Results 11 to 20 of about 45,533 (284)

3-Coumaranone derivatives as inhibitors of monoamine oxidase [PDF]

open access: yesDrug Design, Development and Therapy, 2015
Adriaan S Van Dyk,1,2 Jacobus P Petzer,1,2 Anél Petzer,1 Lesetja J Legoabe1 1Centre of Excellence for Pharmaceutical Sciences, 2Pharmaceutical Chemistry, School of Pharmacy, North-West University, Potchefstroom, South Africa Abstract: The ...
Van Dyk AS   +3 more
doaj   +1 more source

The role of the monoamine oxidase A gene in moderating the response to adversity and associated antisocial behavior: a review [PDF]

open access: yesPsychology Research and Behavior Management, 2014
Macià Buades-Rotger,1,2 David Gallardo-Pujol1,3 1Department of Personality, Faculty of Psychology, University of Barcelona, Barcelona, Spain; 2Department of Neurology, University of Lübeck, Lübeck, Germany; 3Institute for Brain ...
Buades-Rotger M, Gallardo-Pujol D
doaj   +1 more source

MONOAMINE-OXIDASE INHIBITORS [PDF]

open access: yesThe Lancet, 1964
Publisher Summary This chapter describes the various classes of chemical compounds, which have an inhibitory action on monoamine oxidase (MAO). The chapter discusses the current theories of the function of monoamine oxidase and the possible mechanism by which the MAO inhibitors (MAOI) react with MAO.
  +7 more sources

Monoamine oxidase inhibitors and neuroprotective mechanisms

open access: yesPsychiatry and Clinical Psychopharmacology, 2021
There has been a resurgence of interest in recent years in monoamine oxidase inhibitors, primarily because of the demonstrated neuroprotective and/ or neurorescue properties of several of these drugs in a variety of toxic situations in vivo and in vitro.
Glen Baker   +4 more
doaj   +1 more source

Platelet monoamine oxidase activity in alcoholics with and without a family history of alcoholism [PDF]

open access: yes, 2000
A number of studies point at platelet monoamine oxidase (MAO) activity being reduced in alcoholics with a family history of drinking, this being a possible vulnerability marker for alcoholism.
Bondy, Brigitta   +5 more
core   +1 more source

STUDY MOLECULES DOCKING OF ALKALOIDS IN KRATOM ON SEROTONIN TRANSPORTER (SERT), NOREPINEPHRINE TRANSPORTER (NET), AND MONOAMINE OXIDASE (MAO)

open access: yesJurnal Kimia Riset, 2023
Kratom (Mitragyna speciosa Korth) is a tropical plant originating from Southeast Asia that predominantly contains alkaloid compounds and can potentially maintain levels of monoamine compounds in the body to treat depression.
Dandi Irawan   +2 more
doaj   +1 more source

N-methyl-N-((1-methyl-5-(3-(1-(2-methylbenzyl)piperidin-4-yl)propoxy)-1H-indol-2-yl)methyl)prop-2-yn-1-amine, a new cholinesterase and monoamine oxidase dual inhibitor [PDF]

open access: yes, 2014
On the basis of N-((5-(3-(1-benzylpiperidin-4-yl)propoxy)-1-methyl-1H-indol-2-yl)methyl)-N-methylprop-2-yn-1-amine (II, ASS234) and QSAR predictions, in this work we have designed, synthesized, and evaluated a number of new indole derivatives from which ...
Bautista-Aguilera, O.M.   +30 more
core   +1 more source

Site-specific expression of amine oxidases in breast cancer metastases

open access: yesTumor Biology, 2018
We aimed to evaluate the expression of amine oxidase-related proteins in metastatic breast cancer tissue and determine its clinical implication. A tissue microarray was constructed from a total of 126 metastatic breast tumors (31 bone metastases (24.6%),
Yoon Jin Cha, Woo Hee Jung, Ja Seung Koo
doaj   +1 more source

Peripheral modulation of antidepressant targets MAO-B and GABAAR by harmol induces mitohormesis and delays aging in preclinical models

open access: yesNature Communications, 2023
Reversible and sub-lethal stresses to the mitochondria elicit a program of compensatory responses that ultimately improve mitochondrial function, a conserved anti-aging mechanism termed mitohormesis.
Luis Filipe Costa-Machado   +27 more
doaj   +1 more source

Development of Novel Fluorine-18 Labeled PET Radioligands for Monoamine Oxidase B (MAO-B) [PDF]

open access: yes, 2013
Monoamine oxidases (MAO-A and MAO-B) are important enzymes regulating the levels of monoaminergic neurotransmitters. Selective and irreversible MAO-B inhibitors such as L-deprenyl and rasagiline are clinically used for the treatment of psychiatric and ...
Nag, Sangram
core   +1 more source

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