Case Report: A possible novel adult-onset, progressive MAO-A hypofunction
Frontiers in NeuroscienceWe describe the clinical presentation, pathophysiology, and successful treatment of a previously undocumented adult onset, progressive form of monoamine oxidase A hypofunction.
Stefan Berteau, Erik Armitano
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Computer-aided approach for the identification of lead molecules as the inhibitors of cholinesterase’s and monoamine oxidases: Novel target for the treatment of Alzheimer disease [PDF]
Journal of the Serbian Chemical SocietyMolecular docking is a promising and reliable technology for the purpose of discovering lead compounds via virtual screening. In addition to allowing for the testing of a large number of compounds, it also allows for the determination of how the selected
Ejaz Syeda Abida +4 more
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Computation-based experimentation: Identification of piperazine containing antidepressants
Pakistan Journal of Pharmaceutical Sciences, 2021 Depression, a common mental disorder, is one of the major contributors to the overall global burden with more than 264 million individuals affected worldwide. Monoamine oxidase inhibitors (MAOIs) have well-known efficacy for treating depression and other
Saman Usmani +6 more
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Monoamine Oxidase and Behaviour
Annals of Medicine, 1995 Item does not contain ...
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Inhibition of monoamine oxidase B by N-methyl-2-phenylmaleimides [PDF]
, 2009 Based on a recent report that 1-methyl-3-phenylpyrrolyl analogues are moderately potent reversible inhibitors of the enzyme monoamine oxidase B (MAO-B), a series of structurally related N-methyl-2-phenylmaleimidyl analogues has been prepared and ...
Petzer, Jacobus P. +4 more
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Crystallization of Human Monoamine Oxidase B [PDF]
, 2023 : The interest in monoamine oxidases A and B (MAO A and B) is due to their central role in regulating the balance of neurotransmitters, both in the central nervous system and in peripheral organs.
Mattevi, Andrea +2 more
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Synthesis of the flavocoenzyme of monoamine oxidase [PDF]
FEBS Letters, 1971 Reaction scheme is entirely in accord with our own conclusion that the go-substituent in the case of MAO-flavin must be a functional group devoid of acid-base properties, though capable of donating electrons to and accepting excitons from the flavin nucleus.
Ghisla, Sandro, Hemmerich, Peter
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Inhibition of monoamine oxidase by E-styrylisatin analogues [PDF]
, 2009 Previous studies have shown that (E)-8-(3-chlorostyryl)caffeine (CSC) is a specific reversible inhibitor of human monoamine oxidase B (MAO-B) and does not bind to human MAO-A.
Petzer, Jacobus P. +4 more
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Frontiers in PharmacologyThe trend of betel quid chewing has witnessed a gradual upsurge in recent years, indicating increased dependence on betel quid/betel-nut and complications of withdrawal. Dedicated efforts towards the development of effective cessation strategies are thus
Sorbomita Chakraborty +3 more
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Interactions of 1-methyl-3-phenylpyrrolidine and 3-methyl-1-phenyl-3-azabicyclo[3.1.0]hexane with monoamine oxidase B [PDF]
, 2010 The parkinsonian inducing agent 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and its corresponding five-membered ring analogue 1-methyl-3-phenyl-3-pyrroline are cyclic tertiary allylamines and good substrates of monoamine oxidase B (MAO-B).
Petzer, Jacobus P. +5 more
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