlying voluntary exercise. Monoamine oxidase A (MAO-A) is an enzyme that acts on monoamine neurotransmitters, such as dopamine, to cause inactivation. There are several polymorphisms
Kinney, Erin M.
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Design and Synthesis of Novel and Potent Monoamine Oxidase Inhibitors
CHIMIA, 1995 Reversible and selective monoamine oxidase-A inhibitors (RIMA's) like moclobemide (Aurorix®) have rehabilitated the use of MAO inhibitors as drugs of choice in depression.
Quirico Branca +4 more
doaj +2 more sources
Expression regulation of MAO isoforms in monocytic cells in response to Th2 cytokines [PDF]
, 2005 Background: Th2-cytokines, such as interleukins-4 and –13 (IL-4, IL-13), have been identified as alternative stimuli of monocytes/macrophages. We have recently profiled the gene-expression pattern of IL-4-teated human peripheral monocytes and found that ...
Billett, E +4 more
core
The inhibition of monoamine oxidase by harmine derivatives
Results in Chemistry, 2022 The monoamine oxidase (MAO) enzymes are established targets for the treatment of neuropsychiatric and neurodegenerative disorders. Inhibitors of MAO-A have been used for many decades in the treatment of depression while MAO-B inhibitors are used in ...
Theo Myburg +2 more
doaj +1 more source
Smoking-induced long-lasting modifications of human platelet serotonin catabolism through a MAO epigenetic regulation [PDF]
, 2008 Postulating that serotonin, secreted from smoking-activated platelets, could be involved in smoking-induced vascular modifications, we studied 115 men distributed in smokers (S), former smokers (FS) and never smokers (NS).
Alain Simon +8 more
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Organic Cation Transporter 3 (OCT3) Is Localized to Intracellular and Surface Membranes in Select Glial and Neuronal Cells Within the Basolateral Amygdaloid Complex of Both Rats and Mice [PDF]
, 2016 Organic cation transporter 3 (OCT3) is a high-capacity, low-affinity transporter that mediates corticosterone-sensitive uptake of monoamines including norepinephrine, epinephrine, dopamine, histamine and serotonin. OCT3 is expressed widely throughout the
Chan, June +3 more
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Bad Nature, Bad Nurture, and Testimony Regarding MAOA and SLC6A4 Genotyping in Murder Trials [PDF]
, 2007 Recent research—in which subjects were studied longitudinally from childhood until adulthood—has started to clarify how a child’s environment and genetic makeup interact to create a violent adolescent or adult.
Farahany, Nita A. +3 more
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Benzo[b]tiophen-3-ol derivatives as effective inhibitors of human monoamine oxidase: design, synthesis, and biological activity [PDF]
, 2019 A series of benzo[b]thiophen-3-ols were synthesised and investigated as potential human monoamine oxidase (hMAO) inhibitors in vitro as well as ex vivo in rat cortex synaptosomes by means of evaluation of 3,4-dihydroxyphenylacetic acid/dopamine (DOPAC/DA)
Alcaro, Stefano +13 more
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MAO-A and the EEG Recognition Memory Signal in Left Parietal Cortex [PDF]
, 2014 A key part of episodic memory, or memory for the events of our lives, is recognition memory. Recognition memory is the ability to remember previously encountered stimuli.
Curran, Tim +3 more
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