Results 11 to 20 of about 36,956 (236)

Monoamine oxidase inhibitors and neuroprotective mechanisms

open access: yesPsychiatry and Clinical Psychopharmacology, 2021
There has been a resurgence of interest in recent years in monoamine oxidase inhibitors, primarily because of the demonstrated neuroprotective and/ or neurorescue properties of several of these drugs in a variety of toxic situations in vivo and in vitro.
Glen Baker   +4 more
doaj   +1 more source

MONOAMINE-OXIDASE INHIBITORS [PDF]

open access: yesThe Lancet, 1964
Publisher Summary This chapter describes the various classes of chemical compounds, which have an inhibitory action on monoamine oxidase (MAO). The chapter discusses the current theories of the function of monoamine oxidase and the possible mechanism by which the MAO inhibitors (MAOI) react with MAO.
  +7 more sources

STUDY MOLECULES DOCKING OF ALKALOIDS IN KRATOM ON SEROTONIN TRANSPORTER (SERT), NOREPINEPHRINE TRANSPORTER (NET), AND MONOAMINE OXIDASE (MAO)

open access: yesJurnal Kimia Riset, 2023
Kratom (Mitragyna speciosa Korth) is a tropical plant originating from Southeast Asia that predominantly contains alkaloid compounds and can potentially maintain levels of monoamine compounds in the body to treat depression.
Dandi Irawan   +2 more
doaj   +1 more source

Peripheral modulation of antidepressant targets MAO-B and GABAAR by harmol induces mitohormesis and delays aging in preclinical models

open access: yesNature Communications, 2023
Reversible and sub-lethal stresses to the mitochondria elicit a program of compensatory responses that ultimately improve mitochondrial function, a conserved anti-aging mechanism termed mitohormesis.
Luis Filipe Costa-Machado   +27 more
doaj   +1 more source

Site-specific expression of amine oxidases in breast cancer metastases

open access: yesTumor Biology, 2018
We aimed to evaluate the expression of amine oxidase-related proteins in metastatic breast cancer tissue and determine its clinical implication. A tissue microarray was constructed from a total of 126 metastatic breast tumors (31 bone metastases (24.6%),
Yoon Jin Cha, Woo Hee Jung, Ja Seung Koo
doaj   +1 more source

Pathological changes in platelet histamine oxidases in atopic eczema

open access: yesMediators of Inflammation, 1993
Increased plasma histamine levels were associated with significantly lowered diamine and type B monoamine oxidase activities in platelet-rich plasma of atopic eczema (AE) patients.
Reinhold Kiehl, Gruia Ionescu
doaj   +1 more source

Coumarin analogue 3-methyl-7H-furo[3,2-g] chromen-7-one as a possible antiparkinsonian agent

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2019
Introduction: Parkinson’s disease is the second most common neurodegenerative disease. Monoamine oxidase B inhibitors are used in the treatment of this disease concomitantly with levodopa or as monotherapy.
María del Pilar Olaya   +4 more
doaj   +1 more source

Monoamine Oxidase and Cholinesterase Inhibition Profiles of Semicarbazone and Thiosemicarbazone Derivatives. [PDF]

open access: yesChem Biodivers
Thiosemicarbazones generally show higher MAO‐B inhibitory potential than their corresponding semicarbazones, and particularly T6 is the most potent, which contains R = H and X = S in its Tail Unit, with an IC50 value of 6.45 µM with SI of 3.6. ABSTRACT Twenty semicarbazone and thiosemicarbazone derivatives (T1–T20) were synthesized and evaluated for ...
Bindra S   +11 more
europepmc   +2 more sources

Recent progress in directed evolution of stereoselective monoamine oxidases

open access: yesBioresources and Bioprocessing, 2019
Monoamine oxidases (MAOs) use molecular dioxygen as oxidant to catalyze the oxidation of amines to imines. This type of enzyme can be employed for the synthesis of primary, secondary, and tertiary amines by an appropriate deracemization protocol ...
Jiaqi Duan   +5 more
doaj   +1 more source

Hospitalized Patients' Perceived Knowledge and Risk of Monoamine Oxidase Inhibitor Medications Before and After a Pharmacist's Classroom-Based Education

open access: yesINNOVATIONS in Pharmacy, 2010
Objective: Assess if a classroom-based pharmacy education service for hospitalized headache patients newly prescribed a monoamine oxidase inhibitor (MAOI) results in, 1) higher self-perceived medication knowledge, or 2) lower perceived risk of using ...
Richard G. Wenzel, Jon C. Schommer
doaj   +1 more source

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