Coumarin analogue 3-methyl-7H-furo[3,2-g] chromen-7-one as a possible antiparkinsonian agent
Biomédica: revista del Instituto Nacional de Salud, 2019 Introduction: Parkinson’s disease is the second most common neurodegenerative disease. Monoamine oxidase B inhibitors are used in the treatment of this disease concomitantly with levodopa or as monotherapy.
María del Pilar Olaya +4 more
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Recent progress in directed evolution of stereoselective monoamine oxidases
Bioresources and Bioprocessing, 2019 Monoamine oxidases (MAOs) use molecular dioxygen as oxidant to catalyze the oxidation of amines to imines. This type of enzyme can be employed for the synthesis of primary, secondary, and tertiary amines by an appropriate deracemization protocol ...
Jiaqi Duan +5 more
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INNOVATIONS in Pharmacy, 2010 Objective: Assess if a classroom-based pharmacy education service for hospitalized headache patients newly prescribed a monoamine oxidase inhibitor (MAOI) results in, 1) higher self-perceived medication knowledge, or 2) lower perceived risk of using ...
Richard G. Wenzel, Jon C. Schommer
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Case Report: A possible novel adult-onset, progressive MAO-A hypofunction
Frontiers in NeuroscienceWe describe the clinical presentation, pathophysiology, and successful treatment of a previously undocumented adult onset, progressive form of monoamine oxidase A hypofunction.
Stefan Berteau, Erik Armitano
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Computer-aided approach for the identification of lead molecules as the inhibitors of cholinesterase’s and monoamine oxidases: Novel target for the treatment of Alzheimer disease [PDF]
Journal of the Serbian Chemical SocietyMolecular docking is a promising and reliable technology for the purpose of discovering lead compounds via virtual screening. In addition to allowing for the testing of a large number of compounds, it also allows for the determination of how the selected
Ejaz Syeda Abida +4 more
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Computation-based experimentation: Identification of piperazine containing antidepressants
Pakistan Journal of Pharmaceutical Sciences, 2021 Depression, a common mental disorder, is one of the major contributors to the overall global burden with more than 264 million individuals affected worldwide. Monoamine oxidase inhibitors (MAOIs) have well-known efficacy for treating depression and other
Saman Usmani +6 more
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Monoamine Oxidase and Behaviour
Annals of Medicine, 1995 Item does not contain ...
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Development of Novel Fluorine-18 Labeled PET Radioligands for Monoamine Oxidase B (MAO-B) [PDF]
, 2013 Monoamine oxidases (MAO-A and MAO-B) are important enzymes regulating the levels of monoaminergic neurotransmitters. Selective and irreversible MAO-B inhibitors such as L-deprenyl and rasagiline are clinically used for the treatment of psychiatric and ...
Nag, Sangram
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MONOAMINE OXIDASE A (MAOA), CHILDHOOD TRAUMA, ALCOHOLISM AND AGGRESSION [PDF]
, 2008 Women who have experienced childhood sexual abuse (CSA) have an increased risk of alcoholism and antisocial personality disorder (ASPD). Among males, a functional polymorphism (MAOA-LPR, monoamine oxidase A linked polymorphic region) in the promoter ...
DUCCI, FRANCESCA
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Synthesis of the flavocoenzyme of monoamine oxidase [PDF]
FEBS Letters, 1971 Reaction scheme is entirely in accord with our own conclusion that the go-substituent in the case of MAO-flavin must be a functional group devoid of acid-base properties, though capable of donating electrons to and accepting excitons from the flavin nucleus.
Ghisla, Sandro, Hemmerich, Peter
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